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View Structure Prediction Details

Protein: gi|7442254
Organism: Plasmodium falciparum
Length: 654 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7442254.

Description E-value Query
Range
Subject
Range
gi|84232, gi|9909 - gi|9909|emb|CAA68268.1| KAHRP [Plasmodium falciparum], pir||A29454 knob-associated histidine-rich pr...
KNOB_PLAFN - Knob-associated histidine-rich protein OS=Plasmodium falciparum (isolate NF7 / Ghana) GN=SD17 PE=3 S...
221.0 [0..1] [654..1]
gi|9864143 - gi|9864143|gb|AAG01323.1|AF275687_1 knob-associated histidine-rich protein [Plasmodium falciparum]
211.0 [0..1] [654..1]
KNOB_PLAFG - Knob-associated histidine-rich protein OS=Plasmodium falciparum (isolate FCR-3 / Gambia) PE=2 SV=1
gi|160358, gi|84224 - gi|84224|pir||A28412 histidine-rich protein precursor - malaria parasite (Plasmodium falciparum), g...
208.0 [0..1] [654..1]
gi|70878103 - gi|70878103|gb|EAN91386.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71648919 - gi|71648919|ref|XP_813237.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
208.0 [0..47] [649..699]
gi|24020878, gi|... - gi|50979202|ref|NP_001003352.1| neurofilament, heavy polypeptide 200kDa [Canis lupus familiaris], gi...
207.0 [0..45] [646..436]
gi|601930, gi|284667 - gi|601930|gb|AAA57152.1| neurofilament-H, pir||A43427 neurofilament triplet H1 protein - rabbit (fra...
200.0 [0..71] [648..40]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSFKNKNTL RRKKAFPVFT KILLVSFLVW VLKCSNNCNN GNGSGDSFDF RNKRTLAQKQ  60
   61 HEHHHHHHHQ HQHQHQAPHQ AHHHHHH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEVNHQAPQV HQQVHGQDQA HHHHHHHHHQ LQPQQPQGTV ANPPSNEPVV KTQVFREARP  60
   61 GGGFKAYEEK YESKHYKLKE NVVDGKKDCD EKYEAANYAF SEECPYTVND YSQENGPNIF 120
  121 ALRKRFPLGM NDEDEEGKEA LAIKDKLPGG LDEYQNQLYG ICNETCTTCG PAAIDYVPAD 180
  181 APNGYAYGGS AH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.460 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.457 a.1.1 Globin-like
View Download 0.364 a.118.8 TPR-like
View Download 0.330 d.153.1 N-terminal nucleophile aminohydrolases (Ntn hydrolases)
View Download 0.322 c.56.3 Peptidyl-tRNA hydrolase

Predicted Domain #3
Region A:
Residues: [280-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSHGNLRGH DNKGSEGYGY EAPYNPGFNG APGSNGMQNY VPPHGAGYSA PYGVPHGAAH  60
   61 GSRYSSFSSV NKYGKHGDEK HHSSKKHEGN DGEGEKKKKS KKHKDHDGEK KKSKKHKDNE 120
  121 DAESVKSKKH KSHDCEKKKS KKHKD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [425-654]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEDAESVKSK KSVKEKGEKH NGKKPCSKKT NEENKNKEKT NNSKSDGSKA HEKKENETKN  60
   61 TAGENKKVDS TSADNKSTNA ATPGAKDKTQ GGKTDKTGAS TNAATNKGQC AAEGATKGAT 120
  121 KEASTSKEAT KEASTSKEAT KEASTSKEAT KEASTSKGAT KEASTTEGAT KGASTTAGST 180
  181 TGATTGANAV QSKDETADKN AANNGEQVMS RGQAQLQEAG KKKKKRGCCG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1w9rA
Description: Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle