YRC Public Data Repository - Protein Structure Prediction

Protein:	YN60_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YN60_YEAST.

Description	E-value	Query Range	Subject Range
YNL320W - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... YN60_YEAST - Uncharacterized membrane protein YNL320W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...	2.0E-52	[1..284]	[1..284]
bem46 - esterase /lipase BEM46_SCHPO - Protein bem46 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=bem46 PE=2 SV=3	2.0E-48	[2..280]	[9..291]
gi\|27311639, gi\|... - gi\|6091713\|gb\|AAF03425.1\|AC010797_1 unknown protein [Arabidopsis thaliana], gi\|6016726\|gb\|AAF01552.1...	3.0E-48	[14..278]	[1..258]
gi\|987287 - gi\|987287\|gb\|AAB53686.1\| temperature sensitive supressor of Saccharomyces cerevisiae bem1/bud5	2.0E-47	[2..280]	[48..330]
FAM108A1 - family with sequence similarity 108, member A1 ENSPTRT00000018753 - null	1.0E-45	[4..281]	[21..304]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLWKVSKMFL GGLVALTTIS VATLYHYQNR LVYPSWAQGA RNHVDTPDSR GIPYEKLTLI  60
   61 TQDHIKLEAW DIKNENSTST VLILCPNAGN IGYFILIIDI FYRQFGMSVF IYSYRGYGNS 120
  121 EGSPSEKGLK LDADCVISHL STDSFHSKRK LVLYGRSLGG ANALYIASKF RDLCDGVILE 180
  181 NTFLSIRKVI PYIFPLLKRF TLLCHEIWNS EGLMGSCSSE TPFLFLSGLK DEIVPPFHMR 240
  241 KLYETCPSSN KKIFEFPLGS HNDTIIQDGY WDIIRDFLIE KGFI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.522879
Match:	1qfsA_
Description:	Prolyl oligopeptidase, N-terminal domain; Prolyl oligopeptidase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	0.685577841077355	bayes_pls_golite062009
catalytic activity	0.629869101256762	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: