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View Structure Prediction Details

Protein: gi|7448452
Organism: Synechocystis sp.
Length: 452 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7448452.

Description E-value Query
Range
Subject
Range
gi|25305582 - pir||AD1894 serine proteinase [imported] - Nostoc sp. (strain PCC 7120)
gi|17228197, gi|... - gi|17228197|ref|NP_484745.1| serine proteinase [Nostoc sp. PCC 7120], gi|17130047|dbj|BAB72659.1| se...
294.0 [0..21] [448..11]
gi|67922820, gi|... - gi|67922820|ref|ZP_00516319.1| Peptidase S1, chymotrypsin:PDZ/DHR/GLGF [Crocosphaera watsonii WH 850...
291.0 [0..22] [448..1]
gi|75704531, gi|... - gi|75910806|ref|YP_325102.1| peptidase S1 and S6, chymotrypsin/Hap [Anabaena variabilis ATCC 29413],...
290.0 [0..25] [452..15]
gi|23127196 - gi|23127196|ref|ZP_00109071.1| COG0265: Trypsin-like serine proteases, typically periplasmic, contai...
283.0 [0..42] [448..25]
gi|86555900, gi|... - gi|86607358|ref|YP_476121.1| S1C family peptidase [Synechococcus sp. JA-3-3Ab], gi|86555900|gb|ABD00...
gi|86607358 - gi|86607358|ref|YP_476121.1| peptidase, S1C (protease Do) family [Cyanobacteria bacterium Yellowston...
276.0 [0..52] [447..8]
gi|85721301, gi|... - gi|85858210|ref|YP_460412.1| trypsin-like serine protease [Syntrophus aciditrophicus SB], gi|8572130...
272.0 [0..46] [449..5]
gi|86608125 - gi|86608125|ref|YP_476887.1| peptidase, S1C (protease Do) family [Cyanobacteria bacterium Yellowston...
gi|86608125, gi|... - gi|86608125|ref|YP_476887.1| S1C family peptidase [Synechococcus sp. JA-2-3B'a(2-13)], gi|86556667|g...
271.0 [0..47] [447..5]
gi|78224552, gi|... - gi|78224552|ref|YP_386299.1| peptidase S1C, Do [Geobacter metallireducens GS-15], gi|78195807|gb|ABB...
271.0 [0..103] [448..19]
gi|71677069, gi|... - gi|71677069|ref|ZP_00674808.1| Peptidase S1, chymotrypsin:PDZ/DHR/GLGF [Trichodesmium erythraeum IMS...
270.0 [0..44] [448..7]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAQAVFPIA PHRADFFPRF VLSNSSANKC HQAMKDVSLH SPKQTPSKIS LAYLGLVLVG  60
   61 MGIGAGGTFV LTNPQWADHL TNNSVISPLV TNQSIAPANE SLATNLQS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [109-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLSPREPSNF VVDVVESTGP AVVRINAQKT VKSQVPQAFN DPFLQRFFGS QMPPMPNERV  60
   61 QRGTGSGFIV SNDGKIFTNA HVVDGADEVT VTLKDGRSFP GRVMGSDPST DVAVVKIEAG 120
  121 DLPTVALGDS DHLQVGEWAI AIGNPLGLDN TVTTGILSAT GRRSADIGVP DKRVEFIQTD 180
  181 AAINPGNSGG PLLNADGQVI GMNTAIIQNA QGIGFAIPIN KAQEIAQQLI ATGKVEHAYL 240
  241 GIQMVTMTPE LQSQIRQETG MNIPVDKGVV IMQVMPNSPA AIAKLEQGDV LQSLQGQPVE 300
  301 NAEQVQSLVG KLAVGDEVEL GILRNGQQQN LTVTIGALPS APPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1ky9A
Description: Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.45528883298499 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.08053412162226 bayes_pls_golite062009
endopeptidase activity 3.78841204092284 bayes_pls_golite062009
serine-type peptidase activity 3.58347664461084 bayes_pls_golite062009
serine hydrolase activity 3.58106288341801 bayes_pls_golite062009
serine-type endopeptidase activity 3.36658782366155 bayes_pls_golite062009
hydrolase activity 2.78416408149092 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle