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View Structure Prediction Details

Protein: nhr-31
Organism: Caenorhabditis elegans
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-31.

Description E-value Query
Range
Subject
Range
gi|10197985 - gi|10197985|gb|AAG15127.1| nuclear receptor NHR-31 [Caenorhabditis elegans]
379.0 [0..1] [544..52]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGDLRTSGA TSSSGPATSY IIRPSDKQPT VSSGGSQNGD SVCAVCGDGI AKLHYGVLAC  60
   61 YGCKGFFRRT LTGKYRYACR FSNNCIVDKF QRNSCRYCRF QRCIQAGMDP KAVRPDRDQT 120
  121 GKQKVPRIKK KQID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [135-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EELLNHMMRL QGDDWSRKLP VETRILLMQL MSIEDKVVKG DNNMSAQNTA KDPKSISLRE  60
   61 MFESKPALDG RRMEIGYEPF RMARTEELGV IAHRRAIAAV DWVDSLTEIA DAVDTEDKVA 120
  121 LVKSCYSPLT IFNFSARTAQ NTKNPDILCL CSHSFVPRRL PPEFNETNHL SNFLIDRTLN 180
  181 ELVAPLRKLN LKEEEIVPLK AIIILNPNAK GLSEHARHAI SELRDKVQDM LFQIVKELHP 240
  241 IYSASSRFGN LLLLLPTITT LSGLMSENMH FCQALGGRAS GDNLLAEMFG DRTF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.39794
Match: 2gl8A
Description: No description for 2gl8A was found.

Predicted Domain #3
Region A:
Residues: [429-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDQLISSSIS PPLFENPAEI CLESISPPMS DRRFVRRVDV ATQTNDDLLS SGPYLPHSNS  60
   61 CSSMLNAGYS PPMLSTSPFP LLDDNDSAFQ NDISLTELNG CEEFFSQLMD QPIIDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle