YRC Public Data Repository - Protein Structure Prediction

Protein:	HCHA_ECOLI
Organism:	Escherichia coli
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HCHA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75510988, gi\|... - gi\|75510988\|ref\|ZP_00733744.1\| COG0693: Putative intracellular protease/amidase [Escherichia coli 53... gi\|75215142, gi\|... - gi\|75215142\|ref\|ZP_00713590.1\| COG0693: Putative intracellular protease/amidase [Escherichia coli E1...	221.0	[0..1]	[283..1]
HCHA_ECOLC - Protein deglycase HchA OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=hchA PE=3 SV=1 HCHA_ECOSM - Protein deglycase HchA OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=hchA PE=3 SV=1 gi\|124532075, gi... - gi\|124532075\|ref\|ZP_01702089.1\| ThiJ/PfpI domain protein [Escherichia coli B], gi\|124498188\|gb\|EAY45... HCHA_ECO81 - Protein deglycase HchA OS=Escherichia coli O81 (strain ED1a) GN=hchA PE=3 SV=1 HCHA_ECOLU - Protein deglycase HchA OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=hchA PE=3 SV=1 gi\|193066638, gi... - gi\|75255227\|ref\|ZP_00727075.1\| COG0693: Putative intracellular protease/amidase [Escherichia coli E2... gi\|190900717, gi... - gi\|75227465\|ref\|ZP_00714232.1\| COG0693: Putative intracellular protease/amidase [Escherichia coli B7... HCHA_ECOHS - Protein deglycase HchA OS=Escherichia coli O9:H4 (strain HS) GN=hchA PE=3 SV=1 HCHA_SHIB3 - Protein deglycase HchA OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=hchA PE=3 SV=1	221.0	[0..1]	[283..1]
gi\|168752200, gi... - gi\|188013897\|gb\|EDU52019.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4113], gi\|168752... gi\|189366017, gi... - gi\|189366017\|gb\|EDU84433.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4501], gi\|168763... gi\|168757598, gi... - gi\|189355439\|gb\|EDU73858.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4401], gi\|168757... gi\|38492413, gi\|... - gi\|38492414\|pdb\|1IZY\|B Chain B, Crystal Structure Of Hsp31, gi\|38492413\|pdb\|1IZY\|A Chain A, Crystal ... HCHA_ECO57 - Protein deglycase HchA OS=Escherichia coli O157:H7 GN=hchA PE=3 SV=3 HCHA_ECO5E - Protein deglycase HchA OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=hchA PE=3 SV=1 gi\|208819638, gi... - gi\|208819638\|ref\|ZP_03259958.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4042], gi\|20... gi\|217318257, gi... - gi\|217328910\|ref\|ZP_03444991.1\| chaperone protein HchA [Escherichia coli O157:H7 str. TW14588], gi\|2... gi\|254593019, gi... - gi\|254793619\|ref\|YP_003078456.1\| Hsp31 molecular chaperone [Escherichia coli O157:H7 str. TW14359], ... gi\|195939272 - gi\|195939272\|ref\|ZP_03084654.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4024] gi\|189376130, gi... - gi\|189376130\|gb\|EDU94546.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC508], gi\|1688017... gi\|13362173, gi\|... - gi\|15831959\|ref\|NP_310732.1\| chaperone protein HchA [Escherichia coli O157:H7 str. Sakai], gi\|133621... gi\|208816695, gi... - gi\|208816695\|ref\|ZP_03257815.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4045], gi\|20... gi\|208810346, gi... - gi\|208810346\|ref\|ZP_03252222.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4206], gi\|20... gi\|168777724, gi... - gi\|187767088\|gb\|EDU30932.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4196], gi\|168777... gi\|168771622, gi... - gi\|189359658\|gb\|EDU78077.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4486], gi\|168771... gi\|168789329, gi... - gi\|189370993\|gb\|EDU89409.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC869], gi\|1687893... gi\|188999309, gi... - gi\|188999309\|gb\|EDU68295.1\| chaperone protein HchA [Escherichia coli O157:H7 str. EC4076], gi\|168783...	220.0	[0..1]	[283..1]
HCHA_ECOSE - Protein deglycase HchA OS=Escherichia coli (strain SE11) GN=hchA PE=3 SV=1 HCHA_ECO24 - Protein deglycase HchA OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=hchA PE=3 SV=1	219.0	[0..1]	[283..1]
gi\|25501075 - gi\|25501075\|pir\|\|H85814 hypothetical protein yedU [imported] - Escherichia coli (strain O157:H7, su... gi\|15802400, gi\|... - gi\|15802400\|ref\|NP_288426.1\| chaperone protein HchA [Escherichia coli O157:H7 EDL933], gi\|12516075\|g...	219.0	[0..1]	[283..1]
gi\|194418062, gi... - gi\|83569517\|ref\|ZP_00920969.1\| COG0693: Putative intracellular protease/amidase [Shigella dysenteria...	219.0	[0..1]	[283..1]
HCHA_ECOK1 - Protein deglycase HchA OS=Escherichia coli O1:K1 / APEC GN=hchA PE=3 SV=1 HCHA_ECOUT - Protein deglycase HchA OS=Escherichia coli (strain UTI89 / UPEC) GN=hchA PE=3 SV=1 HCHA_ECO45 - Protein deglycase HchA OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=hchA PE=3 SV=1	218.0	[0..1]	[283..1]
HCHA_ECOLI - (P31658) Chaperone protein hchA (Hsp31) (EcHsp31)	218.0	[0..2]	[283..1]
HCHA_SHISS - Protein deglycase HchA OS=Shigella sonnei (strain Ss046) GN=hchA PE=3 SV=1	218.0	[0..1]	[282..1]
HCHA_ECOL5 - Protein deglycase HchA OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=hchA PE=3 SV=1 gi\|226900682, gi... - gi\|237705925\|ref\|ZP_04536406.1\| yedU [Escherichia sp. 3_2_53FAA], gi\|226900682\|gb\|EEH86941.1\| yedU [... gi\|227837178, gi... - gi\|227885605\|ref\|ZP_04003410.1\| hydrolase [Escherichia coli 83972], gi\|227837178\|gb\|EEJ47644.1\| hydr... HCHA_ECO7I - Protein deglycase HchA OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=hchA PE=3 SV=1 HCHA_ECOL6 - Chaperone protein hchA OS=Escherichia coli O6 GN=hchA PE=2 SV=2 HCHA_ECOL6 - Protein deglycase HchA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=hchA PE=3 S... gi\|75239142, gi\|... - gi\|75239142\|ref\|ZP_00723119.1\| COG0693: Putative intracellular protease/amidase [Escherichia coli F1...	217.0	[0..1]	[282..1]

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Predicted Domain #1

Region A:
Residues: [1-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVQTSKNPQ VDIAEDNAFF PSEYSLSQYT SPVSDLDGVD YPKPYRGKHK ILVIAADERY  60
   61 LPTDNGKLFS TGNHPIETLL PLYHLHAAGF EFEVATISGL MTKFEYWAMP HKDEKVMPFF 120
  121 EQHKSLFRNP KKLADVVASL NADSEYAAIF VPGGHGALIG LPESQDVAAA LQWAIKNDRF 180
  181 VISLCHGPAA FLALRHGDNP LNGYSICAFP DAADKQTPEI GYMPGHLTWY FGEELKKMGM 240
  241 NIINDDITGR VHKDRKLLTG DSPFAANALG KLAAQEMLAA YAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	1n57A
Description:	HSP31 (HchA; YedU)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.403416821073812	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: