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View Structure Prediction Details

Protein: mre-11
Organism: Caenorhabditis elegans
Length: 728 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mre-11.

Description E-value Query
Range
Subject
Range
gi|187031641, gi... - gi|39593405|emb|CAE64875.1| Hypothetical protein CBG09687 [Caenorhabditis briggsae], gi|187031641|em...
gi|157763180 - gi|157763180|ref|XP_001673932.1| Hypothetical protein CBG09687 [Caenorhabditis briggsae AF16]
521.0 [0..1] [728..1]

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Predicted Domain #1
Region A:
Residues: [1-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGSDDSFDD FVPDSQEPAS SRTRNQDHLD DDEVPCSQRP DAANDTMVED LDEGDEPAHD  60
   61 ESEDIIKILV ATDIHCGYGE NKANIHMDAV NTFEEVLQIA TEQKVDMILL GGDLFHENNP 120
  121 SREVQHRVTQ LLRQYCLNGN PIALEFLSDA SVNFNQSVFG HVNYYDQNLN VGLPIFTIHG 180
  181 NHDDLSGKGL TALDLLHESG LVNLFGKHSN IQEFIVSPIL LRKGETRLAL YGIGSQRDDR 240
  241 LVRAFKNNSI SFLRPNAGAE DWFNLFVLHQ NRPRRAMHRS TGNFLPESLI PQFFDLLIWG 300
  301 HEHECKPDPQ YVASSEAVGD GFYILQPGST VATSLTPEEA LQKNAFLIKI KGRKFASKPI 360
  361 PLQTVRPMVC DELLLDKIPP GSRPILKTDR PKHTDGRYID EIAIEAKINE MITTAKAKRR 420
  421 PRQPELPLIR LKVIYDGDWL NITPANAKRI GLRYEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 1ii7A
Description: Mre11
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 1.43500260769599 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.24384090418481 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.243831086941 bayes_pls_golite062009
phosphatase activity 1.22221319991731 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.685850975270683 bayes_pls_golite062009
hydrolase activity 0.135444325609812 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [457-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVANAVDMVF IKKNNKPKEG KLQTENEKNI TEMADEMGQV SATNLQTIIN DYFINQPLVD  60
   61 QMTVLKPIGI GRALEQYSA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [536-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEEGGLATSA NRNFDSCLMH QIDVVRKTLK KMPLPPINDP SDLDKFRDLI TKDLYDMKKA  60
   61 DSERFKNPVA DVEMEEDEDD PQYYMPPQST SRTNYASGSE DEVANSDEEM GSSISRHSKQ 120
  121 PTTRGRGRGA RGAGASRETT RGRSNKVVST RQIDSDGFEI INDSPSPPPA SRSTRGKARG 180
  181 KSAPSKKRDL SFF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle