YRC Public Data Repository - Protein Structure Prediction

Protein:	FOLX_ECOLI
Organism:	Escherichia coli
Length:	120 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOLX_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|58583747, gi\|... - gi\|58583747\|ref\|YP_202763.1\| dihydroneopterin aldolase [Xanthomonas oryzae pv. oryzae KACC10331], gi...	147.0	[0..1]	[120..20]
gi\|66770185, gi\|... - gi\|66770185\|ref\|YP_244947.1\| dihydroneopterin aldolase [Xanthomonas campestris pv. campestris str. 8... gi\|21233243, gi\|... - gi\|21233243\|ref\|NP_639160.1\| dihydroneopterin aldolase [Xanthomonas campestris pv. campestris str. A...	145.0	[0..5]	[120..1]
gi\|68347245, gi\|... - gi\|70732946\|ref\|YP_262717.1\| dihydroneopterin aldolase [Pseudomonas fluorescens Pf-5], gi\|68347245\|g...	145.0	[0..5]	[118..1]
gi\|94499958, gi\|... - gi\|94499958\|ref\|ZP_01306493.1\| Dihydroneopterin aldolase family protein [Oceanobacter sp. RED65], gi...	144.0	[0..5]	[118..1]
gi\|90311658, gi\|... - gi\|90407235\|ref\|ZP_01215422.1\| dihydroneopterin aldolase [Psychromonas sp. CNPT3], gi\|90311658\|gb\|EA...	144.0	[0..5]	[118..1]
gi\|153819106, gi... - gi\|153819106\|ref\|ZP_01971773.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae NCTC 8457]... gi\|125617384 - gi\|125617384\|gb\|EAZ45952.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae MO10] gi\|227008595, gi... - gi\|227080707\|ref\|YP_002809258.1\| putative dihydroneopterin aldolase FolB [Vibrio cholerae M66-2], gi... gi\|9654950, gi\|1... - gi\|9654950\|gb\|AAF93692.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae O1 biovar El Tor... gi\|126518706, gi... - gi\|153823781\|ref\|ZP_01976448.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae B33], gi\|1... gi\|11270209 - pir\|\|C82313 probable dihydroneopterin aldolase FolB VC0524 [imported] - Vibrio cholerae (strain N169... gi\|121590692, gi... - gi\|121590692\|ref\|ZP_01678025.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae 2740-80], ... gi\|153223810, gi... - gi\|153223810\|ref\|ZP_01954065.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae MAK 757], ... gi\|149739230, gi... - gi\|153826927\|ref\|ZP_01979594.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae MZO-2], gi... gi\|121629158, gi... - gi\|121728546\|ref\|ZP_01681568.1\| dihydroneopterin aldolase FolB, putative [Vibrio cholerae V52], gi\|1... gi\|227012350, gi... - gi\|227116900\|ref\|YP_002818796.1\| putative dihydroneopterin aldolase FolB [Vibrio cholerae O395], gi\|...	143.0	[0..4]	[120..12]
gi\|21244594, gi\|... - gi\|21244594\|ref\|NP_644176.1\| dihydroneopterin aldolase [Xanthomonas axonopodis pv. citri str. 306], ...	143.0	[0..5]	[120..1]
gi\|84625557, gi\|... - gi\|84625557\|ref\|YP_452929.1\| dihydroneopterin aldolase [Xanthomonas oryzae pv. oryzae MAFF 311018], ...	143.0	[0..5]	[120..1]
gi\|150841262, gi... - gi\|75436806\|ref\|ZP_00733347.1\| dihydroneopterin aldolase [Actinobacillus succinogenes 130Z], gi\|7427...	142.0	[0..6]	[118..3]
gi\|89084762, gi\|... - gi\|89100496\|ref\|ZP_01173357.1\| Dihydroneopterin aldolase [Bacillus sp. NRRL B-14911], gi\|89084762\|gb...	142.0	[0..5]	[120..1]

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Predicted Domain #1

Region A:
Residues: [1-120]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQPAAIIRI KNLRLRTFIG IKEEEINNRQ DIVINVTIHY PADKARTSED INDALNYRTV  60
   61 TKNIIQHVEN NRFSLLEKLT QDVLDIAREH HWVTYAEVEI DKLHALRYAD SVSMTLSWQR 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	1b9lA
Description:	7,8-dihydroneopterin triphosphate epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTP cyclohydrolase I activity	4.32142445441644	bayes_pls_golite062009
cyclohydrolase activity	4.12134839958676	bayes_pls_golite062009
GTP cyclohydrolase activity	3.76376266092452	bayes_pls_golite062009
catalytic activity	2.57832156213163	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.13367928146634	bayes_pls_golite062009
dihydroneopterin aldolase activity	2.05627605013559	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.46072575729571	bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity	0.11818000438771	bayes_pls_golite062009
lyase activity	0.0597333135477298	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: