YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30254854, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	425 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30254854, gi|....

Description	E-value	Query Range	Subject Range
gi\|113868203, gi... - gi\|113868203\|ref\|YP_726692.1\| isocitrate lyase [Ralstonia eutropha H16], gi\|113526979\|emb\|CAJ93324.1...	0.0	[2..425]	[3..426]
gi\|73541649, gi\|... - gi\|73541649\|ref\|YP_296169.1\| isocitrate lyase [Ralstonia eutropha JMP134], gi\|72119062\|gb\|AAZ61325.1...	0.0	[2..425]	[3..426]
gi\|93354179, gi\|... - gi\|94310327\|ref\|YP_583537.1\| isocitrate lyase [Ralstonia metallidurans CH34], gi\|93354179\|gb\|ABF0826...	0.0	[2..425]	[4..427]
gi\|89205666, gi\|... - gi\|89205666\|ref\|ZP_01184234.1\| Isocitrate lyase [Bacillus weihenstephanensis KBAB4], gi\|89156460\|gb\|...	0.0	[1..425]	[1..425]
gi\|42736223, gi\|... - gi\|42780304\|ref\|NP_977551.1\| isocitrate lyase [Bacillus cereus ATCC 10987], gi\|42736223\|gb\|AAS40159....	0.0	[1..425]	[1..425]
gi\|89088458, gi\|... - gi\|89097078\|ref\|ZP_01169969.1\| isocitrate lyase [Bacillus sp. NRRL B-14911], gi\|89088458\|gb\|EAR67568...	0.0	[1..424]	[1..424]
gi\|89201743, gi\|... - gi\|89201743\|ref\|ZP_01180479.1\| Isocitrate lyase [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|89...	0.0	[1..425]	[1..425]
gi\|56419211, gi\|... - gi\|56419211\|ref\|YP_146529.1\| isocitrate lyase [Geobacillus kaustophilus HTA426], gi\|56379053\|dbj\|BAD...	0.0	[4..424]	[6..426]
gi\|49330584, gi\|... - gi\|49479028\|ref\|YP_035365.1\| isocitrate lyase [Bacillus thuringiensis serovar konkukian str. 97-27],...	0.0	[1..425]	[1..425]
gi\|56477970, gi\|... - gi\|56477970\|ref\|YP_159559.1\| isocitrate lyase [Aromatoleum aromaticum EbN1], gi\|56314013\|emb\|CAI0865...	0.0	[2..423]	[5..432]

Back

Predicted Domain #1

Region A:
Residues: [1-425]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNERIEKLQ ESWELDTRWK GITRPYSAED VIRLRGSIDI EHTLARRGAE KLWASLHTED  60
   61 YINALGALTG NQAMQQVKAG LKAIYLSGWQ VAADANLSGH MYPDQSLYPA NSVPAVVKRI 120
  121 NQTLQRADQI QHMEGSGDTD YFVPIVADAE AGFGGQLNVF ELMKGMIEAG ASGVHFEDQL 180
  181 SSEKKCGHLG GKVLLPTQTA VRNLISARLA ADVMGVPTII VARTDADAAD LITSDIDPVD 240
  241 KAFITGERTP EGFYRTKAGL DQAIARGLAY APYADLVWCE TSEPNLEDAK RFADAIHKEH 300
  301 PGKLLAYNCS PSFNWKQKLD EKTIASFQKE IASYGYKFQF VTLAGFHSLN YGMFELARGY 360
  361 KERGMAAYSE LQQAEFAAEK HGYSATRHQR EVGTGYFDEV AQVITGGTSS TTALKGSTEE 420
  421 AQFTK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	155.0
Match:	1igwA
Description:	Isocitrate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.59838799615646	bayes_pls_golite062009
methylisocitrate lyase activity	2.06824730122158	bayes_pls_golite062009
3-methyl-2-oxobutanoate hydroxymethyltransferase activity	0.987472653142222	bayes_pls_golite062009
isocitrate lyase activity	0.714624467380094	bayes_pls_golite062009
transferase activity	0.368032846714701	bayes_pls_golite062009
lyase activity	0.0456521871650777	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: