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View Structure Prediction Details

Protein: PYRDA_STRP1
Organism: Streptococcus pyogenes serotype M1
Length: 311 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRDA_STRP1.

Description E-value Query
Range
Subject
Range
gi|55739111 - gb|AAV62752.1| dihydroorotate dehydrogenase A [Streptococcus thermophilus CNRZ1066]
gi|55739111, gi|... - gi|55823126|ref|YP_141567.1| dihydroorotate dehydrogenase 1A [Streptococcus thermophilus CNRZ1066], ...
238.0 [0..1] [311..16]

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Predicted Domain #1
Region A:
Residues: [1-311]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSTATQIGH FSFDNCLMNA AGVYCMTKEE LMEVEKSQAA SFVTKTGTLE VRPGNPEPRY  60
   61 ADTRLGSINS MGLPNNGFRY YLDFVSDLAK TGQHKPHFLS VVGLSPTETE TILKAIMASD 120
  121 YEGLVELNLS CPNVPGKPQI AYDFETTDQL LENIFTYYTK PLGIKLPPYF DIVHFDQAAA 180
  181 IFNKYPLSFV NCVNSIGNGL VIKDEQVLIK PKNGFGGIGG DYIKPTALAN VHAFYKRLKP 240
  241 SIHIIGTGGV KTGRDAFEHI LCGASMVQIG TALHQEGPAI FERVTKELKT IMVEKGYQSL 300
  301 DDFRGNLRYK D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.221849
Match: 1dorA
Description: Dihydroorotate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dihydroorotate dehydrogenase activity 2.73800716363956 bayes_pls_golite062009
dihydroorotate oxidase activity 2.35584458985229 bayes_pls_golite062009
catalytic activity 1.94749091175302 bayes_pls_golite062009
dihydropyrimidine dehydrogenase (NADP+) activity 1.76080169529176 bayes_pls_golite062009
oxidoreductase activity 1.34004057547793 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 0.708198550325532 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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