YRC Public Data Repository - Protein Structure Prediction

Protein:	ILVC_ECOLI
Organism:	Escherichia coli
Length:	491 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ILVC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110807535, gi... - gi\|110807535\|ref\|YP_691054.1\| ketol-acid reductoisomerase [Shigella flexneri 5 str. 8401], gi\|110617...	549.0	[0..1]	[491..46]
gi\|227888641, gi... - gi\|227888641\|ref\|ZP_04006446.1\| Ketol-acid reductoisomerase [Escherichia coli 83972], gi\|227834480\|g... gi\|26250514, gi\|... - gi\|26250514\|ref\|NP_756554.1\| ketol-acid reductoisomerase [Escherichia coli CFT073], gi\|26110944\|gb\|A...	549.0	[0..1]	[491..51]
gi\|91074870, gi\|... - gi\|91213296\|ref\|YP_543282.1\| ketol-acid reductoisomerase [Escherichia coli UTI89], gi\|91074870\|gb\|AB... gi\|237702784, gi... - gi\|237702784\|ref\|ZP_04533265.1\| ketol-acid reductoisomerase [Escherichia sp. 3_2_53FAA], gi\|22690295...	549.0	[0..1]	[491..51]
ILVC_ECOSE - Ketol-acid reductoisomerase OS=Escherichia coli (strain SE11) GN=ilvC PE=3 SV=1 ILVC_ECO81 - Ketol-acid reductoisomerase OS=Escherichia coli O81 (strain ED1a) GN=ilvC PE=3 SV=1 ILVC_ECOL6 - Ketol-acid reductoisomerase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ilvC P... ILVC_ECOSM - Ketol-acid reductoisomerase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=ilvC PE=3 SV=1 gi\|190905353, gi... - gi\|75236530\|ref\|ZP_00720620.1\| COG0059: Ketol-acid reductoisomerase [Escherichia coli F11], gi\|19117... gi\|75234071, gi\|... - gi\|75234071\|ref\|ZP_00718484.1\| COG0059: Ketol-acid reductoisomerase [Escherichia coli E110019], gi\|1... gi\|194412198, gi... - gi\|75209003\|ref\|ZP_00709267.1\| COG0059: Ketol-acid reductoisomerase [Escherichia coli B171], gi\|1944... ILVC_ECOLU - Ketol-acid reductoisomerase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=ilvC PE=3 SV=... ILVC_ECOL6 - Ketol-acid reductoisomerase OS=Escherichia coli O6 GN=ilvC PE=3 SV=3 ILVC_ECO24 - Ketol-acid reductoisomerase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=ilvC PE=3 SV=1 gi\|193066116, gi... - gi\|75255781\|ref\|ZP_00727535.1\| COG0059: Ketol-acid reductoisomerase [Escherichia coli E22], gi\|19306... ILVC_ECOL5 - Ketol-acid reductoisomerase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=ilvC PE=3 SV=1	544.0	[0..1]	[491..1]
gi\|217326533, gi... - gi\|217326533\|ref\|ZP_03442617.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. TW14588],... gi\|208808131, gi... - gi\|208808131\|ref\|ZP_03250468.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4206], ... gi\|15833962, gi\|... - gi\|15833962\|ref\|NP_312735.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|208814177, gi... - gi\|208814177\|ref\|ZP_03255506.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4045], ... gi\|208739819, gi... - gi\|208819696\|ref\|ZP_03260016.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4042], ... ILVC_ECO5E - Ketol-acid reductoisomerase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=ilvC PE=3 SV=1 gi\|189001474, gi... - gi\|189001474\|gb\|EDU70460.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4076], gi\|1... gi\|189373454, gi... - gi\|189373454\|gb\|EDU91870.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC869], gi\|16... gi\|189376790, gi... - gi\|189376790\|gb\|EDU95206.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC508], gi\|16... gi\|195938063 - gi\|195938063\|ref\|ZP_03083445.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4024] gi\|168753668, gi... - gi\|189359024\|gb\|EDU77443.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4401], gi\|1... gi\|168764148, gi... - gi\|189365789\|gb\|EDU84205.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4501], gi\|1... gi\|168768052, gi... - gi\|189362694\|gb\|EDU81113.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4486], gi\|1... gi\|168775678, gi... - gi\|187768844\|gb\|EDU32688.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4196], gi\|1... gi\|209753566, gi... - pir\|\|E86063 ketol-acid reductoisomerase [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|254595173, gi... - gi\|254795773\|ref\|YP_003080610.1\| ketol-acid reductoisomerase, NAD(P)-binding [Escherichia coli O157:... gi\|188014261, gi... - gi\|188014261\|gb\|EDU52383.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4113], gi\|1... gi\|12518635, gi\|... - gi\|15804365\|ref\|NP_290405.1\| ketol-acid reductoisomerase [Escherichia coli O157:H7 EDL933], gi\|12518... ILVC_ECO57 - Ketol-acid reductoisomerase OS=Escherichia coli O157:H7 GN=ilvC PE=3 SV=2	543.0	[0..1]	[491..1]
ILVC_SHIDS - Ketol-acid reductoisomerase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=ilvC PE=3 SV=1	543.0	[0..1]	[491..1]
gi\|146477 - gi\|146477\|gb\|AAA24029.1\| acetohydroxy acid isomeroreductase	543.0	[0..1]	[491..1]
gi\|30064929, gi\|... - gi\|30064929\|ref\|NP_839100.1\| ketol-acid reductoisomerase [Shigella flexneri 2a str. 2457T], gi\|30043... ILVC_SHIFL - Ketol-acid reductoisomerase OS=Shigella flexneri GN=ilvC PE=3 SV=1 gi\|56383982, gi\|... - gi\|56480431\|ref\|NP_709579.2\| ketol-acid reductoisomerase [Shigella flexneri 2a str. 301], gi\|5638398...	543.0	[0..1]	[491..1]
gi\|75230742, gi\|... - gi\|75230742\|ref\|ZP_00717205.1\| COG0059: Ketol-acid reductoisomerase [Escherichia coli B7A], gi\|19116...	542.0	[0..1]	[491..1]

Back

Predicted Domain #1

Region A:
Residues: [1-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANYFNTLNL RQQLAQLGKC RFMGRDEFAD GASYLQGKKV VIVGCGAQGL NQGLNMRDSG  60
   61 LDISYALRKE AIAEKRASWR KATENGFKVG TYEELIPQAD LVINLTPDKQ HSDVVRTVQP 120
  121 LMKDGAALGY SHGFNIVEVG EQIRKDITVV MVAPKCPGTE VREEYKRGFG VPTLIAVHPE 180
  181 NDPKGEGMAI AKAWAAATGG HRAGVLESSF VAEVKSDLMG EQTILCGMLQ AGSLLCFDKL 240
  241 VEEGTDPAYA EKLIQFGWET ITEALKQGGI TLMMDRLSNP AKLRAYALSE QLKEIMAPLF 300
  301 QKHMDDIISG EFSSGMMADW ANDDKKLLTW REETGKTAFE TAPQYEGKIG EQEYFDKGVL 360
  361 MIAMVKAGVE LAFETMVDSG IIEESAYYES LHELPLIANT IARKRLYEMN VVISDTAEYG 420
  421 NYLFSYACVP LLKPFMAELQ PGDLGKAIPE GAVDNGQLRD VNEAIRSHAI EQVGKKLRGY 480
  481 MTDMKRIAVA G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	155.0
Match:	1yrlA
Description:	Escherichia coli ketol-acid reductoisomerase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits