YRC Public Data Repository - Protein Structure Prediction

Protein:	CFA_ECOLI
Organism:	Escherichia coli
Length:	382 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CFA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|16764775, gi\|... - gi\|16764775\|ref\|NP_460390.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella typhimurium L... gi\|29141754, gi\|... - gi\|29141754\|ref\|NP_805096.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica subs... gi\|16502782, gi\|... - pir\|\|AC0696 cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) [imported] - Salmonella ente... gi\|19880627 - gi\|19880627\|gb\|AAM00427.1\|AF417203_1 cyclopropane fatty acid synthase [Salmonella enterica subsp. en... gi\|16760486 - gi\|16760486\|ref\|NP_456103.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica subs... gi\|205347612, gi... - gi\|205347612\|gb\|EDZ34243.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica subsp... gi\|205339483, gi... - gi\|205339483\|gb\|EDZ26247.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica subsp... gi\|197290941, gi... - gi\|197290941\|gb\|EDY30294.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica subsp... gi\|205323644, gi... - gi\|205323644\|gb\|EDZ11483.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica subsp... gi\|194736258, gi... - gi\|194736258\|ref\|YP_002114438.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica ... gi\|194457151, gi... - gi\|194470787\|ref\|ZP_03076771.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica s... gi\|194407050, gi... - gi\|194448746\|ref\|YP_002045428.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica ... gi\|195634453, gi... - gi\|195634453\|gb\|EDX52805.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica subsp... gi\|238913172 - gi\|238913172\|ref\|ZP_04657009.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica s... gi\|224584064, gi... - gi\|224584064\|ref\|YP_002637862.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica ... gi\|214001978 - gi\|214001978\|ref\|ZP_03412713.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica s... gi\|213646435 - gi\|213646435\|ref\|ZP_03376488.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica s... gi\|213585077 - gi\|213585077\|ref\|ZP_03366903.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica s... gi\|200390331, gi... - gi\|200390331\|ref\|ZP_03216942.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica s... gi\|198244094, gi... - gi\|198244094\|ref\|YP_002215707.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica ... gi\|197241160, gi... - gi\|197262905\|ref\|ZP_03162979.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica s... gi\|197215466, gi... - gi\|197251763\|ref\|YP_002146618.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica ... gi\|213426010 - gi\|213426010\|ref\|ZP_03358760.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica s... gi\|207857069, gi... - gi\|207857069\|ref\|YP_002243720.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica ... gi\|205272640, gi... - gi\|205352859\|ref\|YP_002226660.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica ... gi\|204322969, gi... - gi\|204927627\|ref\|ZP_03218828.1\| cyclopropane-fatty-acyl-phospholipid synthase [Salmonella enterica s... lcl\|NC_016856.1_... - [gene=cfa] [protein=cyclopropane-fatty-acyl-phospholipid synthase] [protein_id=YP_005237296.1] [loca... gi\|62180016, gi\|... - gi\|62180016\|ref\|YP_216433.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica subs...	362.0	[0..1]	[382..1]
gi\|56413604, gi\|... - gi\|56413604\|ref\|YP_150679.1\| cyclopropane fatty acyl phospholipid synthase [Salmonella enterica subs...	362.0	[0..1]	[382..1]
gi\|24113051, gi\|... - gi\|24113051\|ref\|NP_707561.1\| cyclopropane fatty acyl phospholipid synthase [Shigella flexneri 2a str... gi\|30063177, gi\|... - gi\|30063177\|ref\|NP_837348.1\| cyclopropane fatty acyl phospholipid synthase [Shigella flexneri 2a str... gi\|110805639, gi... - gi\|110805639\|ref\|YP_689159.1\| cyclopropane fatty acyl phospholipid synthase [Shigella flexneri 5 str...	356.0	[0..1]	[382..1]
gi\|194425906, gi... - gi\|75212997\|ref\|ZP_00712995.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera... gi\|209918976, gi... - gi\|209918976\|ref\|YP_002293060.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli SE1... gi\|157155437, gi... - gi\|75190700\|ref\|ZP_00703967.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera... gi\|218554229, gi... - gi\|218554229\|ref\|YP_002387142.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli IAI... gi\|218351956, gi... - gi\|218695224\|ref\|YP_002402891.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli 559... gi\|193064956, gi... - gi\|75257080\|ref\|ZP_00728640.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera... gi\|75230891, gi\|... - gi\|75230891\|ref\|ZP_00717340.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera... gi\|193071596, gi... - gi\|75214855\|ref\|ZP_00713338.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera...	356.0	[0..1]	[382..1]
gi\|81241285, gi\|... - gi\|82777137\|ref\|YP_403486.1\| cyclopropane fatty acyl phospholipid synthase [Shigella dysenteriae Sd1...	356.0	[0..1]	[382..1]
gi\|209769350, gi... - pir\|\|F85773 cyclopropane fatty acyl phospholipid synthase [imported] - Escherichia coli (strain O157... gi\|15802075, gi\|... - gi\|15802075\|ref\|NP_288097.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli O157:H7... gi\|15831624, gi\|... - gi\|15831624\|ref\|NP_310397.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli O157:H7... gi\|15831624, gi\|... - gi\|15831624\|ref\|NP_310397.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli O157:H7... gi\|208816625, gi... - gi\|208816625\|ref\|ZP_03257745.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157... gi\|208740600, gi... - gi\|208820477\|ref\|ZP_03260797.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157... gi\|209395995, gi... - gi\|209395995\|ref\|YP_002270731.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O15... gi\|217318007, gi... - gi\|217328660\|ref\|ZP_03444741.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157... gi\|168771674, gi... - gi\|189359635\|gb\|EDU78054.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157:H7 ... gi\|188998793, gi... - gi\|188998793\|gb\|EDU67779.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157:H7 ... gi\|195940241 - gi\|195940241\|ref\|ZP_03085623.1\| cyclopropane fatty acyl phospholipid synthase [Escherichia coli O157... gi\|208810458, gi... - gi\|208810458\|ref\|ZP_03252334.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157... gi\|168752348, gi... - gi\|188013785\|gb\|EDU51907.1\| cyclopropane-fatty-acyl-phospholipid synthase [Escherichia coli O157:H7 ... gi\|254592680, gi... - gi\|254793280\|ref\|YP_003078117.1\| cyclopropane fatty acyl phospholipid synthase (unsaturated-phosphol...	356.0	[0..1]	[382..1]
gi\|187427943, gi... - gi\|75175188\|ref\|ZP_00695506.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera... gi\|82543969, gi\|... - gi\|82543969\|ref\|YP_407916.1\| cyclopropane fatty acyl phospholipid synthase [Shigella boydii Sb227], ...	353.0	[0..1]	[382..1]
gi\|77959196 - gi\|77959196\|ref\|ZP_00823218.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera...	344.0	[0..1]	[382..1]
gi\|238787135, gi... - gi\|77975296\|ref\|ZP_00830832.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera...	342.0	[0..1]	[382..1]
gi\|238796361, gi... - gi\|77961725\|ref\|ZP_00825557.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera...	342.0	[0..1]	[382..1]

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Predicted Domain #1

Region A:
Residues: [1-120]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSCIEEVS VPDDNWYRIA NELLSRAGIA INGSAPADIR VKNPDFFKRV LQEGSLGLGE  60
   61 SYMDGWWECD RLDMFFSKVL RAGLENQLPH HFKDTLRIAG ARLFNLQSKK RAWIVGKEHY 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [121-382]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLGNDLFSRM LDPFMQYSCA YWKDADNLES AQQAKLKMIC EKLQLKPGMR VLDIGCGWGG  60
   61 LAHYMASNYD VSVVGVTISA EQQKMAQERC EGLDVTILLQ DYRDLNDQFD RIVSVGMFEH 120
  121 VGPKNYDTYF AVVDRNLKPE GIFLLHTIGS KKTDLNVDPW INKYIFPNGC LPSVRQIAQS 180
  181 SEPHFVMEDW HNFGADYDTT LMAWYERFLA AWPEIADNYS ERFKRMFTYY LNACAGAFRA 240
  241 RDIQLWQVVF SRGVENGLRV AR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	1kp9A
Description:	CmaA1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.62377578202456	bayes_pls_golite062009
transferase activity	1.20063885869845	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.14636302691827	bayes_pls_golite062009
methyltransferase activity	1.12602040164126	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.535429947810431	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: