YRC Public Data Repository - Protein Structure Prediction

Protein:	MURG_ECOLI
Organism:	Escherichia coli
Length:	355 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MURG_ECOLI.

Description	E-value	Query Range	Subject Range
MURG_HAES1 - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam...	273.0	[0..2]	[354..1]
gi\|85833686, gi\|... - gi\|86148540\|ref\|ZP_01066827.1\| N-acetylglucosaminyl transferase [Vibrio sp. MED222], gi\|85833686\|gb\|...	272.0	[0..2]	[354..1]
gi\|84374933, gi\|... - gi\|84394434\|ref\|ZP_00993150.1\| N-acetylglucosaminyl transferase [Vibrio splendidus 12B01], gi\|843749...	269.0	[0..2]	[354..1]
MURG_VIBF1 - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam...	263.0	[0..1]	[354..1]
MURG_MANSM - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam...	259.0	[0..2]	[351..1]
gi\|90438530, gi\|... - gi\|90580228\|ref\|ZP_01236035.1\| N-acetylglucosaminyl transferase [Vibrio angustum S14], gi\|90438530\|g...	258.0	[0..2]	[354..1]
gi\|46156647 - gi\|46156647\|ref\|ZP_00132287.2\| COG0707: UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase ...	257.0	[0..11]	[354..1]
gi\|89074170, gi\|... - gi\|89074170\|ref\|ZP_01160669.1\| N-acetylglucosaminyl transferase [Photobacterium sp. SKA34], gi\|89050...	256.0	[0..2]	[354..1]
gi\|91187948, gi\|... - gi\|91228514\|ref\|ZP_01262436.1\| N-acetylglucosaminyl transferase [Vibrio alginolyticus 12G01], gi\|911...	256.0	[0..2]	[352..1]
MURG_VIBPA - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam... MURG_VIBPA - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosam... gi\|153839053, gi... - gi\|153839053\|ref\|ZP_01991720.1\| undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyl...	255.0	[0..2]	[352..1]

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Predicted Domain #1

Region A:
Residues: [1-355]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGQGKRLMV MAGGTGGHVF PGLAVAHHLM AQGWQVRWLG TADRMEADLV PKHGIEIDFI  60
   61 RISGLRGKGI KALIAAPLRI FNAWRQARAI MKAYKPDVVL GMGGYVSGPG GLAAWSLGIP 120
  121 VVLHEQNGIA GLTNKWLAKI ATKVMQAFPG AFPNAEVVGN PVRTDVLALP LPQQRLAGRE 180
  181 GPVRVLVVGG SQGARILNQT MPQVAAKLGD SVTIWHQSGK GSQQSVEQAY AEAGQPQHKV 240
  241 TEFIDDMAAA YAWADVVVCR SGALTVSEIA AAGLPALFVP FQHKDRQQYW NALPLEKAGA 300
  301 AKIIEQPQLS VDAVANTLAG WSRETLLTMA ERARAASIPD ATERVANEVS RVARA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.0
Match:	1f0kA
Description:	Peptidoglycan biosynthesys glycosyltransferase MurG
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring hexosyl groups	3.04530122157712	bayes_pls_golite062009
catalytic activity	3.02192459767177	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.94500176353224	bayes_pls_golite062009
glucosyltransferase activity	1.8062586862583	bayes_pls_golite062009
transferase activity	1.67770954408305	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.4199532885636	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.30934991061674	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	0.76826617788618	bayes_pls_golite062009
lipopolysaccharide heptosyltransferase activity	0.496539957375041	bayes_pls_golite062009
phosphorylase activity	0.431662083250969	bayes_pls_golite062009
glycogen phosphorylase activity	0.36071680392511	bayes_pls_golite062009
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	0.352122592644471	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.27693350081385	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.22009679964126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: