YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261507, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	194 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261507, gi|....

Description	E-value	Query Range	Subject Range
HIS5B_ARATH - Imidazoleglycerol-phosphate dehydratase 2, chloroplastic OS=Arabidopsis thaliana GN=HISN5B PE=1 SV=2	4.0E-90	[2..194]	[76..269]
gi\|75909492, gi\|... - gi\|75909492\|ref\|YP_323788.1\| imidazoleglycerol-phosphate dehydratase [Anabaena variabilis ATCC 29413...	8.0E-89	[2..194]	[41..234]
HIS7_AMIAM - Imidazoleglycerol-phosphate dehydratase OS=Aminomonas aminovorus GN=hisB PE=3 SV=1	1.0E-88	[1..194]	[1..195]
gi\|3982576, gi\|1... - gi\|3982576\|gb\|AAC83458.1\| imidazoleglycerol phosphate dehydratase [Thlaspi goesingense], pir\|\|T48893...	1.0E-88	[2..194]	[78..271]
gi\|91070624 - gi\|91070624\|gb\|ABE11523.1\| imidazoleglycerol-phosphate dehydratase [uncultured Prochlorococcus marin...	2.0E-88	[1..194]	[21..215]
HIS7_CLOTH - Imidazoleglycerol-phosphate dehydratase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / ... gi\|196252973, gi... - gi\|196252973\|ref\|ZP_03151618.1\| Imidazoleglycerol-phosphate dehydratase [Clostridium thermocellum DS...	3.0E-88	[2..194]	[3..195]
HIS7_METFK - Imidazoleglycerol-phosphate dehydratase OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM...	4.0E-88	[1..194]	[4..198]
HIS7_CHESB - Imidazoleglycerol-phosphate dehydratase OS=Chelativorans sp. (strain BNC1) GN=hisB PE=3 SV=1	4.0E-88	[2..194]	[7..200]
HIS7_NEIMF - Imidazoleglycerol-phosphate dehydratase OS=Neisseria meningitidis serogroup C / serotype 2a (strain ... gi\|254672362 - gi\|254672362\|emb\|CBA05587.1\| Imidazoleglycerol-phosphate dehydratase [Neisseria meningitidis serogro... HIS7_NEIMA - Imidazoleglycerol-phosphate dehydratase OS=Neisseria meningitidis serogroup A GN=hisB PE=3 SV=1 gi\|254668894, gi... - gi\|254805352\|ref\|YP_003083573.1\| Imidazoleglycerol-phosphate dehydratase [Neisseria meningitidis], g... HIS7_NEIMB - Imidazoleglycerol-phosphate dehydratase OS=Neisseria meningitidis serogroup B GN=hisB PE=3 SV=1 gi\|11353753 - pir\|\|G81067 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) NMA1772 [imported] - Neisseria men... HIS7_NEIMA - Imidazoleglycerol-phosphate dehydratase OS=Neisseria meningitidis serogroup A / serotype 4A (strain ... HIS7_NEIM0 - Imidazoleglycerol-phosphate dehydratase OS=Neisseria meningitidis serogroup C (strain 053442) GN=his... HIS7_NEIMB - Imidazoleglycerol-phosphate dehydratase OS=Neisseria meningitidis serogroup B (strain MC58) GN=hisB ...	6.0E-88	[2..194]	[110..303]

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Predicted Domain #1

Region A:
Residues: [1-194]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRESSQIRET TETKIKLSLQ LDEGKNVSVQ TGVGFFDHML TLFARHGRFG LQVEAEGDVF  60
   61 VDAHHTVEDV GIVLGNCLKE ALQNKEGINR YGSAYVPMDE SLGFVAIDIS GRSYIVFQGE 120
  121 LTNPKLGDFD TELTEEFFRA VAHAANITLH ARILYGSNTH HKIEALFKAF GRALREAVER 180
  181 NAHITGVNST KGML

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.69897
Match:	2f1dA
Description:	X-Ray Structure of imidazoleglycerol-phosphate dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate dehydratase activity	1.6337728630325	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
nucleic acid binding	0.369771518688522	bayes_pls_golite062009
structural constituent of ribosome	0.325699575011026	bayes_pls_golite062009
transcription regulator activity	0.212099606954236	bayes_pls_golite062009
structural molecule activity	2.19428886088058E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: