YRC Public Data Repository - Protein Structure Prediction

Protein:	PDXJ_ECOLI
Organism:	Escherichia coli
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDXJ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75513174 - gi\|75513174\|ref\|ZP_00735616.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli 5... gi\|75257988 - gi\|75257988\|ref\|ZP_00729462.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli E... gi\|75237690 - gi\|75237690\|ref\|ZP_00721706.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli E... gi\|75228861 - gi\|75228861\|ref\|ZP_00715462.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli B... gi\|75209488 - gi\|75209488\|ref\|ZP_00709713.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli B... gi\|83586784 - gi\|83586784\|ref\|ZP_00925415.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli 1...	411.0	[0..1]	[243..6]
PDXJ_SHIBS - Pyridoxine 5'-phosphate synthase OS=Shigella boydii serotype 4 (strain Sb227) GN=pdxJ PE=3 SV=1 gi\|187430769, gi... - gi\|187733777\|ref\|YP_001881343.1\| pyridoxine 5'-phosphate synthase [Shigella boydii CDC 3083-94], gi\|...	411.0	[0..1]	[243..1]
gi\|75178159 - gi\|75178159\|ref\|ZP_00698218.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Shigella boydii BS...	411.0	[0..1]	[243..6]
gi\|110642726, gi... - gi\|110642726\|ref\|YP_670456.1\| pyridoxine 5'-phosphate synthase [Escherichia coli 536], gi\|110344318\|... gi\|190905698, gi... - gi\|191174007\|ref\|ZP_03035524.1\| pyridoxine 5'-phosphate synthase [Escherichia coli F11], gi\|19090569... gi\|218559485, gi... - gi\|218559485\|ref\|YP_002392398.1\| pyridoxine 5'-phosphate synthase [Escherichia coli S88], gi\|2183662... gi\|218428244, gi... - gi\|218690680\|ref\|YP_002398892.1\| pyridoxine 5'-phosphate synthase [Escherichia coli ED1a], gi\|218428...	410.0	[0..1]	[243..1]
gi\|226901440, gi... - gi\|237705074\|ref\|ZP_04535555.1\| pyridoxal phosphate biosynthetic protein PdxJ [Escherichia sp. 3_2_5... gi\|115513909, gi... - gi\|117624785\|ref\|YP_853698.1\| pyridoxal phosphate biosynthetic protein PdxJ [Escherichia coli APEC O... gi\|75237417 - gi\|75237417\|ref\|ZP_00721452.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Escherichia coli F... gi\|91211890, gi\|... - gi\|91211890\|ref\|YP_541876.1\| pyridoxal phosphate biosynthetic protein PdxJ [Escherichia coli UTI89],...	410.0	[0..1]	[243..6]
PDXJ_ECOL6 - Pyridoxine 5'-phosphate synthase OS=Escherichia coli O6 GN=pdxJ PE=3 SV=3 PDXJ_ECOL6 - Pyridoxine 5'-phosphate synthase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=p...	410.0	[0..1]	[243..1]
gi\|227835950, gi... - gi\|227887600\|ref\|ZP_04005405.1\| pyridoxal phosphate biosynthetic protein PdxJ [Escherichia coli 8397... gi\|26248929, gi\|... - gi\|26248929\|ref\|NP_754969.1\| pyridoxal phosphate biosynthetic protein PdxJ [Escherichia coli CFT073]...	410.0	[0..1]	[243..6]
gi\|56383692, gi\|... - gi\|56480141\|ref\|NP_708416.2\| pyridoxal phosphate biosynthetic protein PdxJ [Shigella flexneri 2a str... gi\|110806509, gi... - gi\|110806509\|ref\|YP_690029.1\| pyridoxal phosphate biosynthetic protein PdxJ [Shigella flexneri 5 str... gi\|194419587, gi... - gi\|194432058\|ref\|ZP_03064347.1\| pyridoxine 5'-phosphate synthase [Shigella dysenteriae 1012], gi\|194... gi\|30042222, gi\|... - gi\|30063966\|ref\|NP_838137.1\| pyridoxal phosphate biosynthetic protein PdxJ [Shigella flexneri 2a str...	410.0	[0..1]	[243..1]
gi\|83570800 - gi\|83570800\|ref\|ZP_00922243.1\| COG0854: Pyridoxal phosphate biosynthesis protein [Shigella dysenteri... gi\|24053007, gi\|... - ref\|NP_708416.1\| pyridoxine biosynthesis [Shigella flexneri 2a str. 301], gb\|AAN44123.1\| pyridoxine...	410.0	[0..1]	[243..6]
gi\|15803090, gi\|... - gi\|15803090\|ref\|NP_289121.1\| pyridoxal phosphate biosynthetic protein PdxJ [Escherichia coli O157:H7... gi\|25345853 - gi\|25345853\|pir\|\|C85902 pyridoxine biosynthesis [imported] - Escherichia coli (strain O157:H7, subs...	410.0	[0..1]	[243..1]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELLLGVNI DHIATLRNAR GTAYPDPVQA AFIAEQAGAD GITVHLREDR RHITDRDVRI  60
   61 LRQTLDTRMN LEMAVTEEML AIAVETKPHF CCLVPEKRQE VTTEGGLDVA GQRDKMRDAC 120
  121 KRLADAGIQV SLFIDADEEQ IKAAAEVGAP FIEIHTGCYA DAKTDAEQAQ ELARIAKAAT 180
  181 FAASLGLKVN AGHGLTYHNV KAIAAIPEMH ELNIGHAIIG RAVMTGLKDA VAEMKRLMLE 240
  241 ARG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	116.0
Match:	1m5wA
Description:	Pyridoxine 5'-phosphate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.52383794192252	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: