YRC Public Data Repository - Protein Structure Prediction

Protein:	GCSH_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	130 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCSH_COXBU.

Description	E-value	Query Range	Subject Range
gi\|85719356 - gi\|85719356\|gb\|ABC75361.1\| 2-oxo acid dehydrogenase, lipoyl-binding site [Medicago truncatula]	140.0	[0..2]	[129..25]
gi\|78064801, gi\|... - gi\|78064801\|ref\|YP_367570.1\| glycine cleavage H-protein [Burkholderia sp. 383], gi\|77965546\|gb\|ABB06...	137.0	[0..1]	[126..29]
GCSH_SHEAM - Glycine cleavage system H protein OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=gcvH PE...	136.0	[0..1]	[129..1]
GCSH_ALTMD - Glycine cleavage system H protein OS=Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 2... GCSH_ALTMD - Glycine cleavage system H protein OS=Alteromonas macleodii (strain DSM 17117 / Deep ecotype) GN=gcvH...	135.0	[0..1]	[129..1]
gi\|215701162, gi... - gi\|52076539\|dbj\|BAD45416.1\| putative glycine decarboxylase complex H-protein [Oryza sativa Japonica ... gi\|218198716 - gi\|218198716\|gb\|EEC81143.1\| hypothetical protein OsI_24045 [Oryza sativa Indica Group]	134.0	[0..2]	[129..30]
GCSH_SHELP - Glycine cleavage system H protein OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=gcvH PE=3 S...	134.0	[0..1]	[129..1]
GCSH_PHOLL - Glycine cleavage system H protein OS=Photorhabdus luminescens subsp. laumondii GN=gcvH PE=3 SV=1 GCSH_PHOLL - Glycine cleavage system H protein OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / C...	133.0	[0..1]	[129..1]
gi\|886868, gi\|13... - gi\|886868\|emb\|CAA88734.1\| H-protein precursor of glycine cleavage system [Flaveria trinervia], pir\|\|...	132.0	[0..2]	[129..32]

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Predicted Domain #1

Region A:
Residues: [1-130]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEFPAELYY SKNHEWMRKE SDETFTVGIT DHAQEQLGDL VFVELPETNI HVDAGDEVAV  60
   61 VESVKTAADV YSPLSGKVIE INNALENEPA TVNRDPYGDG WLYRITIDDE KELNDLLDAD 120
  121 GYQTLIEAES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.0
Match:	1onlA
Description:	Crystal structure of Thermus thermophilus HB8 H-protein of the glycine cleavage system
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminomethyltransferase activity	7.15454688996532	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	6.56199545993139	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	6.56199545993139	bayes_pls_golite062009
acetyl-CoA carboxylase activity	2.30995434688093	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	1.93346020821958	bayes_pls_golite062009
CoA carboxylase activity	1.92420834470262	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	1.62422217856347	bayes_pls_golite062009
catalytic activity	1.39099902011318	bayes_pls_golite062009
ligase activity	0.56894584941056	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: