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View Structure Prediction Details

Protein: TOA1_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 286 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOA1_YEAST.

Description E-value Query
Range
Subject
Range
gi|8778565, gi|2... - gi|8778565|gb|AAF79573.1|AC022464_31 F22G5.18 [Arabidopsis thaliana], pir||D86209 protein F22G5.18 [...
3.0E-91 [2..279] [3..390]
gi|151945287 - gi|151945287|gb|EDN63530.1| transcription factor IIA subunit alpha [Saccharomyces cerevisiae YJM789]
TOA1_YEAST - Transcription initiation factor IIA large subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
TOA1 - TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator...
gi|207341051 - gi|207341051|gb|EDZ69216.1| YOR194Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407510 - gi|190407510|gb|EDV10777.1| transcription initiation factor IIA large chain [Saccharomyces cerevisia...
2.0E-82 [1..286] [1..286]
TOA1_SCHPO - Transcription initiation factor IIA large subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
SPBC28F2.09 - transcription factor TFIIA complex large subunit
2.0E-78 [1..286] [1..369]
gi|12313737, gi|... - gi|12963759|ref|NP_076119.1| general transcription factor IIA, 1-like [Mus musculus], gi|12313737|gb...
1.0E-46 [146..285] [315..468]
gi|123996161, gi... - gi|123996161|gb|ABM85682.1| TFIIA-alpha/beta-like factor [synthetic construct], gi|123981326|gb|ABM8...
gi|19684124, gi|... - gi|26787968|ref|NP_006863.2| general transcription factor IIA, 1-like isoform 1 [Homo sapiens], gi|1...
1.0E-44 [140..285] [319..478]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNAEASRVY EIIVESVVNE VREDFENAGI DEQTLQDLKN IWQKKLTETK VTTFSWDNQF  60
   61 NEGNINGVQN DLNFNLATPG VNSSEFNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 181.38764
Match: 1ytfB_
Description: Large chain TOA1, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [89-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEENTGNEGL ILPNINSNNN IPHSGETNIN TNTVEATNNS GATLNTNTSG NTNADVTSQP  60
   61 KIEVKPEIEL TINNANITTV ENIDDESEKK DDEEKEEDVE KTRKEKEQIE QVKLQAKKEK 120
  121 R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [210-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SALLDTDEVG SELDDSDDDY LISEGEEDGP DENLMLCLYD KVTRTKARWK CSLKDGVVTI  60
   61 NRNDYTFQKA QVEAEWV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 370.68867
Match: 1ytfC_
Description: Large chain TOA1, C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle