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View Structure Prediction Details

Protein: gi|190406177
Organism: Saccharomyces cerevisiae RM11-1a
Length: 918 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190406177.

Description E-value Query
Range
Subject
Range
PEP3_YEAST - Vacuolar membrane protein PEP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEP3 PE=1...
gi|190406177 - gi|190406177|gb|EDV09444.1| vacuolar membrane protein [Saccharomyces cerevisiae RM11-1a]
gi|207343032 - gi|207343032|gb|EDZ70617.1| YLR148Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151941310 - gi|151941310|gb|EDN59688.1| carboxypeptidase Y-deficient [Saccharomyces cerevisiae YJM789]
PEP3 - Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular ...
0.0 [1..918] [1..918]
gi|12641617 - gi|12641617|emb|CAC27452.1| DigA protein [Emericella nidulans]
gi|40744683, gi|... - gi|67523621|ref|XP_659870.1| hypothetical protein AN2266.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
0.0 [4..916] [24..961]
gi|7959211 - gi|7959211|dbj|BAA95999.1| KIAA1475 protein [Homo sapiens]
0.0 [20..916] [70..985]
gi|15221363 - gi|15221363|ref|NP_172709.1| Pep3/Vps18/deep orange family protein [Arabidopsis thaliana]
0.0 [20..913] [24..971]
dor-PA - The gene deep orange is referred to in FlyBase by the symbol Dmel\dor (CG3093, FBgn0000482). It is a...
0.0 [4..913] [45..997]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..913] [45..997]

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Predicted Domain #1
Region A:
Residues: [1-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKTRIEEVQ LQFLTGNTEL THLKVSNDQL IVTTQRTIYR INLQDPAIVN HFDCPLSKEL  60
   61 ETIMNVHVSP MGSVILIRTN FGRYMLLKDG EFTQLNKIKN LDLSSLHWIN ETTFLMGIKK 120
  121 TPKLYRVELT GKDITTKLWY ENKKLSGGID GIAYWEGSLL LTIKDNILYW RDVTNMKFPL 180
  181 VLPDESEQFE RLKHHAIKKF DSYNGLFAWV TSNGIVFGDL KEKQMEKDPA SNNFGKFLSS 240
  241 SKVLLNFELP DYQNDKDHLI KDIVLTAFHI LLLRKNTVTM VSQLNNDVVF HETIPRHQLT 300
  301 GSNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [305-823]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSNEKFLGLV RDSVKETFWC FSNINVFEII IENEPNSVWN LLVRDNKFDK ALSLKGLTVR  60
   61 EIESVKLSKA MYLFHTAKDF HSAAQTLGSM KDLSHFGEIA LNFLQIKDYN DLNVILIKQL 120
  121 DNVPWKSTQV VLSSWIIWNF MKQLNDIELK INTTKPASTD EDNLLNWNLN LKEKSNELTK 180
  181 FLESHLEKLD NETVYQIMSK QNRQNELLIF ASLINDMKFL LSFWIDQGNW YESLKILLTI 240
  241 NNHDLVYKYS LILLLNSPEA TVSTWMKIKD LDPNKLIPTI LKFFTNWQNN SKLITNISEY 300
  301 PENYSLTYLK WCVREVPKMC NPIVYNSILY MMITDPRNDM ILENDIIKFM KSNENKYDLN 360
  361 FQLRLSLKFK KTKTSIFLLT RLNLFEDAID LALKNNLIDD CKVIVNDEIL IEDYKLRKRL 420
  421 WLKIAKHLLL SMKDIDIKQL IRTILNDSNE ILTIKDLLPF FNEYTTIANL KEELIKFLEN 480
  481 HNMKMNEISE DIINSKNLKV EINTEISKFN EIYRILEPG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 1b89A_
Description: Clathrin heavy chain proximal leg segment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [824-918]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSCDECGKFL QIKKFIVFPC GHCFHWNCII RVILNSNDYN LRQKTENFLK AKSKHNLNDL  60
   61 ENIIVEKCGL CSDININKID QPISIDETEL AKWNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.437 a.65.1 Annexin
View Download 0.547 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.342 a.4.3 ARID-like
View Download 0.382 a.118.14 FliG
View Download 0.373 d.34.1 DNA-binding domain of Mlu1-box binding protein MBP1
View Download 0.332 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.329 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.295 a.46.1 Methionine synthase domain
View Download 0.295 a.4.1 Homeodomain-like
View Download 0.277 b.34.8 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
View Download 0.266 a.3.1 Cytochrome c
View Download 0.263 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.255 d.198.1 Type III secretory system chaperone
View Download 0.251 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.249 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.247 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.244 a.3.1 Cytochrome c
View Download 0.242 a.118.8 TPR-like
View Download 0.232 a.77.1 DEATH domain
View Download 0.227 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.227 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.218 a.2.7 tRNA-binding arm
View Download 0.213 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.210 a.77.1 DEATH domain
View Download 0.208 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.207 a.3.1 Cytochrome c

Predicted Domain #4
Region A:
Residues: [816-918]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYRILEPGKS CDECGKFLQI KKFIVFPCGH CFHWNCIIRV ILNSNDYNLR QKTENFLKAK  60
   61 SKHNLNDLEN IIVEKCGLCS DININKIDQP ISIDETELAK WNE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.57
Match: 2ecnA
Description: No description for 2ecnA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle