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View Structure Prediction Details

Protein: PTN2B_ARATH
Organism: Arabidopsis thaliana
Length: 632 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTN2B_ARATH.

Description E-value Query
Range
Subject
Range
gi|6522932, gi|1... - gi|6522932|emb|CAB62119.1| putative tyrosine phosphatase [Arabidopsis thaliana], pir||T45864 probabl...
427.0 [0..1] [632..1]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METDPANSSS KSPAVVSEKD VLIPEPSENT VGVVQDPVSA EREAHEDSIS TEASVAKVDD  60
   61 TQMPASSTGS EPLSKTDDIV PCPPGSSPRE SPPSIFSSSG LSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WAKSFKFQQQ DPNRTDSGMS AFTRFTSELG LHLPTKGSEE VGDSRSSNTQ VGGAFESLTK  60
   61 AVVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.09691
Match: 1jlnA
Description: Tyrosine phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [168-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSRGAVKAMQ VKARHIVSQN KRRYQEGEFD LDMTYITENI IAMGFPAGDI SSGLFGFFEG  60
   61 LYRNHMEEVI KFFETHHKDK YKVYNLCSER LYDASRFEGK VASFPFDDHN CPPIQLIPSF 120
  121 CQSAYTWLKE DIQNVVVVHC KAGMARTGLM ICCLLLYLKF FPTAEEAIDY YNQKRCLDGK 180
  181 ALVLPSQIRY VKYYERVQNQ FDGKVPPERR CMLRGFRLIN CPYWIRPAIT ISNHTDILFS 240
  241 TKKHQKTKDL GPEDFWIKAP KKGVVVFAIP GEAGLTELAG DFKIHFQDSD GDFYCWLNTT 300
  301 LTDNRTMLKG SDFDGFDKRK LPAPGFHVEI VMIEPDNSQP TKSKSDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.30103
Match: 1d5rA
Description: Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.532771614927042 bayes_pls_golite062009
hydrolase activity 0.40946506358565 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.38379754974017 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.379743522718551 bayes_pls_golite062009
phosphatase activity 0.37915439306018 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.0905316221038603 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [515-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQQQSQSSSS ADSSKLKSNE KDDDVFSDSD GEEEGNSQSY STNEKTASSM HTTSKPHQIN  60
   61 EPPKRDDPSA NRSVTSSSSS GHYNPIPNNS LAVSDIKAIA ADASVFSFGD EEEDYESD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle