YRC Public Data Repository - Protein Structure Prediction

Protein:	PRPB_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	292 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRPB_SHEON.

Description	E-value	Query Range	Subject Range
gi\|46915335, gi\|... - gi\|54301915\|ref\|YP_131908.1\| 2-methylisocitrate lyase [Photobacterium profundum SS9], gi\|46915335\|em...	335.0	[0..4]	[290..2]
gi\|90409987, gi\|... - gi\|90409987\|ref\|ZP_01218004.1\| putative carboxyphosphonoenolpyruvate phosphonomutase [Photobacterium...	333.0	[0..4]	[290..2]
gi\|94500804, gi\|... - gi\|94500804\|ref\|ZP_01307333.1\| PEP phosphonomutase and related enzyme [Oceanobacter sp. RED65], gi\|9...	325.0	[0..1]	[292..1]
gi\|76792554, gi\|... - gi\|76792554\|ref\|ZP_00775052.1\| carboxyphosphonoenolpyruvate phosphonomutase [Pseudoalteromonas atlan...	323.0	[0..4]	[292..2]
gi\|114770708, gi... - gi\|114770708\|ref\|ZP_01448198.1\| putative methylisocitrate lyase [alpha proteobacterium HTCC2255], gi... gi\|114770708 - gi\|114770708\|ref\|ZP_01448198.1\| putative methylisocitrate lyase [alpha proteobacterium HTCC2255] gi\|221133519 - gi\|221133519\|ref\|ZP_03559824.1\| 2-methylisocitrate lyase [Glaciecola sp. HTCC2999]	322.0	[0..4]	[292..2]
gi\|120554586, gi... - gi\|77953313\|ref\|ZP_00817722.1\| Isocitrate lyase and phosphorylmutase [Marinobacter aquaeolei VT8], g...	320.0	[0..1]	[292..1]
gi\|94418099, gi\|... - gi\|94418099\|ref\|ZP_01297915.1\| hypothetical protein PaerP_01000249 [Pseudomonas aeruginosa PA7], gi\|... gi\|107100258 - gi\|107100258\|ref\|ZP_01364176.1\| hypothetical protein PaerPA_01001282 [Pseudomonas aeruginosa PACS2] gi\|218893260, gi... - gi\|218893260\|ref\|YP_002442129.1\| 2-methylisocitrate lyase [Pseudomonas aeruginosa LESB58], gi\|218773... gi\|11347535 - pir\|\|A83545 carboxyphosphonoenolpyruvate phosphonomutase PA0796 [imported] - Pseudomonas aeruginosa ... gi\|115583935, gi... - gi\|53727343\|ref\|ZP_00138395.2\| COG2513: PEP phosphonomutase and related enzymes [Pseudomonas aerugin... gi\|84322746, gi\|... - gi\|84322746\|ref\|ZP_00970829.1\| COG2513: PEP phosphonomutase and related enzymes [Pseudomonas aerugin... gi\|9946688, gi\|1... - gi\|9946688\|gb\|AAG04185.1\|AE004515_1 carboxyphosphonoenolpyruvate phosphonomutase [Pseudomonas aerugi...	320.0	[0..4]	[292..7]
gi\|70729244, gi\|... - gi\|70729244\|ref\|YP_258980.1\| 2-methylisocitrate lyase [Pseudomonas fluorescens Pf-5], gi\|68343543\|gb...	320.0	[0..2]	[292..5]
gi\|126171085, gi... - gi\|84316708\|ref\|ZP_00965177.1\| COG2513: PEP phosphonomutase and related enzymes [Pseudomonas aerugin...	319.0	[0..4]	[292..7]
gi\|91715022, gi\|... - gi\|91793020\|ref\|YP_562671.1\| 2-methylisocitrate lyase [Shewanella denitrificans OS217], gi\|91715022\|...	319.0	[0..4]	[292..2]

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Predicted Domain #1

Region A:
Residues: [1-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQSAGLRFR QALANSKPLQ IVGTTNAYFA LMAEQTGFQA LYLSGAGVAN ASYGLPDLGM  60
   61 TSMNDVLIDA GRITSATQLP LLVDIDTGWG GAFNIARTIK EFEKIGVAAV HMEDQVSQKR 120
  121 CGHRPNKAVV STEEMVDRIK AAVDARTDPN FVIMARTDAV AVEGLEAGIE RAKAYIAAGA 180
  181 DMIFAEALTE LDQYRHFKAQ VKAPILANMT EFGQTQLFNK EELAQAGADM VLYPLGTFRA 240
  241 ANQAALKVMQ ALMNDGHQRN VLDTMQTRAD LYKYLGYHAF EDKLDQLFSQ DK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.0
Match:	1mumA
Description:	2-methylisocitrate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.96882793316847	bayes_pls_golite062009
methylisocitrate lyase activity	2.09739770469711	bayes_pls_golite062009
citrate (pro-3S)-lyase activity	0.86095690814621	bayes_pls_golite062009
lyase activity	0.70986506551964	bayes_pls_golite062009
transferase activity	0.5687068385416	bayes_pls_golite062009
oxo-acid-lyase activity	0.404868472347919	bayes_pls_golite062009
carbon-carbon lyase activity	0.36217387205482	bayes_pls_golite062009
carboxyvinyl-carboxyphosphonate phosphorylmutase activity	0.2132734143313	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: