YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: twk-12
Organism: Caenorhabditis elegans
Length: 713 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for twk-12.

Description E-value Query
Range
Subject
Range
gi|119595686, gi... - gi|2826773|emb|CAA75348.1| voltage gated potassium channel [Homo sapiens], gi|119595687|gb|EAW75281....
264.0 [0..82] [696..73]

Back

Predicted Domain #1
Region A:
Residues: [1-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLFKKIQWF CNLIRLRSYY KFLLLIAYTA FGAWLFRTYE LQADIKRRSV FGNTTNLVRR  60
   61 QLAERWIEMH KDAVLRNDSA LRFRRAAEAV EWLLDELNLS DHIRDLSEET PWTWTGAMFY 120
  121 AGQLYTTIGY GYPTTKTDEG RICTIFYALF GIPCFLMYLK IENAIEWKKD KQLGKRALKM 180
  181 HGLINDSFQS IGKTLSKKMK KYYKKLRRSR VGRILLPTRV TAMKDGFEDP EAAEERKKKP 240
  241 FPIPIAIIML IIWICFSASM FCIWEDTWVF SSAVYFFIVS ISTVGLGDML FRTPDMMVFN 300
  301 FLLILVGLAL LSMCFELITD RVAKWKQKRF DEHIKKVQKM AFQVFEKDPF IEEAPPLGIR 360
  361 MAPNLMQIAA THVSEEKRGF FAEFKDWFAG KVTDNVIQSK LEDSDDESDS EEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [414-454]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEEFDSPQIA TVTANDLIVC SNGAATRRVS KQSYALSDIS N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 1xl4A
Description: Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [455-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSNSKILPGN NYGQLLDRIK AMEKFKPKKN DLDSRMFAKF LENKKLAKIL EQTELRELAT  60
   61 VSCQTDLSGL VVQRRNPKGR HARIGSCSSQ STMSTLLPNK MH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [557-713]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APDEDSVMSF TFGDLKFDYK TEPFIDEYYI RESNHSIFDF DEDETVRIPQ KMLISRPGMP  60
   61 PPPPSRPLNL ASPLRTLLEK EQKYDEDPEI QLTPRRLNSL SDIQARKVKL GVDENLQHAR 120
  121 LVCGLLPQDF DSPSTSTSTS MIDSGYELSK RDASTMA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle