Bait Protein: | MLP2 |
Organism: | Saccharomyces cerevisiae |
Publication: | Keck JM, Jones MH, Wong CC, Binkley J, Chen D, Jaspersen SL, Holinger EP, Xu T, Niepel M, Rout MP, Vogel J, Sidow A, Yates JR, Winey M., A Cell Cycle Phosphoproteome of the Yeast Centrosome, Science 24 June 2011: 1557-1561. |
Comments: | #11 Mitotic Prep1-TiO2 enriched, new search criteria |
Raw Data: |
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FILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
YIL002W-A | Putative protein of unknown function; identified by expression profiling and mass spectrometry | 28 | 35 | 94.2% | 0.135 | 7729 |
[ |
CDC31 | Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication i... | 15 | 16 | 82.6% | 0.0265 | 18751 |
[ |
SPC42 | Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate att... | 65 | 76 | 81.3% | 0.0558 | 42271 |
[ |
MLP2 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 290 | 378 | 78.0% | 0.06 | 195140 |
[ |
SPC110 | Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nu... | 153 | 194 | 74.9% | 0.0548 | 111782 |
[ |
CMD1 | Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, act... | 12 | 14 | 74.1% | 0.0254 | 16135 |
[ |
SPC72 | Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them... | 32 | 34 | 69.8% | 0.0146 | 72105 |
[ |
CNM67 | Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclea... | 61 | 75 | 68.0% | 0.0344 | 67400 |
[ |
SPC29 | Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inn... | 19 | 34 | 61.3% | 0.0358 | 29280 |
[ |
TUB4 | Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of th... | 14 | 15 | 47.4% | 0.00845 | 52628 |
[ |
BFA1 | Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pa... | 23 | 24 | 44.9% | 0.0111 | 66087 |
[ |
RPP2B | Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... | 4 | 4 | 44.5% | 0.00969 | 11050 |
[ |
NUD1 | Component of the spindle pole body outer plaque, required for exit from mitosis | 52 | 57 | 43.6% | 0.0179 | 94104 |
[ |
NBP1 | Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuc... | 14 | 14 | 40.8% | 0.0117 | 37354 |
[ |
BBP1 | Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periph... | 12 | 12 | 39.5% | 0.00831 | 45384 |
[ |
YLR146W-A | Putative protein of unknown function | 4 | 4 | 35.5% | 0.0172 | 7078 |
[ |
RPP2A | Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction... | 3 | 4 | 34.9% | 0.0101 | 10746 |
[ |
ECM34 | Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomeri... | 2 | 2 | 25.9% | 0.00314 | 19812 |
[ |
STM1 | Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with r... | 3 | 3 | 23.4% | 0.00293 | 29995 |
[ |
MPS2 | Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required f... | 5 | 6 | 22.0% | 0.00413 | 44585 |
[ |
MRPS9 | Mitochondrial ribosomal protein of the small subunit | 2 | 2 | 20.9% | 0.00192 | 31925 |
[ |
KAR1 | Essential protein involved in karyogamy during mating and in spindle pole body duplication during mi... | 8 | 8 | 20.8% | 0.00493 | 50653 |
[ |
PDC1 | Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates... | 4 | 4 | 18.7% | 0.00189 | 61495 |
[ |
UTP11 | Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA a... | 2 | 2 | 16.4% | 0.00213 | 29735 |
[ |
ENO1 | Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosph... | 4 | 4 | 15.8% | 0.00244 | 46816 |
[ |
ENO2 | Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosp... | 4 | 4 | 15.8% | 0.00244 | 46914 |
[ |
SPC98 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 6 | 7 | 14.4% | 0.00221 | 98227 |
[ |
PMA1 | Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... | 9 | 10 | 13.6% | 0.0029 | 99619 |
[ |
AAC3 | Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synth... | 2 | 2 | 13.0% | 0.00174 | 33313 |
[ |
ASK10 | Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a... | 9 | 9 | 12.6% | 0.00209 | 126864 |
[ |
YTM1 | Constituent of 66S pre-ribosomal particles, forms a complex with Nop7p and Erb1p that is required fo... | 2 | 2 | 12.6% | 0.00116 | 51359 |
[ |
RPP0 | Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... | 2 | 3 | 12.5% | 0.00256 | 33717 |
[ |
CDC19 | Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvat... | 4 | 4 | 12.0% | 0.00213 | 54545 |
[ |
YOR019W | Protein of unknown function that may interact with ribosomes, based on co-purification experiments | 3 | 3 | 11.6% | 0.0011 | 83366 |
[ |
HSC82 | Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, a... | 4 | 4 | 11.5% | 0.00151 | 80900 |
[ |
TCP1 | Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; inv... | 4 | 4 | 11.3% | 0.00191 | 60481 |
[ |
CDC5 | Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and ... | 5 | 5 | 10.8% | 0.00189 | 81031 |
[ |
SUP35 | Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a domi... | 4 | 4 | 10.8% | 0.00156 | 76551 |
[ |
CDC14 | Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR ... | 3 | 3 | 10.5% | 0.00145 | 61907 |
[ |
SFG1 | Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (whic... | 2 | 2 | 10.4% | 0.00154 | 39021 |
[ |
MET17 | Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for s... | 2 | 2 | 10.1% | 0.0012 | 48672 |
[ |
NSR1 | Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ri... | 3 | 3 | 9.9% | 0.00193 | 44535 |
[ |
TEF1, TEF2 | Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... | 3 | 3 | 9.8% | 0.00175 | 50033 |
[ |
BUB2 | Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spi... | 2 | 2 | 9.8% | 0.00174 | 35028 |
[ |
SPC97 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 6 | 7 | 9.4% | 0.00227 | 96825 |
[ |
MYO3 | One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect o... | 5 | 5 | 8.9% | 0.00105 | 142507 |
[ |
NOP58 | Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the ... | 2 | 2 | 8.8% | 0.00104 | 56956 |
[ |
PPQ1 | Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational su... | 2 | 2 | 8.7% | 9.71E-4 | 61421 |
[ |
NUP60 | Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process control... | 2 | 2 | 8.7% | 9.89E-4 | 59039 |
[ |
SFI1 | Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the ... | 7 | 7 | 8.4% | 0.00197 | 112978 |
[ |
NSP1 | Essential component of the nuclear pore complex, which mediates nuclear import and export, found in ... | 3 | 3 | 8.3% | 9.72E-4 | 86516 |
[ |
YKR023W | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... | 2 | 2 | 8.3% | 0.00101 | 60799 |
[ |
EDC3 | Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically ... | 2 | 2 | 8.2% | 9.68E-4 | 61340 |
[ |
POM152 | Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore... | 5 | 5 | 7.6% | 9.97E-4 | 151652 |
[ |
BZZ1 | SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polym... | 2 | 2 | 7.6% | 8.42E-4 | 71171 |
[ |
SIR2 | Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespa... | 2 | 2 | 7.5% | 9.49E-4 | 63262 |
[ |
SPB1 | AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation;... | 3 | 3 | 7.4% | 9.51E-4 | 96485 |
[ |
RAD27 | 5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation ... | 2 | 2 | 7.3% | 0.0014 | 43279 |
[ |
YAP6 | Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithi... | 2 | 2 | 6.8% | 0.00139 | 43597 |
[ |
BFR1 | Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segre... | 2 | 2 | 6.4% | 0.00113 | 54639 |
[ |
TRK1 | Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter... | 3 | 3 | 6.3% | 6.48E-4 | 141073 |
[ |
APN1 | Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by o... | 2 | 2 | 6.3% | 0.00145 | 41439 |
[ |
MPP10 | Component of the SSU processome and 90S preribosome, required for pre-18S rRNA processing, interacts... | 2 | 2 | 6.2% | 8.99E-4 | 66953 |
[ |
HAL5 | Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disrupt... | 2 | 2 | 6.1% | 6.24E-4 | 95455 |
[ |
MLP1 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 8 | 10 | 5.8% | 0.00142 | 218454 |
[ |
PAP2 | Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP co... | 2 | 2 | 5.8% | 9.13E-4 | 66031 |
[ |
KAR2 | ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... | 2 | 2 | 5.7% | 7.82E-4 | 74468 |
[ |
FLO5 | Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the s... | 2 | 2 | 5.6% | 4.96E-4 | 111981 |
[ |
HMG2 | One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in... | 3 | 3 | 5.5% | 7.65E-4 | 115692 |
[ |
DED1 | ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all ye... | 2 | 2 | 5.5% | 8.83E-4 | 65553 |
[ |
APL4 | Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; invo... | 2 | 2 | 5.4% | 6.41E-4 | 93624 |
[ |
KGD1 | Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step... | 2 | 2 | 5.3% | 5.26E-4 | 114416 |
[ |
MAK5 | Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA vir... | 2 | 2 | 5.3% | 6.9E-4 | 87048 |
[ |
ECM32 | DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is... | 2 | 2 | 5.2% | 4.76E-4 | 126970 |
[ |
PIP2 | Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)... | 2 | 2 | 5.2% | 5.35E-4 | 114710 |
[ |
CDC15 | Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anap... | 2 | 2 | 5.1% | 5.47E-4 | 110285 |
[ |
RMD8 | Cytosolic protein required for sporulation | 2 | 2 | 5.0% | 8.05E-4 | 75914 |
[ |
FUN30 | Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Sn... | 2 | 2 | 4.9% | 4.71E-4 | 128507 |
[ |
TIF4631 | Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that al... | 2 | 2 | 4.9% | 5.6E-4 | 107101 |
[ |
BCK2 | Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which ... | 2 | 2 | 4.9% | 6.27E-4 | 93738 |
[ |
UBP7 | Ubiquitin-specific protease that cleaves ubiquitin-protein fusions | 3 | 3 | 4.8% | 7.47E-4 | 123134 |
[ |
PTR3 | Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses exte... | 2 | 2 | 4.7% | 7.86E-4 | 76286 |
[ |
IQG1 | Essential protein required for determination of budding pattern, promotes localization of axial mark... | 3 | 3 | 4.6% | 5.35E-4 | 172830 |
[ |
ISW2 | ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, f... | 2 | 2 | 4.6% | 4.76E-4 | 130327 |
[ |
TYW1 | Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adja... | 2 | 2 | 4.6% | 6.58E-4 | 89805 |
[ |
BOI2 | Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence ... | 2 | 2 | 4.5% | 5.13E-4 | 115688 |
[ |
HSL7 | Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization ... | 2 | 4 | 4.5% | 0.00129 | 95153 |
[ |
MSS116 | DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar ... | 2 | 2 | 4.4% | 8.03E-4 | 76269 |
[ |
STE13 | Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repe... | 2 | 2 | 4.1% | 5.73E-4 | 107200 |
[ |
COS111 | Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtel... | 2 | 2 | 4.1% | 5.77E-4 | 104505 |
[ |
MLH1 | Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis;... | 2 | 2 | 4.0% | 6.93E-4 | 87062 |
[ |
DNF1 | Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contribute... | 3 | 3 | 3.9% | 5.09E-4 | 177797 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 2 | 2 | 3.9% | 6.33E-4 | 93289 |
[ |
BAS1 | Myb-related transcription factor involved in regulating basal and induced expression of genes of the... | 2 | 2 | 3.9% | 6.57E-4 | 89604 |
[ |
ENA1 | P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance | 2 | 2 | 3.8% | 4.89E-4 | 120357 |
[ |
CWC22 | Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putat... | 2 | 2 | 3.8% | 9.24E-4 | 67294 |
[ |
SNT2 | DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a ... | 3 | 3 | 3.7% | 5.7E-4 | 163203 |
[ |
VAS1 | Mitochondrial and cytoplasmic valyl-tRNA synthetase | 2 | 2 | 3.7% | 4.83E-4 | 125770 |
[ |
AI1 | Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intro... | 2 | 2 | 3.7% | 6.39E-4 | 96079 |
[ |
GAT1 | Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-typ... | 2 | 2 | 3.7% | 0.00105 | 56328 |
[ |
MCM7 | Component of the hexameric MCM complex, which is important for priming origins of DNA replication in... | 2 | 2 | 3.6% | 6.31E-4 | 94875 |
[ |
GCR1 | Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and fu... | 2 | 2 | 3.6% | 6.79E-4 | 87729 |
[ |
STU1 | Component of the mitotic spindle that binds to interpolar microtubules via its association with beta... | 2 | 2 | 3.5% | 3.52E-4 | 174176 |
[ |
DEF1 | RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and prot... | 2 | 2 | 3.5% | 7.23E-4 | 83973 |
[ |
DRS1 | Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S r... | 2 | 2 | 3.3% | 7.09E-4 | 84843 |
[ |
TPS2 | Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the... | 2 | 2 | 3.2% | 5.95E-4 | 102976 |
[ |
MSC6 | Protein of unknown function; mutant is defective in directing meiotic recombination events to homolo... | 2 | 2 | 3.2% | 7.71E-4 | 79947 |
[ |
MLH2 | Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic ... | 2 | 2 | 3.2% | 7.67E-4 | 78248 |
[ |
PDR12 | Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter re... | 3 | 3 | 3.1% | 5.29E-4 | 171064 |
[ |
ACS2 | Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histo... | 2 | 2 | 3.1% | 7.81E-4 | 75492 |
[ |
SLF1 | RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA trans... | 2 | 2 | 3.1% | 0.00119 | 50943 |
[ |
RPO41 | Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; re... | 2 | 2 | 3.0% | 3.95E-4 | 153047 |
[ |
DOP1 | Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, ... | 2 | 2 | 2.8% | 3.14E-4 | 194686 |
[ |
SMC1 | Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation an... | 3 | 3 | 2.8% | 6.53E-4 | 141280 |
[ |
KIN1 | Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic f... | 2 | 2 | 2.8% | 5.01E-4 | 120071 |
[ |
RIF1 | Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telom... | 3 | 3 | 2.7% | 4.17E-4 | 217959 |
[ |
KEM1 | Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved i... | 2 | 2 | 2.7% | 3.49E-4 | 175459 |
[ |
ATG26 | UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside m... | 2 | 2 | 2.7% | 4.45E-4 | 136054 |
[ |
YEF3 | Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes b... | 2 | 2 | 2.7% | 5.11E-4 | 115945 |
[ |
HEF3 | Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates ... | 2 | 2 | 2.7% | 5.11E-4 | 115869 |
[ |
INP53 | Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in t... | 2 | 2 | 2.6% | 4.82E-4 | 124577 |
[ |
JSN1 | Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated ... | 2 | 2 | 2.6% | 4.89E-4 | 120374 |
[ |
SKG3 | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell pe... | 2 | 2 | 2.6% | 5.2E-4 | 114111 |
[ |
FUN12 | GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes a... | 2 | 2 | 2.6% | 5.32E-4 | 112268 |
[ |
MOT1 | Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA vi... | 2 | 2 | 2.5% | 2.86E-4 | 209975 |
[ |
MEC1 | Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for... | 3 | 3 | 2.4% | 3.38E-4 | 273340 |
[ |
HFA1 | Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondria... | 2 | 2 | 2.4% | 2.51E-4 | 241784 |
[ |
KIN2 | Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic f... | 2 | 2 | 2.4% | 4.65E-4 | 128338 |
[ |
NEW1 | ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the s... | 2 | 2 | 2.3% | 4.46E-4 | 134331 |
[ |
FAB1 | 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylino... | 3 | 3 | 2.2% | 3.51E-4 | 257447 |
[ |
HAP1 | Zinc finger transcription factor involved in the complex regulation of gene expression in response t... | 2 | 2 | 2.2% | 3.55E-4 | 166107 |
[ |
OSH3 | Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members ha... | 2 | 2 | 2.2% | 5.35E-4 | 113760 |
[ |
NUM1 | Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may med... | 3 | 3 | 2.1% | 2.91E-4 | 313032 |
[ |
FKS1 | Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... | 2 | 2 | 2.1% | 2.84E-4 | 214849 |
[ |
DNF2 | Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contribute... | 2 | 2 | 1.9% | 3.31E-4 | 182617 |
[ |
KOG1 | Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or To... | 2 | 2 | 1.9% | 3.42E-4 | 177608 |
[ |
HSL1 | Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates wit... | 2 | 2 | 1.9% | 3.51E-4 | 169592 |
[ |
SNQ2 | Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug ... | 2 | 2 | 1.9% | 3.55E-4 | 168766 |
[ |
THO2 | Subunit of the THO complex, which is required for efficient transcription elongation and involved in... | 2 | 2 | 1.8% | 3.34E-4 | 183930 |
[ |
GEA2 | Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transp... | 2 | 2 | 1.8% | 3.65E-4 | 165667 |
[ |
FAS1 | Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty a... | 2 | 2 | 1.7% | 2.6E-4 | 228689 |
[ |
REV3 | Catalytic subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication ... | 2 | 2 | 1.7% | 3.55E-4 | 172956 |
[ |
BOI1 | Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence ... | 2 | 2 | 1.7% | 5.44E-4 | 109295 |
[ |
GLT1 | NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglut... | 2 | 2 | 1.4% | 2.49E-4 | 238100 |
[ |
RAD50 | Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in ve... | 2 | 2 | 1.4% | 4.06E-4 | 152568 |
[ |
BNI1 | Formin, nucleates the formation of linear actin filaments, involved in cell processes such as buddin... | 2 | 2 | 1.3% | 2.73E-4 | 219701 |
[ |
PDR18 | Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resist... | 2 | 2 | 1.1% | 4.0E-4 | 149750 |
[ |
POL2 | Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhi... | 2 | 2 | 0.8% | 2.4E-4 | 255669 |
[ |
DYN1 | Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation;... | 2 | 2 | 0.7% | 1.3E-4 | 471351 |