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View Structure Prediction Details

Protein: REF2_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 533 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for REF2_YEAST.

Description E-value Query
Range
Subject
Range
REF2_YEAST - RNA end formation protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REF2 PE=1 SV...
gi|190404850 - gi|190404850|gb|EDV08117.1| RNA-binding protein [Saccharomyces cerevisiae RM11-1a]
REF2 - RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation,...
0.0 [1..533] [1..533]
gi|6694636 - gi|6694636|gb|AAF25330.1|AF203752_1 Brca1 [Hipposideros commersoni]
0.007 [184..365] [612..813]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.009 [128..373] [542..772]

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Predicted Domain #1
Region A:
Residues: [1-465]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAPVPQLVN ISHALQASTI QQIRLDMVDF NKDCKLSSIQ LARIDKYIDS LQAALNQFTK  60
   61 DNLHIERKEK NVTEADIQLY SGLKSMYLDY LNQLIKLKHE KQHHSTPPIA NDVSLDFFVN 120
  121 QLPKFSPEER KNYIDNLILN KNSHNRLSKM DGLVDAVINL CVLDTSVAEN VRSYMKLLDT 180
  181 LGFQKGSNST GTKANLKKKL ASSKAKIKDS EKEKEKEKDK SKVKMKTKLK PSPLLNNDDK 240
  241 NSSPSPTAST SSMKKLKSGL FNKNEAKSTE SLPTSSKKKL SFSKYLNKDD ADMTKLGTKR 300
  301 SIDVDFKVNP EASTVASNII SSSTSGSSTT TVATPASSEE PLKKKTKISV QDSNVQSILR 360
  361 NGKPKKARIS SIKFLDDSQL IKVYGDDLPN QGLQVSPTQL KKILKPFKEG EPKEIILFED 420
  421 MSIKLKPLDL MFLKNTNSDD YMDISETKGG PIHCETRTPL IYRKN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.0
Match: 1iwpA
Description: Diol dehydratase, alpha subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [466-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNHFNPDLNK RPPREPIEFD LNGNTNSTPT IAKAFGKNSL LLRKDRGGLP YKHVPIVKRN  60
   61 KYPPRPVH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [335-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASSEEPLKK KTKISVQDSN VQSILRNGKP KKARISSIKF LDDSQLIKVY GDDLPNQGLQ  60
   61 VSPTQLKKIL KPFKEGEPKE IILFEDMSIK LKPLDLMFLK NTNSDDYMDI SETKGGPIHC 120
  121 ETRTPLIYRK NFNHFNPDLN KRPPREPIEF DLNGNTNSTP TIAKAFGKNS LLLRKDRGGL 180
  181 PYKHVPIVKR NKYPPRPVH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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