YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RFC1
Organism: Homo sapiens
Length: 1148 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFC1.

Description E-value Query
Range
Subject
Range
gi|109074009 - gi|109074009|ref|XP_001091287.1| PREDICTED: replication factor C large subunit isoform 3 [Macaca mul...
0.0 [1..1139] [1..1139]
gi|30353858 - gi|30353858|gb|AAH51786.1| RFC1 protein [Homo sapiens]
gi|167774195 - gi|167774195|gb|ABZ92532.1| replication factor C (activator 1) 1, 145kDa [synthetic construct]
0.0 [1..1139] [1..1139]
gi|114593608 - gi|114593608|ref|XP_001140765.1| PREDICTED: replication factor C large subunit isoform 4 [Pan troglo...
0.0 [1..1139] [1..1139]
gi|109499686, gi... - gi|109500605|ref|XP_001078203.1| PREDICTED: similar to Activator 1 140 kDa subunit (Replication fact...
0.0 [1..1126] [1..1108]
gi|73951876 - gi|73951876|ref|XP_536259.2| PREDICTED: similar to replication factor C large subunit [Canis familia...
0.0 [1..1120] [1..1117]

Back

Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIRKFFGVI PSGKKLVSET VKKNEKTKSD EETLKAKKGI KEIKVNSSRK EDDFKQKQPS  60
   61 KKKRIIYDSD SESEETLQVK NAKKPPEKLP VSSKPGKISR QDPVTYISET DEEDDFMCKK 120
  121 AASKSKENGR STNSHLGTSN MKKNEENTKT KNKPL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [156-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPIKLTPTSV LDYFGTGSVQ RSNKKMVASK RKELSQNTDE SGLNDEAIAK QLQLDEDAEL  60
   61 ERQLHEDEEF ARTLAMLDEE PKTKKARKDT EAGETFSSVQ ANLSKAEKHK YPHKVKTAQV 120
  121 SDERKSYSPR KQSKYESSKE SQQHSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [302-898]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSADKIGEVS SPKASSKLAI MKRKEESSYK EIEPVASKRK ENAIKLKGET KTPKKTKSSP  60
   61 AKKESVSPED SEKKRTNYQA YRSYLNREGP KALGSKEIPK GAENCLEGLI FVITGVLESI 120
  121 ERDEAKSLIE RYGGKVTGNV SKKTNYLVMG RDSGQSKSDK AAALGTKIID EDGLLNLIRT 180
  181 MPGKKSKYEI AVETEMKKES KLERTPQKNV QGKRKISPSK KESESKKSRP TSKRDSLAKT 240
  241 IKKETDVFWK SLDFKEQVAE ETSGDSKARN LADDSSENKV ENLLWVDKYK PTSLKTIIGQ 300
  301 QGDQSCANKL LRWLRNWQKS SSEDKKHAAK FGKFSGKDDG SSFKAALLSG PPGVGKTTTA 360
  361 SLVCQELGYS YVELNASDTR SKSSLKAIVA ESLNNTSIKG FYSNGAASSV STKHALIMDE 420
  421 VDGMAGNEDR GGIQELIGLI KHTKIPIICM CNDRNHPKIR SLVHYCFDLR FQRPRVEQIK 480
  481 GAMMSIAFKE GLKIPPPAMN EIILGANQDI RQVLHNLSMW CARSKALTYD QAKADSHRAK 540
  541 KDIKMGPFDV ARKVFAAGEE TAHMSLVDKS DLFFHDYSIA PLFVQENYIH VKPVAAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.30103
Match: 1oz4A
Description: VCP/p97
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [899-927]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDMKKHLMLL SRAADSICDG DLVDSQIRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.39794
Match: 1iqpA
Description: Replication factor C
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [928-1148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQNWSLLPAQ AIYASVLPGE LMRGYMTQFP TFPSWLGKHS STGKHDRIVQ DLALHMSLRT  60
   61 YSSKRTVNMD YLSLLRDALV QPLTSQGVDG VQDVVALMDT YYLMKEDFEN IMEISSWGGK 120
  121 PSPFSKLDPK VKAAFTRAYN KEAHLTPYSL QAIKASRHST SPSLDSEYNE ELNEDDSQSD 180
  181 EKDQDAIETD AMIKKKTKSS KPSKPEKDKE PRKGKGKSSK K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.0
Match: 1sxjA
Description: Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle