YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24347234, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	440 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24347234, gi|....

Description	E-value	Query Range	Subject Range
gi\|113971101, gi... - gi\|82496079\|ref\|ZP_00881650.1\| Isocitrate lyase [Shewanella sp. MR-4], gi\|82405883\|gb\|EAP46552.1\| Is... gi\|78506963, gi\|... - gi\|78685315\|ref\|ZP_00850094.1\| Isocitrate lyase [Shewanella sp. ANA-3], gi\|78506963\|gb\|EAP20477.1\| I...	588.0	[0..1]	[440..1]
gi\|114048335, gi... - gi\|114048335\|ref\|YP_738885.1\| isocitrate lyase [Shewanella sp. MR-7], gi\|113889777\|gb\|ABI43828.1\| is...	585.0	[0..1]	[440..1]
gi\|126637503, gi... - gi\|78366479\|ref\|ZP_00836759.1\| Isocitrate lyase [Shewanella sp. PV-4], gi\|78361524\|gb\|EAP03348.1\| Is...	584.0	[0..1]	[440..10]
gi\|124545071, gi... - gi\|124545071\|ref\|ZP_01704298.1\| isocitrate lyase [Shewanella putrefaciens 200], gi\|124511258\|gb\|EAY5... gi\|82719405, gi\|... - gi\|82743243\|ref\|ZP_00905901.1\| Isocitrate lyase [Shewanella sp. W3-18-1], gi\|82719405\|gb\|EAP54313.1\|...	583.0	[0..1]	[440..1]
gi\|69163859, gi\|... - gi\|69952910\|ref\|ZP_00640238.1\| Isocitrate lyase [Shewanella frigidimarina NCIMB 400], gi\|69163859\|gb...	583.0	[0..3]	[440..1]
gi\|146292342, gi... - gi\|77814247\|ref\|ZP_00813510.1\| Isocitrate lyase [Shewanella putrefaciens CN-32], gi\|77810749\|gb\|EAO9...	583.0	[0..1]	[440..1]
gi\|56477970, gi\|... - gi\|56477970\|ref\|YP_159559.1\| isocitrate lyase [Aromatoleum aromaticum EbN1], gi\|56314013\|emb\|CAI0865...	582.0	[0..8]	[440..4]
gi\|69157443, gi\|... - gi\|91792604\|ref\|YP_562255.1\| isocitrate lyase [Shewanella denitrificans OS217], gi\|91714606\|gb\|ABE54...	581.0	[0..1]	[440..1]
gi\|68516287, gi\|... - gi\|68545927\|ref\|ZP_00585476.1\| Isocitrate lyase [Shewanella amazonensis SB2B], gi\|68516287\|gb\|EAN399...	581.0	[0..8]	[440..6]
gi\|26111215, gi\|... - gi\|26250784\|ref\|NP_756824.1\| isocitrate lyase [Escherichia coli CFT073], gi\|26111215\|gb\|AAN83398.1\|A...	580.0	[0..6]	[440..6]

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Predicted Domain #1

Region A:
Residues: [1-440]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKATQTSRQ AQIDAIKKDW AENPRWKNVR RPYTAEEVVA LRGSIVPENT IAKRGAAKLW  60
   61 DLVNGGSKKG YVNSLGALTG GQAVQQAKAG IEAIYLSGWQ VAADANLAGT MYPDQSLYPA 120
  121 NSVPAVVSRI NNSFRRADQI QWSNGVNPED ENFVDYFLPI IADAEAGFGG VLNAFELMKS 180
  181 MIDAGAAGVH FEDQLASVKK CGHMGGKVLV PTQEAVQKLV AARLAADVSG VETLVIARTD 240
  241 ANAADLLTSD CDPYDRDFVT GERTNEGFYR VNAGLDQAIS RGLAYAPYAD LIWCETAKPD 300
  301 LEEARRFAEA IHAQYPDQLL AYNCSPSFNW KKNLDDATIA RFQQALSDMG YKYQFITLAG 360
  361 IHNMWYNMFD LAYDYARGEG MKHYVEKVQE VEFAAAKKGY TFVAHQQEVG TGYFDQVTTV 420
  421 IQGGHSSVTA LTGSTEEEQF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	166.0
Match:	1igwA
Description:	Isocitrate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.59838799615646	bayes_pls_golite062009
methylisocitrate lyase activity	2.06824730122158	bayes_pls_golite062009
3-methyl-2-oxobutanoate hydroxymethyltransferase activity	0.987472653142222	bayes_pls_golite062009
isocitrate lyase activity	0.714624467380094	bayes_pls_golite062009
transferase activity	0.368032846714701	bayes_pls_golite062009
lyase activity	0.0456521871650777	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: