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View Structure Prediction Details

Protein: dcap-2
Organism: Caenorhabditis elegans
Length: 786 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dcap-2.

Description E-value Query
Range
Subject
Range
CE39373 - WBGene00003582 locus:dcap-2 status:Partially_confirmed SW:O62255 protein_id:CAJ43918.1
464.0 [0..19] [786..42]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEISTENWCK KPKNRSIFSK NISFQKQNKS TEEPPSSVQK LLASLQQAQN KSDLSEQPST  60
   61 SKPKKNEKRK KAVAQAPASA PAPGPEEKKK QPKRASVGAR MQQQAENARI SQTKRPRQVS 120
  121 TSKGSSRNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [130-395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAPEQQNYQQ QQQQYKGPRI PTDILDELEF RFISNMVECE INDNIRVCFH LELAHWYYID  60
   61 HMVEDDKISG CPNVGSRDFN FQMCQHCRVL RKYAHRADEV LAKFREYKST VPTYGAILVD 120
  121 PEMDHVVLVQ SYFAKGKNWG FPKGKINQAE PPRDAAIRET FEETGFDFGI YSEKEKKFQR 180
  181 FINDGMVRLY LVKNVPKDFN FQPQTRKEIR KIEWFKIDDL PTDKTDELPA YLQGNKFYMV 240
  241 MPFVKDIQIY VQKEKEKLRR RKAEAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.0
Match: 2a6tA
Description: Crystal structure of S.pombe mRNA decapping enzyme Dcp2p
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [396-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSTPSSSIFS QLFPAQPPPP VPEDATPTRP MYKRLTSEEL FSAFKNPPAG EVARPTLPDM  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.39794
Match: 1i3qA
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [456-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPAVNGLDTL AVLGICTPLK PGASLNEFSG APQNCPMISE EAGSPADPSA EIGFAMPMDL  60
   61 KQPVVTSDHP WQHHKISDSS APPQTLESHQ GWLDTQLVNT IMHSPNHPLP PTSNSPATPT 120
  121 AVLGHLIGKP IQPQAILPQA ATPTALGSAE KPKSSRISLS DNSAFKAISS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [626-786]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQKQSIPKAT AAPPSTEKTR SASLSGSSQV VGKPARNLFN SVVSPVSSGI QSIQGDGGAW  60
   61 EDVWFREQLA ATTTAGTSIS SLAASNQELA MINREETPIE DPYFKQQAYQ KAQKAQSLIP 120
  121 ACSQWTNSIK LDIDYVVGPL SFWMQQFSTK SPVSGTGPQL P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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