YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29142880, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Length:	483 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29142880, gi|....

Description	E-value	Query Range	Subject Range
gi\|48784618, gi\|... - gi\|91777235\|ref\|YP_552443.1\| 2-methylcitrate dehydratase [Burkholderia xenovorans LB400], gi\|9168989...	0.0	[1..483]	[1..483]
gi\|75238481, gi\|... - gi\|75238481\|ref\|ZP_00722475.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|110640613, gi... - gi\|110640613\|ref\|YP_668341.1\| 2-methylcitrate dehydratase [Escherichia coli 536], gi\|110342205\|gb\|AB...	0.0	[1..483]	[1..483]
gi\|83586370, gi\|... - gi\|83586370\|ref\|ZP_00925005.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|218430718, gi... - gi\|218703621\|ref\|YP_002411140.1\| 2-methylcitrate dehydratase [Escherichia coli UMN026], gi\|218430718... PRPD_ECOLI - 2-methylcitrate dehydratase (EC 4.2.1.79) - Escherichia coli gi\|89107206, gi\|... - gi\|89107206\|ref\|AP_000986.1\| 2-methylcitrate dehydratase [Escherichia coli str. K-12 substr. W3110],... EG13603 - 2-methylcitrate dehydratase / 2-Methylcitrate dehydratase, 2-methylisocitrate hydratase; propionate ... EG13603 - 2-methylcitrate dehydratase / 2-Methylcitrate dehydratase, 2-methylisocitrate hydratase; propionate ...	0.0	[1..483]	[1..483]
gi\|157080292, gi... - gi\|75189408\|ref\|ZP_00702675.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|209910808, gi... - gi\|209917549\|ref\|YP_002291633.1\| 2-methylcitrate dehydratase [Escherichia coli SE11], gi\|209910808\|d... gi\|218552900, gi... - gi\|218552900\|ref\|YP_002385813.1\| 2-methylcitrate dehydratase [Escherichia coli IAI1], gi\|218359668\|e... gi\|218693797, gi... - gi\|218693797\|ref\|YP_002401464.1\| 2-methylcitrate dehydratase [Escherichia coli 55989], gi\|218350529\|... gi\|192928984, gi... - gi\|75257640\|ref\|ZP_00729131.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|191165745, gi... - gi\|75231107\|ref\|ZP_00717529.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|194427548, gi... - gi\|75211136\|ref\|ZP_00711243.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|157159851, gi... - gi\|75194558\|ref\|ZP_00704628.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E...	0.0	[1..483]	[1..483]
gi\|192958035, gi... - gi\|75237259\|ref\|ZP_00721306.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E...	0.0	[1..483]	[1..483]
gi\|91209411, gi\|... - gi\|91209411\|ref\|YP_539397.1\| 2-methylcitrate dehydratase [Escherichia coli UTI89], gi\|91070985\|gb\|AB... gi\|117622616, gi... - gi\|117622616\|ref\|YP_851529.1\| 2-methylcitrate dehydratase [Escherichia coli APEC O1], gi\|115511740\|g... gi\|237707663, gi... - gi\|237707663\|ref\|ZP_04538144.1\| 2-methylcitrate dehydratase [Escherichia sp. 3_2_53FAA], gi\|22689887... gi\|26246349, gi\|... - gi\|26246349\|ref\|NP_752388.1\| 2-methylcitrate dehydratase [Escherichia coli CFT073], gi\|26106747\|gb\|A... gi\|227884648, gi... - gi\|227884648\|ref\|ZP_04002453.1\| 2-methylcitrate dehydratase [Escherichia coli 83972], gi\|227838383\|g... gi\|218557262, gi... - gi\|218557262\|ref\|YP_002390175.1\| 2-methylcitrate dehydratase [Escherichia coli S88], gi\|218364031\|em...	0.0	[1..483]	[1..483]
gi\|36786848, gi\|... - gi\|37527413\|ref\|NP_930757.1\| 2-methylcitrate dehydratase [Photorhabdus luminescens subsp. laumondii ...	0.0	[1..483]	[1..483]
gi\|13359844, gi\|... - gi\|15829641\|ref\|NP_308414.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|209159921, gi... - gi\|209398521\|ref\|YP_002268971.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4115],... gi\|217322854, gi... - gi\|217326633\|ref\|ZP_03442717.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. TW14588],... gi\|195937833 - gi\|195937833\|ref\|ZP_03083215.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4024] gi\|208728101, gi... - gi\|208808300\|ref\|ZP_03250637.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4206], ... gi\|208732387, gi... - gi\|208815739\|ref\|ZP_03256918.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4045], ... gi\|254791512, gi... - gi\|254791512\|ref\|YP_003076349.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. TW14359]... gi\|208823186, gi... - gi\|208823186\|ref\|ZP_03263504.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4042], ... gi\|187769073, gi... - gi\|187769073\|gb\|EDU32917.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4196], gi\|1... gi\|188999853, gi... - gi\|188999853\|gb\|EDU68839.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4076], gi\|1... gi\|189371708, gi... - gi\|189371708\|gb\|EDU90124.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC869], gi\|16... gi\|189377830, gi... - gi\|189377830\|gb\|EDU96246.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC508], gi\|16... gi\|188016477, gi... - gi\|188016477\|gb\|EDU54599.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4113], gi\|1... gi\|168755912, gi... - gi\|189356959\|gb\|EDU75378.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4401], gi\|1... gi\|168762004, gi... - gi\|189367672\|gb\|EDU86088.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4501], gi\|1... gi\|168769713, gi... - gi\|189361316\|gb\|EDU79735.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4486], gi\|1... PRPD_ECO57 - 2-methylcitrate dehydratase OS=Escherichia coli O157:H7 GN=prpD PE=3 SV=3 gi\|209744756, gi... - pir\|\|F85527 hypothetical protein prpD [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15800062, gi\|... - gi\|15800062\|ref\|NP_286074.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 EDL933], gi\|12513...	0.0	[1..483]	[1..483]
PRPD_SALTY - 2-methylcitrate dehydratase OS=Salmonella typhimurium GN=prpD PE=3 SV=2 PRPD_SALTY - 2-methylcitrate dehydratase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=prpD ... PRPD_SALTY - 2-methylcitrate dehydratase OS=Salmonella typhimurium GN=prpD PE=3 SV=2 gi\|205329549, gi... - gi\|205329549\|gb\|EDZ16313.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica serovar... gi\|168819032, gi... - gi\|205344121\|gb\|EDZ30885.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica serovar... lcl\|NC_016856.1_... - [gene=prpD] [protein=2-methylcitrate dehydratase] [protein_id=YP_005236049.1] [location=420889..4223...	0.0	[1..483]	[1..483]
gi\|197363395, gi... - gi\|197363395\|ref\|YP_002143032.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica se... gi\|56128731, gi\|... - gi\|56414474\|ref\|YP_151549.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica serova...	0.0	[1..483]	[1..483]

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Predicted Domain #1

Region A:
Residues: [1-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAHISNVRP DFDREIVDIV DYVMNYEITS KVAYDTAHYC LLDTLGCGLE ALEYPACKKL  60
   61 LGPIVPGTVV PNGARVPGTQ FQLDPVQAAF NISAMIRWLD FNDTWLAAEW GHPSDNLGGI 120
  121 LATADWLSRN AVAAGKAPLT MKQVLSGMIK AHEIQGCIAL ENAFNRVGLD HVLLVKVAST 180
  181 AVVAEMLGLT RDEILNAVSL AWVDGQSLRT YRHAPNTGTR KSWAAGDATS RAVRLALMAK 240
  241 TGEMGYPSAL TAKTWGFYDV SFKGETFRFQ RPYGSYVMEN VLFKISFPAE FHSQTAVEAA 300
  301 MTLYEQMQAA GKTAADIEKV TIRTHEACLR IIDKKGPLNN PADRDHCIQY MVAVPLLFGR 360
  361 LTAADYEDEV AQDKRIDALR EKIVCYEDPA FTADYHDPEK RAIGNAITVE FTDGSRFGEV 420
  421 VVEYPIGHAR RRADGIPKLI EKFKINLARQ FPTRQQQRIL DVSLDRARLE QMPVNEYLDL 480
  481 YII

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	167.0
Match:	1szqA
Description:	Crystal Structure of 2-methylcitrate dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.534516847146079	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: