YRC Public Data Repository - Protein Structure Prediction

Protein:	BIOD_ECOLI
Organism:	Escherichia coli
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BIOD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|188493435, gi... - gi\|188493435\|ref\|ZP_03000705.1\| dethiobiotin synthase [Escherichia coli 53638], gi\|188488634\|gb\|EDU6... gi\|253774219, gi... - gi\|254287669\|ref\|YP_003053417.1\| dethiobiotin synthetase [Escherichia coli BL21(DE3)], gi\|253976976\|... gi\|242376570, gi... - gi\|251784297\|ref\|YP_002998601.1\| hypothetical protein B21_00762 [Escherichia coli BL21], gi\|24237657... gi\|254160855, gi... - gi\|254160855\|ref\|YP_003043963.1\| dethiobiotin synthetase [Escherichia coli B str. REL606], gi\|253972... gi\|157065933, gi... - gi\|75194930\|ref\|ZP_00705000.1\| COG0132: Dethiobiotin synthetase [Escherichia coli HS], gi\|157160253\|... gi\|83584838 - gi\|83584838\|ref\|ZP_00923497.1\| COG0132: Dethiobiotin synthetase [Escherichia coli 101-1]	179.0	[0..1]	[225..1]
gi\|13360315, gi\|... - gi\|15830110\|ref\|NP_308883.1\| dithiobiotin synthetase [Escherichia coli O157:H7 str. Sakai], gi\|13360... gi\|25389936, gi\|... - pir\|\|H90735 dethiobiotin synthetase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0... gi\|217322302, gi... - gi\|217326081\|ref\|ZP_03442165.1\| dethiobiotin synthase [Escherichia coli O157:H7 str. TW14588], gi\|21... gi\|15800529, gi\|... - gi\|15800529\|ref\|NP_286541.1\| dithiobiotin synthetase [Escherichia coli O157:H7 EDL933], gi\|12513764\|... BIOD1_ECO57 - ATP-dependent dethiobiotin synthetase BioD 1 OS=Escherichia coli O157:H7 GN=bioD1 PE=3 SV=3	177.0	[0..1]	[225..1]
gi\|74311322, gi\|... - gi\|74311322\|ref\|YP_309741.1\| dithiobiotin synthetase [Shigella sonnei Ss046], gi\|73854799\|gb\|AAZ8750... gi\|75255329 - gi\|75255329\|ref\|ZP_00727158.1\| COG0132: Dethiobiotin synthetase [Escherichia coli E22] gi\|110804779, gi... - gi\|110804779\|ref\|YP_688299.1\| dithiobiotin synthetase [Shigella flexneri 5 str. 8401], gi\|110614327\|... gi\|75235856 - gi\|75235856\|ref\|ZP_00720011.1\| COG0132: Dethiobiotin synthetase [Escherichia coli E110019] gi\|218553361, gi... - gi\|218553361\|ref\|YP_002386274.1\| dithiobiotin synthetase [Escherichia coli IAI1], gi\|218360129\|emb\|C... gi\|191168428, gi... - gi\|75228356\|ref\|ZP_00715004.1\| COG0132: Dethiobiotin synthetase [Escherichia coli B7A], gi\|191168428... gi\|218694251, gi... - gi\|218694251\|ref\|YP_002401918.1\| dithiobiotin synthetase [Escherichia coli 55989], gi\|218350983\|emb\|... gi\|75189819, gi\|... - gi\|75189819\|ref\|ZP_00703086.1\| COG0132: Dethiobiotin synthetase [Escherichia coli E24377A], gi\|15715... gi\|209918022, gi... - gi\|209918022\|ref\|YP_002292106.1\| dithiobiotin synthetase [Escherichia coli SE11], gi\|209911281\|dbj\|B...	177.0	[0..1]	[225..1]
gi\|213855829 - gi\|213855829\|ref\|ZP_03384069.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar... gi\|214000513 - gi\|214000513\|ref\|ZP_03411248.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar... gi\|29138136, gi\|... - gi\|29142505\|ref\|NP_805847.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar Ty... gi\|16759722 - gi\|16759722\|ref\|NP_455339.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar Ty... gi\|207856235, gi... - gi\|207856235\|ref\|YP_002242886.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serova... gi\|213052116 - gi\|213052116\|ref\|ZP_03344994.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar... gi\|213424805 - gi\|213424805\|ref\|ZP_03357555.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar... gi\|213647608 - gi\|213647608\|ref\|ZP_03377661.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serovar... BIOD_SALTI - Dethiobiotin synthetase OS=Salmonella typhi GN=bioD PE=3 SV=1 gi\|197936587, gi... - gi\|198242071\|ref\|YP_002214762.1\| dethiobiotin synthase [Salmonella enterica subsp. enterica serovar ... gi\|205271837, gi... - gi\|205352056\|ref\|YP_002225857.1\| dithiobiotin synthetase [Salmonella enterica subsp. enterica serova... BIOD1_SALTI - ATP-dependent dethiobiotin synthetase BioD 1 OS=Salmonella typhi GN=bioD1 PE=3 SV=1	177.0	[0..1]	[225..1]
gi\|56383276, gi\|... - gi\|56479725\|ref\|NP_706656.2\| dithiobiotin synthetase [Shigella flexneri 2a str. 301], gi\|56383276\|gb... gi\|30062263, gi\|... - gi\|30062263\|ref\|NP_836434.1\| dithiobiotin synthetase [Shigella flexneri 2a str. 2457T], gi\|30040508\|...	177.0	[0..1]	[225..1]
gi\|187427454, gi... - gi\|75178005\|ref\|ZP_00698067.1\| COG0132: Dethiobiotin synthetase [Shigella boydii BS512], gi\|18773046...	176.0	[0..1]	[225..1]
gi\|81244636, gi\|... - gi\|82543225\|ref\|YP_407172.1\| dithiobiotin synthetase [Shigella boydii Sb227], gi\|81244636\|gb\|ABB6534...	176.0	[0..1]	[225..1]
gi\|75208778 - gi\|75208778\|ref\|ZP_00709067.1\| COG0132: Dethiobiotin synthetase [Escherichia coli B171]	175.0	[0..1]	[222..1]
gi\|82776152, gi\|... - gi\|82776152\|ref\|YP_402499.1\| dithiobiotin synthetase [Shigella dysenteriae Sd197], gi\|81240300\|gb\|AB...	175.0	[0..1]	[225..1]
BIOD1_SALTY - ATP-dependent dethiobiotin synthetase BioD 1 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC... BIOD_SALTY, BIOD... - Dethiobiotin synthetase OS=Salmonella typhimurium GN=bioD PE=3 SV=1, ATP-dependent dethiobiotin synt... gi\|194736665, gi... - gi\|194736665\|ref\|YP_002113890.1\| dethiobiotin synthase [Salmonella enterica subsp. enterica serovar ... gi\|168236721, gi... - gi\|197290155\|gb\|EDY29512.1\| dethiobiotin synthase [Salmonella enterica subsp. enterica serovar Schwa... gi\|204321093, gi... - gi\|204930099\|ref\|ZP_03221120.1\| dethiobiotin synthase [Salmonella enterica subsp. enterica serovar J... gi\|199602616, gi... - gi\|200390171\|ref\|ZP_03216782.1\| dethiobiotin synthase [Salmonella enterica subsp. enterica serovar V... lcl\|NC_016856.1_... - [gene=bioD_1] [protein=dithiobiotin synthetase] [protein_id=YP_005236516.1] [location=863437..864123... BIOD_SALTY - Dethiobiotin synthetase OS=Salmonella typhimurium GN=bioD PE=3 SV=1 gi\|197262893, gi... - gi\|197262893\|ref\|ZP_03162967.1\| dethiobiotin synthase [Salmonella enterica subsp. enterica serovar S...	175.0	[0..1]	[225..1]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRYFVTGT DTEVGKTVAS CALLQAAKAA GYRTAGYKPV ASGSEKTPEG LRNSDALALQ  60
   61 RNSSLQLDYA TVNPYTFAEP TSPHIISAQE GRPIESLVMS AGLRALEQQA DWVLVEGAGG 120
  121 WFTPLSDTFT FADWVTQEQL PVILVVGVKL GCINHAMLTA QVIQHAGLTL AGWVANDVTP 180
  181 PGKRHAEYMT TLTRMIPAPL LGEIPWLAEN PENAATGKYI NLALL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	1a82A
Description:	DETHIOBIOTIN SYNTHETASE FROM ESCHERICHIA COLI, COMPLEX WITH SUBSTRATES ATP AND DIAMINOPELARGONIC ACID
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: