YRC Public Data Repository - Protein Structure Prediction

Protein:	DMSB_ECOLI
Organism:	Escherichia coli
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DMSB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|148655927, gi... - gi\|148655927\|ref\|YP_001276132.1\| 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein [Ro...	201.0	[0..2]	[184..1]
gi\|71282673, gi\|... - gi\|71482494\|ref\|ZP_00662180.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	200.0	[0..3]	[204..22]
gi\|76164515, gi\|... - gi\|76260598\|ref\|ZP_00768231.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	198.0	[0..2]	[184..1]
gi\|56128240, gi\|... - gi\|56413983\|ref\|YP_151058.1\| anaerobic dimethyl sulfoxide reductase chain B [Salmonella enterica sub... gi\|197362906, gi... - gi\|197362906\|ref\|YP_002142543.1\| anaerobic dimethyl sulfoxide reductase chain B [Salmonella enterica...	198.0	[0..1]	[205..1]
gi\|208738266, gi... - gi\|208822781\|ref\|ZP_03263100.1\| anaerobic dimethyl sulfoxide reductase, B subunit [Escherichia coli ... gi\|209399354, gi... - gi\|209399354\|ref\|YP_002269568.1\| anaerobic dimethyl sulfoxide reductase, B subunit [Escherichia coli... gi\|15830234, gi\|... - gi\|15830234\|ref\|NP_309007.1\| anaerobic dimethyl sulfoxide reductase subunit B [Escherichia coli O157... gi\|217325565, gi... - gi\|217325565\|ref\|ZP_03441649.1\| anaerobic dimethyl sulfoxide reductase, B subunit [Escherichia coli ... gi\|25285320, gi\|... - pir\|\|D90751 hypothetical protein ECs0980 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|189376436, gi... - gi\|189376436\|gb\|EDU94852.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|254792095, gi... - gi\|254792095\|ref\|YP_003076932.1\| dimethyl sulfoxide reductase, anaerobic, subunit B [Escherichia col... gi\|15800758, gi\|... - gi\|15800758\|ref\|NP_286772.1\| anaerobic dimethyl sulfoxide reductase subunit B [Escherichia coli O157... gi\|195939558 - gi\|195939558\|ref\|ZP_03084940.1\| anaerobic dimethyl sulfoxide reductase subunit B [Escherichia coli O... gi\|208808514, gi... - gi\|208808514\|ref\|ZP_03250851.1\| anaerobic dimethyl sulfoxide reductase, B subunit [Escherichia coli ... gi\|208815388, gi... - gi\|208815388\|ref\|ZP_03256567.1\| anaerobic dimethyl sulfoxide reductase, B subunit [Escherichia coli ... gi\|189361185, gi... - gi\|189361185\|gb\|EDU79604.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|187768357, gi... - gi\|187768357\|gb\|EDU32201.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|15830234, gi\|... - gi\|15830234\|ref\|NP_309007.1\| anaerobic dimethyl sulfoxide reductase subunit B [Escherichia coli O157... gi\|168783805, gi... - gi\|188998922\|gb\|EDU67908.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|189372640, gi... - gi\|189372640\|gb\|EDU91056.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|168752123, gi... - gi\|188013963\|gb\|EDU52085.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|189355906, gi... - gi\|189355906\|gb\|EDU74325.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC... gi\|168762971, gi... - gi\|189366789\|gb\|EDU85205.1\| dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC...	198.0	[0..1]	[205..1]
gi\|30063104, gi\|... - gi\|30063104\|ref\|NP_837275.1\| putative oxidoreductase, Fe-S subunit [Shigella flexneri 2a str. 2457T]...	197.0	[0..1]	[205..1]
gi\|189339739, gi... - gi\|67918570\|ref\|ZP_00512166.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	197.0	[0..3]	[184..1]
gi\|190907643, gi... - gi\|75240972\|ref\|ZP_00724861.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|110342687, gi... - gi\|110641095\|ref\|YP_668825.1\| anaerobic dimethyl sulfoxide reductase, subunit B [Escherichia coli 53... gi\|227884138, gi... - gi\|227884138\|ref\|ZP_04001943.1\| anaerobic dimethyl sulfoxide reductase chain B [Escherichia coli 839... gi\|26107321, gi\|... - gi\|26246921\|ref\|NP_752961.1\| anaerobic dimethyl sulfoxide reductase chain B [Escherichia coli CFT073...	197.0	[0..1]	[205..1]
gi\|68512319, gi\|... - gi\|68561487\|ref\|ZP_00600782.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	197.0	[0..2]	[184..1]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTQYGFFID SSRCTGCKTC ELACKDYKDL TPEVSFRRIY EYAGGDWQED NGVWHQNVFA  60
   61 YYLSISCNHC EDPACTKVCP SGAMHKREDG FVVVDEDVCI GCRYCHMACP YGAPQYNETK 120
  121 GHMTKCDGCY DRVAEGKKPI CVESCPLRAL DFGPIDELRK KHGDLAAVAP LPRAHFTKPN 180
  181 IVIKPNANSR PTGDTTGYLA NPKEV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.69897
Match:	1kqfB
Description:	Formate dehydrogenase N, iron-sulfur (beta) subunit; Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
formate dehydrogenase activity	10.9674358961972	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	7.27554333181693	bayes_pls_golite062009
iron-sulfur cluster binding	6.49651154487804	bayes_pls_golite062009
metal cluster binding	6.49651154487804	bayes_pls_golite062009
oxidoreductase activity	5.98361135786786	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5.77927347135001	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	5.39747453448396	bayes_pls_golite062009
electron carrier activity	5.05393703018095	bayes_pls_golite062009
NADH dehydrogenase activity	3.13953145151561	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	2.76338281383262	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	2.70037803782769	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.09041948600744	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.80621486978907	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: