YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24350016, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24350016, gi|....

Description	E-value	Query Range	Subject Range
gi\|115252480, gi... - gi\|126701043\|ref\|YP_001089940.1\| porphyrin biosynthesis protein [Clostridium difficile 630], gi\|1152...	274.0	[0..11]	[272..4]
gi\|145952571, gi... - gi\|90572857\|ref\|ZP_01229379.1\| hypothetical protein CdifQ_02003764 [Clostridium difficile QCD-32g58]...	272.0	[0..11]	[272..4]
gi\|196158491, gi... - gi\|88794338\|ref\|ZP_01110047.1\| uroporphyrin-III C-methyltransferase [Alteromonas macleodii 'Deep eco...	271.0	[0..3]	[254..226]
gi\|29895119, gi\|... - gi\|30019575\|ref\|NP_831206.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 14579], gi\|2... gi\|229043267, gi... - gi\|229043267\|ref\|ZP_04190989.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus AH676], gi... gi\|229144126, gi... - gi\|229144126\|ref\|ZP_04272541.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus BDRD-ST24]... gi\|229126841, gi... - gi\|229126841\|ref\|ZP_04255853.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus BDRD-Cer4]... gi\|228674452, gi... - gi\|229108983\|ref\|ZP_04238584.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus Rock1-15],...	267.0	[0..11]	[264..1]
gi\|89894970, gi\|... - gi\|89894970\|ref\|YP_518457.1\| hypothetical protein DSY2224 [Desulfitobacterium hafniense Y51], gi\|893...	267.0	[0..12]	[276..3]
gi\|77996628, gi\|... - gi\|78044513\|ref\|YP_361204.1\| uroporphyrinogen III synthase/methyltransferase [Carboxydothermus hydro...	267.0	[0..11]	[276..1]
gi\|109645297, gi... - gi\|68208394\|ref\|ZP_00560513.1\| Uroporphyrin-III C-methyltransferase, C-terminal [Desulfitobacterium ...	266.0	[0..12]	[276..3]
gi\|30248547, gi\|... - gi\|30248547\|ref\|NP_840617.1\| cysG_2; uroporphyrinogen-III methylase [Nitrosomonas europaea ATCC 1971...	265.0	[0..12]	[254..243]
gi\|75760415, gi\|... - gi\|75760415\|ref\|ZP_00740458.1\| Uroporphyrin-III C-methyltransferase [Bacillus thuringiensis serovar ...	265.0	[0..11]	[255..1]
CYSG_ACIAD - Siroheme synthase OS=Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) GN=cysG PE=3 SV=1	264.0	[0..1]	[253..204]

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Predicted Domain #1

Region A:
Residues: [1-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEILSLPGQS AKGKVWLVGA GPGDVELLTL KAWRILKSAD AVLYDALVSQ DILDLIPKDA  60
   61 EKIAVGKRAG KHSAAQDDIN QLLVTKAYTR KNVVRLKGGD PFIFGRGGEE LQTLVDAGVE 120
  121 FEVVPGITAA SGTAAYTGIP LTHRDYAQGV TFITGHCQLE SRPMDWQGYA NPNNTLVVYM 180
  181 GILNAGVIRA GLINAGRSPQ TPVAIVSKAT TQSQQRFIGQ LDSLEQLAAD PKLQMPALMI 240
  241 IGEVVGLSET LNWFQPKAEG SQSLEALNAP KVAVKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.39794
Match:	1pjqA
Description:	Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uroporphyrin-III C-methyltransferase activity	3.573271502205	bayes_pls_golite062009
C-methyltransferase activity	3.35393353163232	bayes_pls_golite062009
precorrin-4 C11-methyltransferase activity	2.18371138649366	bayes_pls_golite062009
catalytic activity	1.48349578618275	bayes_pls_golite062009
transferase activity	0.912524944496351	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.431791521097299	bayes_pls_golite062009
methyltransferase activity	0.424918406685891	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.28351517300952	bayes_pls_golite062009
uroporphyrinogen-III synthase activity	0.00871858903098705	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: