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View Structure Prediction Details

Protein: nhr-2
Organism: Caenorhabditis elegans
Length: 472 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-2.

Description E-value Query
Range
Subject
Range
gi|13274546 - gi|13274546|gb|AAK17972.1|AF332201_1 nuclear receptor NHR-2 [Caenorhabditis elegans]
236.0 [0..1] [472..3]

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Predicted Domain #1
Region A:
Residues: [1-71]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPMNPELMH YPNQPHMMPG YPMINAYQQS YLQNPAQWTP EMLLCMQMQM QQMVPGTATN  60
   61 STYMPPQSKN T

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [72-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTPNATSPLS QISDRDSGND TISPPLTSQN SATTPNYHNQ PQMQLTPLQQ AKPEKEEISP  60
   61 YAINNILSST QSSPDNGNEA DDKENSSVRR NTFPASSAST KKPRGTPYDR TNTPMTVVPQ 120
  121 MPQFAPDFSN YNLTMNAWSE FF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.996
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [214-313]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKDRCMVCGD NSTGYHYGVQ SCEGCKGFFR RSVHKNIAYV CTKGENCTFS YENCAANRGV  60
   61 RTRCQACRFA KCLAVGMNRD NVRVNKETDK DVKPSVASPN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1ynwB
Description: Crystal Structure of Vitmain D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [314-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEMTSQVKEL TAAFVANMPC STHLTSGTHA IGAIKKFIES VPALSSLLPK DEKALEMSIQ  60
   61 KVMSGILAIR AAFTFDPITF YSCENPVNLL RGGIRNTVFN DCEVALLSGI HILQIVNGGV 120
  121 AEIFTSYCQG LRHQLSQTHL QEIGLCDRLL MRLGPYLNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1e3kA
Description: Progesterone receptor
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle