YRC Public Data Repository - Protein Structure Prediction

Protein:	TRPF_THEMA
Organism:	Thermotoga maritima MSB8
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPF_THEMA.

Description	E-value	Query Range	Subject Range
gi\|8569670, gi\|8... - gi\|8569670\|pdb\|1DL3\|B Chain B, Crystal Structure Of Mutually Generated Monomers Of Dimeric Phosphori...	269.0	[0..1]	[205..1]
TRPF_GEOSL - N-(5'-phosphoribosyl)anthranilate isomerase OS=Geobacter sulfurreducens GN=trpF PE=3 SV=1 TRPF_GEOSL - N-(5'-phosphoribosyl)anthranilate isomerase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 121...	256.0	[0..1]	[204..1]
TRPF_GEOMG - N-(5'-phosphoribosyl)anthranilate isomerase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 ...	256.0	[0..1]	[203..1]
TRPF_GEOUR - N-(5'-phosphoribosyl)anthranilate isomerase OS=Geobacter uraniireducens (strain Rf4) GN=trpF PE=3 SV...	248.0	[0..1]	[205..1]
gi\|254493168, gi... - gi\|254493168\|ref\|ZP_05106339.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae 1... gi\|240127653 - gi\|240127653\|ref\|ZP_04740314.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae S... gi\|240125198 - gi\|240125198\|ref\|ZP_04738084.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae S... gi\|240080153 - gi\|240080153\|ref\|ZP_04724696.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae F... TRPF_NEIG1 - N-(5'-phosphoribosyl)anthranilate isomerase OS=Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) ... gi\|240013573 - gi\|240013573\|ref\|ZP_04720486.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae D... gi\|239998448 - gi\|239998448\|ref\|ZP_04718372.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae 3... gi\|240122947 - gi\|240122947\|ref\|ZP_04735903.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae P... gi\|240120642 - gi\|240120642\|ref\|ZP_04733604.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae P... gi\|240115107 - gi\|240115107\|ref\|ZP_04729169.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae P... gi\|240112367 - gi\|240112367\|ref\|ZP_04726857.1\| N-(5'-phosphoribosyl)anthranilate isomerase [Neisseria gonorrhoeae M...	246.0	[0..3]	[205..5]
TRPF_PELPD - N-(5'-phosphoribosyl)anthranilate isomerase OS=Pelobacter propionicus (strain DSM 2379) GN=trpF PE=3...	246.0	[0..1]	[203..1]
gi\|95109835 - gi\|95109835\|emb\|CAK14540.1\| N-(5'-phosphoribosyl)anthranilate isomerase (PRAI) [Pseudomonas entomoph... TRPF_PSEE4 - N-(5'-phosphoribosyl)anthranilate isomerase OS=Pseudomonas entomophila (strain L48) GN=trpF PE=3 SV=...	246.0	[0..2]	[203..4]
TRPF_NEIMA - N-(5'-phosphoribosyl)anthranilate isomerase OS=Neisseria meningitidis serogroup A GN=trpF PE=3 SV=1 gi\|11268653 - gi\|11268653\|pir\|\|E81935 probable phosphoribosylanthranilate isomerase (EC 5.3.1.24) NMA0890 [importe... TRPF_NEIMA - N-(5'-phosphoribosyl)anthranilate isomerase OS=Neisseria meningitidis serogroup A / serotype 4A (str...	244.0	[0..3]	[205..5]
TRPF_GEODF - N-(5'-phosphoribosyl)anthranilate isomerase OS=Geobacter daltonii (strain DSM 22248 / JCM 15807 / FR...	243.0	[0..1]	[203..1]
TRPF_PSEPF - N-(5'-phosphoribosyl)anthranilate isomerase OS=Pseudomonas fluorescens (strain Pf0-1) GN=trpF PE=3 S...	240.0	[0..2]	[203..4]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRVKICGIT NLEDALFSVE SGADAVGFVF YPKSKRYISP EDARRISVEL PPFVFRVGVF  60
   61 VNEEPEKILD VASYVQLNAV QLHGEEPIEL CRKIAERILV IKAVGVSNER DMERALNYRE 120
  121 FPILLDTKTP EYGGSGKTFD WSLILPYRDR FRYLVLSGGL NPENVRSAID VVRPFAVDVS 180
  181 SGVEAFPGKK DHDSIKMFIK NAKGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.0
Match:	1lbmA
Description:	N-(5'phosphoribosyl)antranilate isomerase, PRAI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tryptophan synthase activity	2.99898167480072	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	2.98379231184807	bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity	2.57188946638955	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
carbon-carbon lyase activity	1.80077901589281	bayes_pls_golite062009
carboxy-lyase activity	1.32677036501434	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.567370625225674	bayes_pls_golite062009
lyase activity	0.258652421339738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: