YRC Public Data Repository - Protein Structure Prediction

Protein:	LEUC_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	474 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEUC_SHEON.

Description	E-value	Query Range	Subject Range
gi\|7707823, gi\|1... - gi\|7707823\|dbj\|BAA95425.1\| 3-isopropylmalate dehydratase [Buchnera aphidicola str. APS (Acyrthosipho...	656.0	[0..11]	[474..7]
LEUC_BUCAI, LEU2... - 3-isopropylmalate dehydratase large subunit OS=Buchnera aphidicola subsp. Acyrthosiphon pisum GN=leu... LEUC_BUCAI - 3-isopropylmalate dehydratase large subunit OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strai...	656.0	[0..11]	[474..3]
LEU2_SYMTH, LEUC... - 3-isopropylmalate dehydratase large subunit OS=Symbiobacterium thermophilum GN=leuC PE=3 SV=1, 3-iso... LEUC_SYMTH - 3-isopropylmalate dehydratase large subunit OS=Symbiobacterium thermophilum (strain T / IAM 14863) G...	650.0	[0..8]	[472..8]
gi\|5912538 - gi\|5912538\|emb\|CAB56192.1\| isopropylmalate dehydratase subunit [Buchnera aphidicola]	647.0	[0..11]	[474..3]
LEUC_SHESA - 3-isopropylmalate dehydratase large subunit OS=Shewanella sp. (strain ANA-3) GN=leuC PE=3 SV=1	641.0	[0..1]	[474..1]
LEUC_SHESM - 3-isopropylmalate dehydratase large subunit OS=Shewanella sp. (strain MR-4) GN=leuC PE=3 SV=1	641.0	[0..1]	[474..1]
gi\|238718477, gi... - gi\|77962080\|ref\|ZP_00825905.1\| COG0065: 3-isopropylmalate dehydratase large subunit [Yersinia mollar...	640.0	[0..3]	[471..1]
LEUC_RHIME, LEU2... - 3-isopropylmalate dehydratase large subunit OS=Rhizobium meliloti GN=leuC PE=3 SV=1, 3-isopropylmala... LEUC_RHIME - 3-isopropylmalate dehydratase large subunit OS=Rhizobium meliloti (strain 1021) GN=leuC PE=3 SV=1	640.0	[0..9]	[472..3]
gi\|21960621, gi\|... - gi\|22127521\|ref\|NP_670944.1\| isopropylmalate isomerase large subunit [Yersinia pestis KIM], gi\|21960... gi\|45438252, gi\|... - gi\|45443383\|ref\|NP_994922.1\| isopropylmalate isomerase large subunit [Yersinia pestis biovar Microtu...	640.0	[0..11]	[472..32]
LEUC_RHIEC - 3-isopropylmalate dehydratase large subunit OS=Rhizobium etli (strain CFN 42 / ATCC 51251) GN=leuC P...	637.0	[0..9]	[472..3]

Back

Predicted Domain #1

Region A:
Residues: [1-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVPSKTIAP KTLYQKVWDA HIVATPEGEA PIIYVDRHLV HEVTSPQAFS GLKVAGRQLR  60
   61 APEKTFATMD HNTSTRSASL DALSPMARIQ VETLAQNCKD FGVLLYDIHH PNQGIVHVMG 120
  121 PELGITLPGT VIVCGDSHTA THGAFGALAF GIGTSEVEHV LATQTLRQLK AKTMKIEVRG 180
  181 QVTDGVTAKD IVLAIIGKIG MDGGTGYVVE FCGEAIEALS MEGRMTVCNM AIEMGAKAGM 240
  241 VAPDQTTFDY LEGREFAPKG EDWAQAVAEW KTLKTDVGAE FDATVVLDAA DIAPQLTWGT 300
  301 NPGQVVAIDA PVPNPADEVN PTIRSSMEKA LDYIGLTAGT PMTEVAINKV FIGSCTNSRI 360
  361 EDLRSAAKHA KGRKVAAGVT AIVVPGSGQV KAQAEAEGLD KIFIEAGFEW RLPGCSMCLA 420
  421 MNDDRLEAGD RCASTSNRNF EGRQGRGSRT HLVSPAMAAA AAIAGHFVDI RKPY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	143.0
Match:	2b3xA
Description:	Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-isopropylmalate dehydratase activity	11.6597692115322	bayes_pls_golite062009
catalytic activity	2.4040324437254	bayes_pls_golite062009
carbon-oxygen lyase activity	2.08349115784849	bayes_pls_golite062009
hydro-lyase activity	2.04845291489052	bayes_pls_golite062009
lyase activity	2.0080619912194	bayes_pls_golite062009
structural constituent of ribosome	0.952569345633996	bayes_pls_golite062009
aconitate hydratase activity	0.681826117995502	bayes_pls_golite062009
nucleic acid binding	0.0023376634609541	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: