YRC Public Data Repository - Protein Structure Prediction

Protein:	AROC_ECOLI
Organism:	Escherichia coli
Length:	361 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AROC_ECOLI.

Description	E-value	Query Range	Subject Range
AROC_HAHCH - Chorismate synthase OS=Hahella chejuensis (strain KCTC 2396) GN=aroC PE=3 SV=1	634.0	[0..1]	[359..1]
gi\|37680618, gi\|... - gi\|37680618\|ref\|NP_935227.1\| chorismate synthase [Vibrio vulnificus YJ016], gi\|37199366\|dbj\|BAC95198...	632.0	[0..1]	[360..17]
AROC_VIBPA - Chorismate synthase OS=Vibrio parahaemolyticus GN=aroC PE=3 SV=1 AROC_VIBPA - Chorismate synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=aroC PE=3 SV=...	631.0	[0..1]	[360..1]
AROC_MARHV - Chorismate synthase OS=Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8) GN=...	631.0	[0..1]	[359..1]
AROC_VIBVU - Chorismate synthase OS=Vibrio vulnificus (strain CMCP6) GN=aroC PE=3 SV=1 AROC_VIBVU - Chorismate synthase OS=Vibrio vulnificus GN=aroC PE=3 SV=1	630.0	[0..1]	[360..1]
gi\|497783 - gi\|497783\|gb\|AAA21830.1\| 2,3-dihydroxybenzoic acid [Listonella anguillarum]	629.0	[0..1]	[360..12]
gi\|91191679, gi\|... - gi\|91223593\|ref\|ZP_01258858.1\| chorismate synthase [Vibrio alginolyticus 12G01], gi\|91191679\|gb\|EAS7...	629.0	[0..1]	[360..1]

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Predicted Domain #1

Region A:
Residues: [1-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGNTIGQLF RVTTFGESHG LALGCIVDGV PPGIPLTEAD LQHDLDRRRP GTSRYTTQRR  60
   61 EPDQVKILSG VFEGVTTGTS IGLLIENTDQ RSQDYSAIKD VFRPGHADYT YEQKYGLRDY 120
  121 RGGGRSSARE TAMRVAAGAI AKKYLAEKFG IEIRGCLTQM GDIPLDIKDW SQVEQNPFFC 180
  181 PDPDKIDALD ELMRALKKEG DSIGAKVTVV ASGVPAGLGE PVFDRLDADI AHALMSINAV 240
  241 KGVEIGDGFD VVALRGSQNR DEITKDGFQS NHAGGILGGI SSGQQIIAHM ALKPTSSITV 300
  301 PGRTINRFGE EVEMITKGRH DPCVGIRAVP IAEAMLAIVL MDHLLRQRAQ NADVKTDIPR 360
  361 W

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	147.0
Match:	1r52A
Description:	Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
chorismate synthase activity	5.15976990017342	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	4.26558071446785	bayes_pls_golite062009
catalytic activity	1.94308403509017	bayes_pls_golite062009
carbon-oxygen lyase activity	1.59965915025616	bayes_pls_golite062009
lyase activity	1.53765291169529	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: