Bait Protein: | MLP2 |
Organism: | Saccharomyces cerevisiae |
Publication: | Keck JM, Jones MH, Wong CC, Binkley J, Chen D, Jaspersen SL, Holinger EP, Xu T, Niepel M, Rout MP, Vogel J, Sidow A, Yates JR, Winey M., A Cell Cycle Phosphoproteome of the Yeast Centrosome, Science 24 June 2011: 1557-1561. |
Comments: | #12 Mitotic Prep1-TiO2 Flowthrough |
Raw Data: |
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FILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
YIL002W-A | Putative protein of unknown function; identified by expression profiling and mass spectrometry | 35 | 46 | 94.2% | 0.0791 | 7729 |
[ |
CDC31 | Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication i... | 20 | 25 | 85.1% | 0.0184 | 18751 |
[ |
MLP2 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 308 | 406 | 79.3% | 0.0287 | 195140 |
[ |
SPC42 | Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate att... | 44 | 48 | 75.2% | 0.0157 | 42271 |
[ |
SPC110 | Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nu... | 167 | 204 | 74.4% | 0.0256 | 111782 |
[ |
CMD1 | Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, act... | 15 | 18 | 74.1% | 0.0145 | 16135 |
[ |
RPP2B | Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... | 2 | 2 | 66.4% | 0.00216 | 11050 |
[ |
CNM67 | Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclea... | 56 | 70 | 63.2% | 0.0143 | 67400 |
[ |
SPC72 | Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them... | 27 | 31 | 62.4% | 0.00591 | 72105 |
[ |
TUB4 | Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of th... | 17 | 21 | 51.2% | 0.00527 | 52628 |
[ |
ANS1 | Putative protein of unknown function; transcription dependent upon Azf1p | 3 | 3 | 47.2% | 0.00224 | 16635 |
[ |
RPC19 | RNA polymerase subunit AC19, common to RNA polymerases I and III | 2 | 2 | 44.4% | 0.00167 | 16151 |
[ |
NDL1 | Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein target... | 2 | 2 | 43.9% | 0.00126 | 21530 |
[ |
SPC29 | Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inn... | 10 | 11 | 41.1% | 0.00516 | 29280 |
[ |
BFA1 | Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pa... | 15 | 16 | 37.8% | 0.00331 | 66087 |
[ |
RPP2A | Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction... | 4 | 4 | 36.8% | 0.00448 | 10746 |
[ |
YLR146W-A | Putative protein of unknown function | 4 | 4 | 35.5% | 0.00765 | 7078 |
[ |
NUD1 | Component of the spindle pole body outer plaque, required for exit from mitosis | 25 | 27 | 34.9% | 0.00376 | 94104 |
[ |
SNC2 | Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory v... | 2 | 2 | 33.0% | 0.00206 | 12957 |
[ |
NBP1 | Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuc... | 10 | 11 | 29.2% | 0.00409 | 37354 |
[ |
TAF4 | TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p sub... | 4 | 4 | 29.1% | 0.00122 | 42336 |
[ |
PDX3 | Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcr... | 2 | 2 | 27.2% | 0.00104 | 26908 |
[ |
CKA2 | Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and ... | 2 | 2 | 26.5% | 7.0E-4 | 39404 |
[ |
RIB3 | 3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase), required for riboflavin biosynthesis ... | 2 | 2 | 26.4% | 0.00114 | 22568 |
[ |
SNO2 | Protein of unknown function, nearly identical to Sno3p; expression is induced before the diauxic shi... | 2 | 2 | 25.7% | 0.00107 | 25208 |
[ |
SNO3 | Protein of unknown function, nearly identical to Sno2p; expression is induced before the diauxic shi... | 2 | 2 | 25.7% | 0.00107 | 25132 |
[ |
COX18 | Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p... | 3 | 3 | 25.6% | 0.00113 | 35650 |
[ |
YOR062C | Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1... | 2 | 2 | 25.4% | 8.85E-4 | 31880 |
[ |
MPS2 | Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required f... | 5 | 7 | 23.8% | 0.00215 | 44585 |
[ |
STM1 | Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with r... | 3 | 3 | 23.4% | 0.0013 | 29995 |
[ |
TCP1 | Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; inv... | 6 | 6 | 22.9% | 0.00127 | 60481 |
[ |
THI13 | Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a s... | 2 | 2 | 22.9% | 6.98E-4 | 38574 |
[ |
TAM41 | Mitochondrial protein involved in protein import into the mitochondrial matrix; maintains the functi... | 2 | 2 | 22.3% | 6.16E-4 | 44200 |
[ |
NOP1 | Nucleolar protein, component of the small subunit processome complex, which is required for processi... | 2 | 2 | 22.3% | 7.26E-4 | 34465 |
[ |
CTP1 | Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family | 2 | 2 | 21.7% | 7.94E-4 | 32173 |
[ |
FCF2 | Essential nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p... | 2 | 2 | 21.7% | 0.00109 | 25636 |
[ |
HOR2 | One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol b... | 2 | 2 | 21.6% | 9.49E-4 | 27814 |
[ |
MNP1 | Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with si... | 3 | 3 | 21.6% | 0.00183 | 20650 |
[ |
EAF5 | Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex | 2 | 2 | 21.5% | 8.5E-4 | 31644 |
[ |
RHO4 | Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in t... | 2 | 2 | 21.3% | 8.15E-4 | 32186 |
[ |
INM2 | Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesiu... | 3 | 3 | 21.2% | 0.00122 | 32093 |
[ |
RSM27 | Mitochondrial ribosomal protein of the small subunit | 2 | 2 | 20.9% | 0.00216 | 12393 |
[ |
BBP1 | Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periph... | 7 | 7 | 20.5% | 0.00216 | 45384 |
[ |
LCL3 | Putative protein of unknown function, has homology to Staphylococcus aureus nuclease; green fluoresc... | 2 | 2 | 20.4% | 8.66E-4 | 32112 |
[ |
TIM22 | Essential core component of the mitochondrial TIM22 complex involved in insertion of polytopic prote... | 2 | 2 | 20.3% | 0.00115 | 21864 |
[ |
PMA1 | Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... | 12 | 14 | 19.9% | 0.00181 | 99619 |
[ |
YNG2 | Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has simila... | 3 | 3 | 19.9% | 0.00126 | 32086 |
[ |
PRE9 | Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit; may be replaced by the alp... | 2 | 2 | 19.8% | 9.2E-4 | 28714 |
[ |
BUD21 | Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated... | 2 | 2 | 19.6% | 0.00111 | 24385 |
[ |
UTP11 | Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA a... | 3 | 3 | 19.2% | 0.00142 | 29735 |
[ |
RRP15 | Nucleolar protein, constituent of pre-60S ribosomal particles; required for proper processing of the... | 2 | 2 | 19.2% | 9.49E-4 | 28212 |
[ |
SNX4 | Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Gol... | 2 | 2 | 19.1% | 5.61E-4 | 49002 |
[ |
BUD27 | Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by TOR ki... | 5 | 5 | 18.8% | 7.45E-4 | 91422 |
[ |
PDC1 | Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates... | 4 | 4 | 18.7% | 8.43E-4 | 61495 |
[ |
YTM1 | Constituent of 66S pre-ribosomal particles, forms a complex with Nop7p and Erb1p that is required fo... | 3 | 3 | 18.7% | 7.74E-4 | 51359 |
[ |
TRR2 | Mitochondrial thioredoxin reductase involved in protection against oxidative stress, required with G... | 2 | 2 | 18.7% | 6.94E-4 | 37087 |
[ |
HSL7 | Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization ... | 9 | 11 | 18.6% | 0.00158 | 95153 |
[ |
RMD6 | Protein required for sporulation | 2 | 2 | 18.6% | 0.00103 | 26815 |
[ |
MRH4 | Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochon... | 3 | 3 | 18.5% | 6.34E-4 | 63058 |
[ |
CPR1 | Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization... | 2 | 2 | 18.5% | 0.00146 | 17391 |
[ |
YML131W | Putative protein of unknown function with similarity to medium chain dehydrogenase/reductases; expre... | 3 | 4 | 18.4% | 0.0013 | 39976 |
[ |
TFB3 | Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initia... | 3 | 3 | 18.4% | 0.00111 | 38128 |
[ |
ATC1 | Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishm... | 2 | 2 | 18.4% | 8.07E-4 | 33114 |
[ |
AIM20 | Putative protein of unknown function; overexpression causes a cell cycle delay or arrest; green fluo... | 2 | 2 | 18.1% | 0.00116 | 22840 |
[ |
AIM45 | Protein with similarity to mammalian electron transfer flavoprotein complex subunit ETF-alpha; inter... | 2 | 2 | 18.0% | 6.9E-4 | 36803 |
[ |
TEM1 | GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin a... | 2 | 2 | 18.0% | 9.68E-4 | 27296 |
[ |
AAC3 | Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synth... | 2 | 2 | 17.6% | 7.73E-4 | 33313 |
[ |
YIA6 | Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YE... | 2 | 2 | 17.2% | 6.36E-4 | 41954 |
[ |
YKL151C | Putative protein of unknown function; YKL151C promoter contains STREs (stress response elements) and... | 3 | 3 | 17.2% | 0.00106 | 37357 |
[ |
GLN4 | Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminyla... | 4 | 4 | 16.9% | 5.87E-4 | 93133 |
[ |
PDB1 | E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved mu... | 2 | 2 | 16.7% | 6.48E-4 | 40054 |
[ |
FBA1 | Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversio... | 2 | 2 | 16.7% | 6.61E-4 | 39621 |
[ |
ELP4 | Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; requ... | 4 | 4 | 16.4% | 0.00104 | 51156 |
[ |
PDS1 | Securin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, ess... | 2 | 2 | 16.4% | 6.36E-4 | 41838 |
[ |
SPS4 | Protein whose expression is induced during sporulation; not required for sporulation; heterologous e... | 2 | 2 | 16.3% | 7.02E-4 | 38591 |
[ |
YOL162W | Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family | 2 | 2 | 16.3% | 0.0011 | 24483 |
[ |
SPR6 | Protein of unknown function, expressed during sporulation; not required for sporulation, but gene ex... | 2 | 2 | 16.2% | 0.00124 | 21512 |
[ |
YPL264C | Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an e... | 3 | 3 | 16.1% | 0.00101 | 39703 |
[ |
KRS1 | Lysyl-tRNA synthetase | 3 | 3 | 15.9% | 6.02E-4 | 67959 |
[ |
MNI1 | Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion ... | 2 | 2 | 15.9% | 6.29E-4 | 42515 |
[ |
ECM34 | Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomeri... | 2 | 2 | 15.9% | 0.0014 | 19812 |
[ |
SPC97 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 8 | 9 | 15.8% | 0.0013 | 96825 |
[ |
KAR1 | Essential protein involved in karyogamy during mating and in spindle pole body duplication during mi... | 5 | 5 | 15.7% | 0.00137 | 50653 |
[ |
RSC2 | Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-s... | 5 | 5 | 15.5% | 6.67E-4 | 102300 |
[ |
SPC98 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 9 | 11 | 15.4% | 0.00154 | 98227 |
[ |
AVT6 | Vacuolar aspartate and glutamate exporter; member of a family of seven genes (AVT1-7) related to ves... | 2 | 2 | 15.4% | 5.3E-4 | 48840 |
[ |
ATG17 | Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an aut... | 2 | 2 | 15.3% | 5.69E-4 | 48656 |
[ |
ABC1 | Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genet... | 2 | 2 | 15.2% | 4.74E-4 | 56742 |
[ |
SPB1 | AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation;... | 5 | 5 | 15.1% | 7.05E-4 | 96485 |
[ |
HPC2 | Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene tra... | 3 | 3 | 15.1% | 5.71E-4 | 67517 |
[ |
ARH1 | Oxidoreductase of the mitochondrial inner membrane, involved in cytoplasmic and mitochondrial iron h... | 2 | 2 | 15.0% | 4.81E-4 | 56237 |
[ |
IRC7 | Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mu... | 2 | 2 | 15.0% | 6.98E-4 | 36971 |
[ |
BUB2 | Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spi... | 2 | 2 | 15.0% | 7.75E-4 | 35028 |
[ |
HST4 | Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in sil... | 2 | 2 | 14.9% | 6.41E-4 | 41765 |
[ |
RTN1 | ER membrane protein that interacts with Sey1p to maintain ER morphology; interacts with exocyst subu... | 2 | 2 | 14.9% | 8.04E-4 | 32916 |
[ |
YGL082W | Putative protein of unknown function; predicted prenylation/proteolysis target of Afc1p and Rce1p; g... | 2 | 2 | 14.7% | 6.23E-4 | 43321 |
[ |
SGF29 | Probable subunit of SAGA histone acetyltransferase complex | 2 | 2 | 14.7% | 9.16E-4 | 29381 |
[ |
BDF1 | Protein involved in transcription initiation at TATA-containing promoters; associates with the basal... | 4 | 4 | 14.6% | 6.92E-4 | 76978 |
[ |
HEM14 | Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosy... | 2 | 2 | 14.5% | 4.4E-4 | 59703 |
[ |
CLB2 | B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2... | 2 | 2 | 14.5% | 4.83E-4 | 56247 |
[ |
SWA2 | Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoatin... | 4 | 4 | 14.4% | 7.1E-4 | 75020 |
[ |
AIM10 | Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria... | 2 | 2 | 14.4% | 4.12E-4 | 65880 |
[ |
PEX29 | Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and di... | 2 | 2 | 14.4% | 4.28E-4 | 63543 |
[ |
TIF3 | Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif ... | 2 | 2 | 14.4% | 5.44E-4 | 48522 |
[ |
PHO4 | Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p... | 2 | 2 | 14.4% | 7.6E-4 | 34089 |
[ |
RPP0 | Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... | 3 | 4 | 14.4% | 0.00152 | 33717 |
[ |
RCR2 | Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affect... | 3 | 4 | 14.3% | 0.00226 | 24211 |
[ |
SRP101 | Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-... | 6 | 6 | 14.2% | 0.00115 | 69278 |
[ |
PET8 | S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial ca... | 2 | 2 | 14.1% | 8.35E-4 | 31027 |
[ |
SPT23 | ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ... | 4 | 4 | 14.0% | 4.39E-4 | 121338 |
[ |
NBA1 | Protein of unknown function, localizes to the bud neck and cytoplasm; interacts with Nap1p; may inte... | 2 | 2 | 14.0% | 4.74E-4 | 55923 |
[ |
PEX25 | Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenan... | 3 | 3 | 14.0% | 9.03E-4 | 44911 |
[ |
MRP51 | Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutat... | 2 | 2 | 14.0% | 6.9E-4 | 39445 |
[ |
ECM18 | Protein of unknown function, similar to Rlp24p | 4 | 4 | 13.9% | 0.00105 | 53185 |
[ |
MUM2 | Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, whi... | 3 | 3 | 13.9% | 9.72E-4 | 41433 |
[ |
YAT1 | Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transpor... | 4 | 4 | 13.8% | 6.91E-4 | 77766 |
[ |
BIO3 | 7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynt... | 3 | 3 | 13.8% | 7.41E-4 | 53709 |
[ |
DSD1 | D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a re... | 2 | 2 | 13.8% | 5.54E-4 | 47828 |
[ |
AIM23 | Putative protein of unknown function; the authentic non-tagged protein is detected in highly purifie... | 3 | 3 | 13.8% | 0.001 | 41461 |
[ |
ATP3 | Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily ... | 2 | 2 | 13.8% | 7.63E-4 | 34351 |
[ |
MGM101 | Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, requi... | 2 | 2 | 13.8% | 8.82E-4 | 30090 |
[ |
SDS24 | One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implic... | 2 | 2 | 13.7% | 4.5E-4 | 57187 |
[ |
SFG1 | Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (whic... | 2 | 2 | 13.6% | 6.86E-4 | 39021 |
[ |
PPQ1 | Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational su... | 3 | 3 | 13.5% | 6.48E-4 | 61421 |
[ |
SUA5 | Single-stranded telomeric DNA-binding protein, required for normal telomere length; null mutant lack... | 2 | 2 | 13.4% | 5.57E-4 | 46539 |
[ |
IST1 | Protein with a positive role in the multivesicular body sorting pathway; functions and forms a compl... | 2 | 2 | 13.4% | 7.96E-4 | 34496 |
[ |
RIM8 | Protein involved in proteolytic activation of Rim101p in response to alkaline pH; interacts with ESC... | 2 | 2 | 13.3% | 4.38E-4 | 60864 |
[ |
UGA2 | Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a ... | 2 | 2 | 13.3% | 4.77E-4 | 54189 |
[ |
VTC2 | Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... | 6 | 6 | 13.2% | 8.6E-4 | 95441 |
[ |
YLR345W | Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metaboli... | 3 | 3 | 13.2% | 6.99E-4 | 58386 |
[ |
MRF1 | Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the p... | 2 | 2 | 13.1% | 5.75E-4 | 46770 |
[ |
CTR1 | High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low... | 3 | 3 | 13.1% | 8.77E-4 | 44442 |
[ |
IBD2 | Component of the BUB2-dependent spindle checkpoint pathway, interacts with Bfa1p and functions upstr... | 2 | 2 | 13.1% | 6.76E-4 | 40016 |
[ |
MLP1 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 13 | 14 | 13.0% | 8.86E-4 | 218454 |
[ |
ENO2 | Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosp... | 2 | 2 | 13.0% | 5.43E-4 | 46914 |
[ |
ENO1 | Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosph... | 2 | 2 | 13.0% | 5.43E-4 | 46816 |
[ |
YFL042C | Putative protein of unknown function; YFL042C is not an essential gene | 4 | 4 | 12.9% | 7.04E-4 | 76347 |
[ |
AMN1 | Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stabilit... | 2 | 2 | 12.9% | 4.32E-4 | 62686 |
[ |
YDL038C | YDL038C SGDID:S000002196, Chr IV from 384078-382327, reverse complement, Uncharacterized ORF, "Putat... | 2 | 2 | 12.9% | 4.07E-4 | 58523 |
[ |
ARC35 | Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin pa... | 2 | 2 | 12.9% | 6.94E-4 | 39566 |
[ |
BOI1 | Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence ... | 4 | 4 | 12.8% | 4.84E-4 | 109295 |
[ |
FOL2 | GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway | 3 | 3 | 12.8% | 0.00146 | 27769 |
[ |
ABP140 | Nonessential protein that binds actin filaments and localizes to actin patches and cables, has simil... | 2 | 2 | 12.7% | 3.78E-4 | 71486 |
[ |
YOR338W | Putative protein of unknown function; YOR338W transcription is regulated by Azf1p and its transcript... | 2 | 2 | 12.7% | 6.54E-4 | 42109 |
[ |
YOR019W | Protein of unknown function that may interact with ribosomes, based on co-purification experiments | 3 | 3 | 12.6% | 4.88E-4 | 83366 |
[ |
NUP60 | Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process control... | 2 | 2 | 12.6% | 4.4E-4 | 59039 |
[ |
TRM82 | Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguan... | 2 | 2 | 12.6% | 5.34E-4 | 50488 |
[ |
ORC6 | Subunit of the origin recognition complex, which directs DNA replication by binding to replication o... | 2 | 2 | 12.6% | 5.45E-4 | 50296 |
[ |
TOP1 | Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the... | 5 | 5 | 12.5% | 7.71E-4 | 89995 |
[ |
HSC82 | Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, a... | 5 | 5 | 12.5% | 8.41E-4 | 80900 |
[ |
STP22 | Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into ... | 2 | 2 | 12.5% | 6.16E-4 | 43330 |
[ |
PDC6 | Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino ... | 3 | 3 | 12.4% | 6.32E-4 | 61581 |
[ |
MSO1 | Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows... | 2 | 2 | 12.4% | 0.00113 | 23351 |
[ |
DIA2 | Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays... | 4 | 4 | 12.3% | 6.36E-4 | 86801 |
[ |
FPS1 | Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glyce... | 3 | 3 | 12.3% | 5.32E-4 | 73877 |
[ |
SIF2 | WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middl... | 2 | 2 | 12.3% | 4.43E-4 | 59161 |
[ |
TRM13 | 2'-O-methyltransferase responsible for modification of tRNA at position 4; C-terminal domain has sim... | 2 | 2 | 12.2% | 4.98E-4 | 54095 |
[ |
MGR1 | Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondria... | 2 | 2 | 12.2% | 5.69E-4 | 47156 |
[ |
GSF2 | ER localized integral membrane protein that may promote secretion of certain hexose transporters, in... | 2 | 2 | 12.2% | 5.89E-4 | 45870 |
[ |
MRPS9 | Mitochondrial ribosomal protein of the small subunit | 2 | 2 | 12.2% | 8.53E-4 | 31925 |
[ |
VTC3 | Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... | 4 | 4 | 12.1% | 5.68E-4 | 96553 |
[ |
DEP1 | Transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and m... | 2 | 2 | 12.1% | 5.65E-4 | 48672 |
[ |
NPL3 | RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from n... | 2 | 2 | 12.1% | 5.73E-4 | 45407 |
[ |
CDC19 | Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvat... | 4 | 4 | 12.0% | 9.49E-4 | 54545 |
[ |
TFC3 | Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); ... | 7 | 7 | 11.9% | 7.16E-4 | 132108 |
[ |
HAL5 | Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disrupt... | 3 | 3 | 11.9% | 4.16E-4 | 95455 |
[ |
FRM2 | Protein of unknown function, involved in the integration of lipid signaling pathways with cellular h... | 2 | 2 | 11.9% | 0.00123 | 21232 |
[ |
BRN1 | Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA ge... | 3 | 3 | 11.8% | 4.72E-4 | 86230 |
[ |
DSN1 | Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins ... | 2 | 2 | 11.8% | 4.12E-4 | 65692 |
[ |
UBP6 | Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubi... | 2 | 2 | 11.8% | 4.75E-4 | 57111 |
[ |
CDC3 | Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recrui... | 2 | 2 | 11.7% | 4.56E-4 | 60039 |
[ |
DBP3 | Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis | 3 | 3 | 11.7% | 6.81E-4 | 58827 |
[ |
CHL1 | Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DN... | 4 | 4 | 11.6% | 5.51E-4 | 98806 |
[ |
NDE2 | Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2... | 2 | 2 | 11.6% | 4.35E-4 | 61659 |
[ |
GPA2 | Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gp... | 2 | 2 | 11.6% | 5.28E-4 | 50448 |
[ |
HXT11 | Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator s... | 2 | 2 | 11.5% | 4.18E-4 | 62733 |
[ |
GUA1 | GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-ph... | 3 | 3 | 11.4% | 6.78E-4 | 58482 |
[ |
ERG13 | 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-Co... | 2 | 2 | 11.4% | 4.83E-4 | 55014 |
[ |
YKL027W | Protein of unknown function, localized to the mitochondrial outer membrane | 2 | 2 | 11.4% | 5.31E-4 | 50266 |
[ |
RPN7 | Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae reg... | 2 | 2 | 11.4% | 5.53E-4 | 48959 |
[ |
YLR137W | Putative S-adenosylmethionine-dependent methyltransferase | 2 | 2 | 11.4% | 6.47E-4 | 41392 |
[ |
AGE2 | ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Netw... | 2 | 2 | 11.4% | 7.96E-4 | 32638 |
[ |
BAS1 | Myb-related transcription factor involved in regulating basal and induced expression of genes of the... | 3 | 3 | 11.3% | 4.39E-4 | 89604 |
[ |
CWC22 | Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putat... | 2 | 2 | 11.3% | 4.11E-4 | 67294 |
[ |
NOP12 | Nucleolar protein involved in pre-25S rRNA processing and biogenesis of large 60S ribosomal subunit;... | 3 | 3 | 11.3% | 7.75E-4 | 51942 |
[ |
PRE4 | Beta 7 subunit of the 20S proteasome | 2 | 2 | 11.3% | 8.92E-4 | 29443 |
[ |
YPR015C | Putative protein of unknown function; overexpression causes a cell cycle delay or arrest | 2 | 2 | 11.3% | 9.61E-4 | 27775 |
[ |
HSH49 | U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed... | 2 | 2 | 11.3% | 0.00111 | 24503 |
[ |
YRA2 | Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitut... | 2 | 2 | 11.3% | 0.00117 | 23778 |
[ |
MGS1 | Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; ... | 4 | 4 | 11.1% | 8.08E-4 | 66544 |
[ |
APD1 | Protein of unknown function, required for normal localization of actin patches and for normal tolera... | 2 | 2 | 11.1% | 7.51E-4 | 35759 |
[ |
CBP2 | Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to ... | 3 | 3 | 11.0% | 5.65E-4 | 73861 |
[ |
YDL025C | Putative protein kinase, potentially phosphorylated by Cdc28p; YDL025C is not an essential gene | 2 | 2 | 11.0% | 3.83E-4 | 69615 |
[ |
MAS1 | Smaller subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cle... | 2 | 2 | 11.0% | 5.14E-4 | 51084 |
[ |
POT1 | 3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA an... | 2 | 2 | 11.0% | 5.69E-4 | 44730 |
[ |
HIS2 | Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidin... | 2 | 2 | 11.0% | 7.08E-4 | 38582 |
[ |
NAB2 | Nuclear polyadenylated RNA-binding protein required for nuclear mRNA export and poly(A) tail length ... | 2 | 2 | 10.9% | 4.52E-4 | 58321 |
[ |
RMD1 | Cytoplasmic protein required for sporulation | 4 | 4 | 10.9% | 0.0011 | 49932 |
[ |
NOP13 | Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM) | 2 | 2 | 10.9% | 5.89E-4 | 45667 |
[ |
SOR2 | Protein of unknown function; protein sequence is 99% identical to the Sor1p sorbitol dehydrogenase; ... | 2 | 2 | 10.9% | 6.65E-4 | 38097 |
[ |
SOR1 | Sorbitol dehydrogenase; expression is induced in the presence of sorbitol or xylose | 2 | 2 | 10.9% | 6.65E-4 | 38166 |
[ |
GPM2 | Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in... | 2 | 2 | 10.9% | 7.63E-4 | 36073 |
[ |
SUP35 | Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a domi... | 4 | 5 | 10.8% | 8.66E-4 | 76551 |
[ |
UIP5 | Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific prote... | 2 | 2 | 10.8% | 5.36E-4 | 50981 |
[ |
ERJ5 | Type I membrane protein with a J domain is required to preserve the folding capacity of the endoplas... | 2 | 2 | 10.8% | 8.04E-4 | 34191 |
[ |
MOT2 | Subunit of the CCR4-NOT complex, which has roles in transcription regulation, mRNA degradation, and ... | 3 | 3 | 10.6% | 6.06E-4 | 65354 |
[ |
MCH5 | Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-depen... | 2 | 2 | 10.6% | 4.55E-4 | 57566 |
[ |
PHO80 | Cyclin, interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and... | 2 | 2 | 10.6% | 8.1E-4 | 33227 |
[ |
YTA12 | Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation ... | 3 | 3 | 10.5% | 4.31E-4 | 93276 |
[ |
GCD6 | Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchang... | 3 | 3 | 10.5% | 5.0E-4 | 81161 |
[ |
LAG1 | Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydro... | 2 | 2 | 10.5% | 5.77E-4 | 48455 |
[ |
SIR3 | Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a t... | 4 | 4 | 10.4% | 4.85E-4 | 111360 |
[ |
SET4 | Protein of unknown function, contains a SET domain | 2 | 2 | 10.4% | 4.24E-4 | 63856 |
[ |
MTG1 | Putative GTPase peripheral to the mitochondrial inner membrane, essential for respiratory competence... | 2 | 2 | 10.4% | 6.47E-4 | 42145 |
[ |
NOC2 | Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well ... | 2 | 2 | 10.3% | 3.34E-4 | 81601 |
[ |
VPS17 | Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde prote... | 4 | 4 | 10.3% | 8.61E-4 | 63204 |
[ |
CDC14 | Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR ... | 2 | 2 | 10.3% | 4.31E-4 | 61907 |
[ |
COR1 | Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of ... | 2 | 2 | 10.3% | 5.19E-4 | 50228 |
[ |
YPR1 | NADPH-dependent aldo-keto reductase, reduces multiple substrates including 2-methylbutyraldehyde and... | 2 | 2 | 10.3% | 7.6E-4 | 34755 |
[ |
GUF1 | Mitochondrial matrix GTPase that associates with mitochondrial ribosomes; important for translation ... | 2 | 2 | 10.2% | 3.68E-4 | 73188 |
[ |
ECM10 | Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protei... | 3 | 4 | 10.2% | 7.37E-4 | 70085 |
[ |
YGL114W | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family ... | 4 | 4 | 10.1% | 6.55E-4 | 80009 |
[ |
MET17 | Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for s... | 2 | 2 | 10.1% | 5.34E-4 | 48672 |
[ |
TLG2 | Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-deri... | 2 | 2 | 10.1% | 5.98E-4 | 45876 |
[ |
GTS1 | Arf3p GTPase Activating Protein (GAP) that localizes to endocytic patches; gts1 mutations affect bud... | 2 | 2 | 10.1% | 5.99E-4 | 44407 |
[ |
YDL119C | Putative mitochondrial transport protein; GFP-fusion protein is induced in response to the DNA-damag... | 2 | 2 | 10.1% | 7.73E-4 | 34204 |
[ |
PEP12 | Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus... | 2 | 2 | 10.1% | 8.24E-4 | 33006 |
[ |
TFP1 | Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein prec... | 5 | 5 | 10.0% | 5.54E-4 | 118637 |
[ |
YHR003C | Protein of unknown function, localized to the mitochondrial outer membrane | 2 | 2 | 10.0% | 5.53E-4 | 48883 |
[ |
PDR12 | Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter re... | 6 | 6 | 9.9% | 4.71E-4 | 171064 |
[ |
TOF1 | Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled rep... | 3 | 3 | 9.9% | 2.87E-4 | 141120 |
[ |
PEP7 | Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring h... | 2 | 2 | 9.9% | 4.61E-4 | 59443 |
[ |
CTI6 | Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recru... | 2 | 2 | 9.9% | 4.69E-4 | 57053 |
[ |
ABD1 | Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN t... | 2 | 2 | 9.9% | 5.44E-4 | 50341 |
[ |
YAP6 | Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithi... | 2 | 2 | 9.9% | 6.2E-4 | 43597 |
[ |
YOX1 | Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs... | 2 | 2 | 9.9% | 6.16E-4 | 42739 |
[ |
LRO1 | Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that c... | 3 | 3 | 9.8% | 5.38E-4 | 75393 |
[ |
ECM38 | Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of elec... | 2 | 2 | 9.8% | 3.6E-4 | 73181 |
[ |
YKR023W | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... | 2 | 2 | 9.8% | 4.48E-4 | 60799 |
[ |
MAS2 | Larger subunit of the mitochondrial processing protease (MPP), essential processing enzyme that clea... | 2 | 2 | 9.8% | 4.92E-4 | 53338 |
[ |
TEF1, TEF2 | Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... | 3 | 3 | 9.8% | 7.77E-4 | 50033 |
[ |
MSW1 | Mitochondrial tryptophanyl-tRNA synthetase | 2 | 2 | 9.8% | 6.26E-4 | 43015 |
[ |
VAC8 | Phosphorylated and palmitoylated vacuolar membrane protein that interacts with Atg13p, required for ... | 2 | 2 | 9.7% | 4.11E-4 | 63208 |
[ |
NCS2 | Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs... | 2 | 2 | 9.7% | 4.81E-4 | 56473 |
[ |
RIO1 | Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into m... | 2 | 2 | 9.7% | 4.9E-4 | 56122 |
[ |
MLH1 | Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis;... | 2 | 2 | 9.6% | 3.09E-4 | 87062 |
[ |
TPD3 | Regulatory subunit A of the heterotrimeric protein phosphatase 2A (PP2A), which also contains regula... | 4 | 4 | 9.6% | 7.47E-4 | 70907 |
[ |
YSC83 | Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking betwee... | 2 | 2 | 9.6% | 6.16E-4 | 44235 |
[ |
ECM32 | DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is... | 4 | 4 | 9.5% | 4.23E-4 | 126970 |
[ |
DBP10 | Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal... | 4 | 4 | 9.5% | 4.77E-4 | 113158 |
[ |
KEL2 | Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with T... | 5 | 5 | 9.5% | 6.73E-4 | 99975 |
[ |
FRE1 | Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to u... | 2 | 2 | 9.5% | 3.46E-4 | 78854 |
[ |
ELP3 | Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhi... | 2 | 2 | 9.5% | 4.26E-4 | 63657 |
[ |
AGP3 | Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in ... | 3 | 3 | 9.5% | 6.38E-4 | 61052 |
[ |
TIM44 | Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); tethers ... | 2 | 2 | 9.5% | 5.51E-4 | 48854 |
[ |
NUP1 | Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possibl... | 4 | 4 | 9.4% | 4.41E-4 | 113581 |
[ |
VPS70 | Protein of unknown function involved in vacuolar protein sorting | 2 | 2 | 9.4% | 2.93E-4 | 92018 |
[ |
YHL008C | Putative protein of unknown function, may be involved in the uptake of chloride ions; does not appea... | 2 | 2 | 9.4% | 3.78E-4 | 69969 |
[ |
MRK1 | Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that functio... | 3 | 3 | 9.4% | 7.1E-4 | 57819 |
[ |
LSP1 | Primary component of eisosomes, which are large immobile patch structures at the cell cortex associa... | 2 | 2 | 9.4% | 6.96E-4 | 38071 |
[ |
TCB1 | Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localiz... | 4 | 4 | 9.3% | 4.0E-4 | 133576 |
[ |
YOL157C | Putative protein of unknown function | 2 | 2 | 9.3% | 4.03E-4 | 68625 |
[ |
YIL172C, FSP2 | Putative protein of unknown function with similarity to glucosidases; green fluorescent protein (GFP... | 2 | 2 | 9.3% | 4.03E-4 | 68699 |
[ |
BDP1 | Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcri... | 2 | 2 | 9.3% | 3.99E-4 | 67688 |
[ |
LRE1 | Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinas... | 2 | 2 | 9.3% | 4.07E-4 | 64792 |
[ |
POP4 | Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursor... | 2 | 2 | 9.3% | 8.5E-4 | 32881 |
[ |
BNI4 | Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localizatio... | 3 | 3 | 9.2% | 3.99E-4 | 100590 |
[ |
CST6 | Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, proposed to be a regulator ... | 3 | 3 | 9.2% | 6.06E-4 | 65264 |
[ |
SHM2 | Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrof... | 2 | 2 | 9.2% | 5.06E-4 | 52219 |
[ |
BCS1 | Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required f... | 3 | 3 | 9.2% | 7.8E-4 | 51108 |
[ |
SUP45 | Polypeptide release factor (eRF1) in translation termination; mutant form acts as a recessive omnipo... | 3 | 3 | 9.2% | 8.14E-4 | 49006 |
[ |
STE4 | G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a ... | 2 | 2 | 9.2% | 5.61E-4 | 46581 |
[ |
CBK1 | Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall bi... | 2 | 2 | 9.1% | 3.14E-4 | 86946 |
[ |
HOM3 | Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in ... | 2 | 2 | 9.1% | 4.5E-4 | 58110 |
[ |
GDI1 | GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissoc... | 2 | 2 | 9.1% | 5.26E-4 | 51206 |
[ |
YJR107W | Putative protein of unknown function; has sequence or structural similarity to lipases | 2 | 2 | 9.1% | 7.23E-4 | 37261 |
[ |
TGL4 | Multifunctional triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A... | 4 | 4 | 9.0% | 5.21E-4 | 102716 |
[ |
GRS1 | Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bea... | 4 | 4 | 9.0% | 7.11E-4 | 75411 |
[ |
TPO4 | Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasm... | 2 | 2 | 9.0% | 3.6E-4 | 73223 |
[ |
ARB1 | ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has sim... | 2 | 2 | 9.0% | 3.89E-4 | 68377 |
[ |
TPO3 | Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the m... | 3 | 3 | 9.0% | 5.72E-4 | 68066 |
[ |
AUR1 | Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid ... | 2 | 2 | 9.0% | 5.92E-4 | 45193 |
[ |
USV1 | Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regula... | 2 | 2 | 9.0% | 6.07E-4 | 43518 |
[ |
STR2 | Cystathionine gamma-synthase, converts cysteine into cystathionine | 2 | 2 | 8.9% | 3.71E-4 | 72351 |
[ |
SNU71 | Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counte... | 3 | 3 | 8.9% | 5.74E-4 | 71383 |
[ |
BFR1 | Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segre... | 3 | 3 | 8.9% | 7.57E-4 | 54639 |
[ |
TIF5 | Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to m... | 2 | 2 | 8.9% | 5.86E-4 | 45261 |
[ |
YIL096C | Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit; predi... | 2 | 2 | 8.9% | 7.06E-4 | 39402 |
[ |
ARG3 | Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the ... | 2 | 2 | 8.9% | 7.02E-4 | 37845 |
[ |
SKG3 | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell pe... | 5 | 5 | 8.8% | 5.78E-4 | 114111 |
[ |
CDC5 | Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and ... | 3 | 3 | 8.8% | 5.05E-4 | 81031 |
[ |
MDV1 | Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochond... | 2 | 2 | 8.8% | 3.32E-4 | 80032 |
[ |
RMD9 | Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions sug... | 2 | 2 | 8.8% | 3.67E-4 | 74596 |
[ |
GAA1 | Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anch... | 2 | 2 | 8.8% | 3.86E-4 | 69221 |
[ |
RIM101 | Transcriptional repressor involved in response to pH and in cell wall construction; required for alk... | 2 | 2 | 8.8% | 3.8E-4 | 68232 |
[ |
MDM36 | Protein required for normal mitochondrial morphology and inheritance | 2 | 2 | 8.8% | 4.1E-4 | 64959 |
[ |
ARO8 | Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis | 2 | 2 | 8.8% | 4.75E-4 | 56178 |
[ |
RPO41 | Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; re... | 6 | 6 | 8.7% | 5.27E-4 | 153047 |
[ |
SWI4 | DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert ... | 4 | 4 | 8.7% | 4.34E-4 | 123806 |
[ |
YDR186C | Putative protein of unknown function; may interact with ribosomes, based on co-purification experime... | 3 | 3 | 8.7% | 4.06E-4 | 98331 |
[ |
MRE11 | Subunit of a complex with Rad50p and Xrs2p (MRX complex) that functions in repair of DNA double-stra... | 2 | 2 | 8.7% | 3.43E-4 | 77650 |
[ |
YJL045W | Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxi... | 2 | 2 | 8.7% | 3.74E-4 | 69383 |
[ |
ADY3 | Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structu... | 3 | 3 | 8.6% | 4.51E-4 | 91740 |
[ |
UBP11 | Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins | 3 | 3 | 8.6% | 4.96E-4 | 82703 |
[ |
YTA7 | Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a b... | 5 | 5 | 8.5% | 4.3E-4 | 157406 |
[ |
NUT1 | Component of the RNA polymerase II mediator complex, which is required for transcriptional activatio... | 3 | 3 | 8.5% | 3.14E-4 | 128794 |
[ |
AEP1 | Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synth... | 3 | 3 | 8.5% | 6.87E-4 | 59748 |
[ |
ALD3 | Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred c... | 2 | 2 | 8.5% | 4.69E-4 | 55385 |
[ |
ALD2 | Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; use... | 2 | 2 | 8.5% | 4.69E-4 | 55188 |
[ |
YGR031W | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... | 2 | 2 | 8.5% | 6.94E-4 | 38511 |
[ |
CCC2 | Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytos... | 2 | 2 | 8.4% | 2.36E-4 | 109829 |
[ |
RAD16 | Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleot... | 3 | 3 | 8.4% | 4.51E-4 | 91430 |
[ |
MDL2 | Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, required for respirat... | 2 | 2 | 8.4% | 3.07E-4 | 85137 |
[ |
MSD1 | Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial... | 2 | 2 | 8.4% | 3.61E-4 | 75461 |
[ |
CKI1 | Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kenn... | 3 | 3 | 8.4% | 6.12E-4 | 66317 |
[ |
ABP1 | Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 com... | 2 | 2 | 8.4% | 4.01E-4 | 65576 |
[ |
REF2 | RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation,... | 2 | 2 | 8.4% | 4.45E-4 | 59819 |
[ |
YLR064W | Putative protein of unknown function; highly conserved across species and orthologous to human TMEM3... | 2 | 2 | 8.4% | 8.69E-4 | 32637 |
[ |
ISA1 | Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S protei... | 2 | 2 | 8.4% | 9.49E-4 | 27675 |
[ |
HSP78 | Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotoleranc... | 3 | 3 | 8.3% | 4.39E-4 | 91336 |
[ |
MEF2 | Mitochondrial elongation factor involved in translational elongation | 2 | 2 | 8.3% | 2.9E-4 | 91283 |
[ |
AKR2 | Ankyrin repeat-containing protein similar to Akr1p; member of a family of putative palmitoyltransfer... | 3 | 3 | 8.3% | 4.75E-4 | 85236 |
[ |
MPP10 | Component of the SSU processome and 90S preribosome, required for pre-18S rRNA processing, interacts... | 3 | 3 | 8.3% | 6.0E-4 | 66953 |
[ |
YEL023C | Putative protein of unknown function; expression is increased greatly during sporulation; YEL023C is... | 2 | 2 | 8.2% | 3.48E-4 | 78320 |
[ |
PTK1 | Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine trans... | 2 | 2 | 8.2% | 3.66E-4 | 72062 |
[ |
DAK1 | Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress a... | 2 | 2 | 8.2% | 4.06E-4 | 62207 |
[ |
DIT2 | N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-b... | 2 | 2 | 8.2% | 4.85E-4 | 56071 |
[ |
NSR1 | Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ri... | 2 | 2 | 8.2% | 5.73E-4 | 44535 |
[ |
APN1 | Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by o... | 2 | 2 | 8.2% | 6.47E-4 | 41439 |
[ |
BOI2 | Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence ... | 3 | 3 | 8.1% | 3.42E-4 | 115688 |
[ |
DOT6 | Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD... | 2 | 2 | 8.1% | 3.54E-4 | 73048 |
[ |
ULP1 | Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically r... | 2 | 2 | 8.1% | 3.82E-4 | 72378 |
[ |
DBP9 | ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subuni... | 2 | 2 | 8.1% | 3.99E-4 | 68060 |
[ |
MIG3 | Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inh... | 2 | 2 | 8.1% | 6.02E-4 | 43119 |
[ |
HUL5 | Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins; works in op... | 3 | 3 | 8.0% | 3.91E-4 | 105566 |
[ |
PTR3 | Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses exte... | 2 | 2 | 8.0% | 3.5E-4 | 76286 |
[ |
TAF12 | Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiat... | 2 | 2 | 8.0% | 4.4E-4 | 61073 |
[ |
GCD11 | Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start... | 2 | 2 | 8.0% | 4.5E-4 | 57866 |
[ |
COQ1 | Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesi... | 2 | 2 | 8.0% | 5.02E-4 | 52560 |
[ |
LST4 | Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-... | 3 | 3 | 7.9% | 4.3E-4 | 93359 |
[ |
IPI3 | Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS... | 2 | 2 | 7.9% | 4.28E-4 | 61773 |
[ |
RET2 | Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved... | 2 | 2 | 7.9% | 4.35E-4 | 60628 |
[ |
UFD4 | Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle ... | 4 | 4 | 7.8% | 3.2E-4 | 167842 |
[ |
SMC1 | Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation an... | 5 | 5 | 7.8% | 4.84E-4 | 141280 |
[ |
ILS1 | Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A | 2 | 2 | 7.8% | 2.21E-4 | 122983 |
[ |
CCR4 | Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expressio... | 2 | 2 | 7.8% | 2.83E-4 | 94670 |
[ |
VTC4 | Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) comp... | 3 | 3 | 7.8% | 4.94E-4 | 83155 |
[ |
MLH2 | Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic ... | 3 | 3 | 7.8% | 5.12E-4 | 78248 |
[ |
FAA3 | Long chain fatty acyl-CoA synthetase, activates imported fatty acids; green fluorescent protein (GFP... | 2 | 2 | 7.8% | 3.42E-4 | 77947 |
[ |
FRE7 | Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels | 2 | 2 | 7.8% | 3.77E-4 | 71997 |
[ |
SLF1 | RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA trans... | 2 | 2 | 7.8% | 5.31E-4 | 50943 |
[ |
PTC7 | Type 2C protein phosphatase; YHR076W is alternatively spliced to create two mRNA isoforms; protein f... | 2 | 2 | 7.8% | 6.34E-4 | 41191 |
[ |
SPT7 | Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; ... | 3 | 3 | 7.7% | 2.67E-4 | 152617 |
[ |
GIN4 | Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-depen... | 3 | 3 | 7.7% | 3.12E-4 | 129858 |
[ |
RIA1 | Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongat... | 2 | 2 | 7.7% | 2.14E-4 | 124464 |
[ |
NMA111 | Serine protease and general molecular chaperone; involved in response to heat stress and promotion o... | 3 | 3 | 7.7% | 3.57E-4 | 110881 |
[ |
MCM3 | Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin ... | 2 | 2 | 7.7% | 2.44E-4 | 107517 |
[ |
ADE5,7 | Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole... | 2 | 2 | 7.7% | 2.96E-4 | 86068 |
[ |
ARG2 | Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the fi... | 2 | 2 | 7.7% | 4.13E-4 | 65610 |
[ |
CLN2 | G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S p... | 3 | 3 | 7.7% | 6.53E-4 | 61697 |
[ |
STT4 | Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for norma... | 4 | 4 | 7.6% | 2.5E-4 | 214605 |
[ |
RPM2 | Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitoch... | 4 | 5 | 7.6% | 4.93E-4 | 139348 |
[ |
OSH3 | Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members ha... | 5 | 5 | 7.6% | 5.96E-4 | 113760 |
[ |
GAL10 | UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galacto... | 2 | 2 | 7.6% | 3.39E-4 | 78195 |
[ |
AI5_ALPHA | Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mit... | 2 | 2 | 7.6% | 3.77E-4 | 72165 |
[ |
EMI2 | Non-essential protein of unknown function required for transcriptional induction of the early meioti... | 2 | 2 | 7.6% | 4.75E-4 | 55921 |
[ |
ATP2 | Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily c... | 2 | 2 | 7.6% | 4.64E-4 | 54794 |
[ |
SNQ2 | Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug ... | 4 | 4 | 7.5% | 3.16E-4 | 168766 |
[ |
YFR016C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 3 | 3 | 7.5% | 2.89E-4 | 137698 |
[ |
SLN1 | Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intra... | 5 | 5 | 7.5% | 4.86E-4 | 134435 |
[ |
EFT2, EFT1 | Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... | 3 | 3 | 7.5% | 4.23E-4 | 93289 |
[ |
VID27 | Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not esse... | 3 | 3 | 7.5% | 4.55E-4 | 88846 |
[ |
PAP2 | Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP co... | 2 | 2 | 7.5% | 4.06E-4 | 66031 |
[ |
ATH1 | Acid trehalase required for utilization of extracellular trehalose | 3 | 3 | 7.4% | 2.94E-4 | 136920 |
[ |
NMD2 | Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; ... | 4 | 4 | 7.4% | 4.36E-4 | 126747 |
[ |
TPS2 | Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the... | 2 | 2 | 7.4% | 2.65E-4 | 102976 |
[ |
ERG7 | Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a s... | 2 | 2 | 7.4% | 3.25E-4 | 83461 |
[ |
SST2 | GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also requi... | 2 | 2 | 7.4% | 3.4E-4 | 79716 |
[ |
YVC1 | Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic sho... | 2 | 2 | 7.4% | 3.52E-4 | 77953 |
[ |
AIM21 | Protein of unknown function involved in mitochondrial migration along actin filament; may interact w... | 2 | 2 | 7.4% | 3.49E-4 | 74763 |
[ |
PRP40 | U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the for... | 2 | 2 | 7.4% | 4.07E-4 | 69065 |
[ |
DNL4 | DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cof... | 3 | 3 | 7.3% | 3.77E-4 | 108515 |
[ |
SEC23 | GTPase-activating protein, stimulates the GTPase activity of Sar1p; component of the Sec23p-Sec24p h... | 2 | 2 | 7.3% | 3.09E-4 | 85385 |
[ |
DRS1 | Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S r... | 3 | 3 | 7.3% | 4.73E-4 | 84843 |
[ |
RAD27 | 5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation ... | 2 | 2 | 7.3% | 6.21E-4 | 43279 |
[ |
BRO1 | Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the m... | 2 | 2 | 7.2% | 2.81E-4 | 97276 |
[ |
MSR1 | Mitochondrial arginyl-tRNA synthetase | 3 | 3 | 7.2% | 5.54E-4 | 73694 |
[ |
FRS2 | Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form activ... | 2 | 2 | 7.2% | 4.72E-4 | 57511 |
[ |
STB3 | Ribosomal RNA processing element (RRPE)-binding protein involved in the induction of non-ribosomal p... | 2 | 2 | 7.2% | 4.63E-4 | 56264 |
[ |
MRPL3 | Mitochondrial ribosomal protein of the large subunit | 2 | 2 | 7.2% | 6.08E-4 | 44000 |
[ |
MDH1 | Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved i... | 2 | 2 | 7.2% | 7.1E-4 | 35650 |
[ |
HSL1 | Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates wit... | 2 | 2 | 7.1% | 1.56E-4 | 169592 |
[ |
GIP3 | Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromo... | 5 | 5 | 7.1% | 4.65E-4 | 140891 |
[ |
ASK10 | Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a... | 4 | 4 | 7.1% | 4.14E-4 | 126864 |
[ |
NTH2 | Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellula... | 2 | 2 | 7.1% | 3.04E-4 | 89679 |
[ |
IVY1 | Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the... | 2 | 2 | 7.1% | 5.24E-4 | 49976 |
[ |
NEW1 | ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the s... | 4 | 4 | 7.0% | 3.97E-4 | 134331 |
[ |
IFH1 | Coactivator that regulates transcription of ribosomal protein (RP) genes; recruited to RP gene promo... | 3 | 4 | 7.0% | 4.37E-4 | 122491 |
[ |
RPG1 | eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translati... | 2 | 2 | 7.0% | 2.46E-4 | 110344 |
[ |
SBE22 | Protein involved in the transport of cell wall components from the Golgi to the cell surface; simila... | 2 | 2 | 7.0% | 2.78E-4 | 96398 |
[ |
UBP1 | Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C ter... | 2 | 2 | 7.0% | 2.93E-4 | 92769 |
[ |
HPR1 | Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and wi... | 2 | 2 | 7.0% | 3.16E-4 | 87829 |
[ |
PRP43 | RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript... | 2 | 2 | 7.0% | 3.09E-4 | 87562 |
[ |
MNT3 | Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-link... | 3 | 3 | 7.0% | 5.65E-4 | 72410 |
[ |
MTG2 | Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane th... | 2 | 2 | 7.0% | 4.75E-4 | 55537 |
[ |
ALD6 | Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; re... | 2 | 2 | 7.0% | 4.75E-4 | 54414 |
[ |
RIF1 | Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telom... | 4 | 4 | 6.9% | 2.48E-4 | 217959 |
[ |
VAS1 | Mitochondrial and cytoplasmic valyl-tRNA synthetase | 3 | 3 | 6.9% | 3.22E-4 | 125770 |
[ |
TRP5 | Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general co... | 2 | 2 | 6.9% | 3.36E-4 | 76626 |
[ |
BSP1 | Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton | 2 | 2 | 6.9% | 4.12E-4 | 64666 |
[ |
CCT8 | Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of... | 2 | 2 | 6.9% | 4.18E-4 | 61662 |
[ |
EDC3 | Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically ... | 2 | 2 | 6.9% | 4.31E-4 | 61340 |
[ |
SEN54 | Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p | 2 | 2 | 6.9% | 5.08E-4 | 54649 |
[ |
ZUO1 | Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a ch... | 2 | 2 | 6.9% | 5.48E-4 | 49020 |
[ |
RRG8 | Putative protein of unknown function, required for mitochondrial genome maintenance; null mutation r... | 2 | 2 | 6.9% | 8.57E-4 | 31133 |
[ |
ROD1 | Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers r... | 2 | 2 | 6.8% | 2.83E-4 | 92349 |
[ |
RUD3 | Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically... | 2 | 2 | 6.8% | 4.9E-4 | 56069 |
[ |
RNT1 | RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure a... | 2 | 2 | 6.8% | 5.04E-4 | 54071 |
[ |
PRP8 | Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutation... | 7 | 7 | 6.7% | 3.44E-4 | 279502 |
[ |
DNF1 | Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contribute... | 4 | 4 | 6.7% | 3.02E-4 | 177797 |
[ |
MYO3 | One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect o... | 3 | 3 | 6.7% | 2.8E-4 | 142507 |
[ |
TDA9 | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 3 | 3 | 6.7% | 2.84E-4 | 141465 |
[ |
PMR1 | High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in C... | 3 | 3 | 6.7% | 3.75E-4 | 104571 |
[ |
CDC4 | F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a comp... | 2 | 2 | 6.7% | 3.05E-4 | 86090 |
[ |
KAR2 | ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... | 3 | 4 | 6.7% | 6.96E-4 | 74468 |
[ |
NDC1 | Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore com... | 3 | 3 | 6.7% | 5.43E-4 | 74134 |
[ |
CRP1 | Protein that binds to cruciform DNA structures | 2 | 2 | 6.7% | 5.1E-4 | 51116 |
[ |
SWH1 | Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the G... | 4 | 4 | 6.6% | 3.99E-4 | 135070 |
[ |
SEF1 | Putative transcription factor, has homolog in Kluyveromyces lactis | 3 | 3 | 6.6% | 3.1E-4 | 127992 |
[ |
YEF3 | Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes b... | 4 | 4 | 6.6% | 4.55E-4 | 115945 |
[ |
UBA1 | Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential f... | 2 | 2 | 6.6% | 2.32E-4 | 114266 |
[ |
PHO87 | Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression... | 2 | 2 | 6.6% | 2.57E-4 | 102540 |
[ |
EBS1 | Protein involved in inhibition of translation and nonsense-mediated decay; interacts with cap bindin... | 2 | 2 | 6.6% | 2.68E-4 | 100000 |
[ |
ACE2 | Transcription factor that activates expression of early G1-specific genes, localizes to daughter cel... | 3 | 3 | 6.6% | 4.62E-4 | 86634 |
[ |
EAP1 | eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translati... | 2 | 2 | 6.6% | 3.75E-4 | 69762 |
[ |
MRS6 | Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the pr... | 2 | 2 | 6.6% | 3.93E-4 | 67374 |
[ |
DED1 | ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all ye... | 2 | 2 | 6.6% | 3.93E-4 | 65553 |
[ |
BIT2 | Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during po... | 2 | 2 | 6.6% | 4.35E-4 | 61302 |
[ |
LCB3 | Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulat... | 2 | 2 | 6.6% | 5.8E-4 | 47372 |
[ |
KEM1 | Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved i... | 3 | 3 | 6.5% | 2.33E-4 | 175459 |
[ |
STH1 | ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic g... | 4 | 4 | 6.5% | 3.49E-4 | 156742 |
[ |
VPS54 | Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, wh... | 2 | 2 | 6.5% | 2.67E-4 | 101520 |
[ |
VPS72 | Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chroma... | 2 | 2 | 6.5% | 2.98E-4 | 90580 |
[ |
RLM1 | MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involve... | 2 | 2 | 6.5% | 3.51E-4 | 73484 |
[ |
PHR1 | DNA photolyase involved in photoreactivation, repairs pyrimidine dimers in the presence of visible l... | 2 | 3 | 6.5% | 6.3E-4 | 66274 |
[ |
HRD1 | Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfold... | 2 | 2 | 6.5% | 4.31E-4 | 63535 |
[ |
YHR080C | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 4 | 4 | 6.4% | 3.53E-4 | 149679 |
[ |
SSD1 | Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathw... | 4 | 4 | 6.4% | 3.8E-4 | 139954 |
[ |
KAP123 | Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and... | 2 | 2 | 6.4% | 2.13E-4 | 122601 |
[ |
JSN1 | Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated ... | 4 | 4 | 6.4% | 4.35E-4 | 120374 |
[ |
CYM1 | Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin f... | 3 | 3 | 6.4% | 3.6E-4 | 112180 |
[ |
CDC13 | Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication ... | 3 | 3 | 6.4% | 3.85E-4 | 104904 |
[ |
SBE2 | Protein involved in the transport of cell wall components from the Golgi to the cell surface; requir... | 2 | 2 | 6.4% | 2.75E-4 | 98971 |
[ |
VPS1 | Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization,... | 2 | 2 | 6.4% | 3.37E-4 | 78736 |
[ |
PBS2 | MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activate... | 2 | 2 | 6.4% | 3.55E-4 | 72720 |
[ |
DOT1 | Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic che... | 2 | 2 | 6.4% | 4.08E-4 | 66201 |
[ |
FRT2 | Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a subs... | 2 | 2 | 6.4% | 4.49E-4 | 58750 |
[ |
CYR1 | Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAM... | 4 | 4 | 6.3% | 2.34E-4 | 227832 |
[ |
NUP188 | Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex an... | 4 | 4 | 6.3% | 2.87E-4 | 188576 |
[ |
ECM21 | Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrat... | 2 | 2 | 6.3% | 2.12E-4 | 123609 |
[ |
RDH54 | DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; i... | 2 | 2 | 6.3% | 2.57E-4 | 104153 |
[ |
HIR2 | Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene tra... | 2 | 2 | 6.3% | 2.71E-4 | 98445 |
[ |
BRE1 | E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is requi... | 2 | 2 | 6.3% | 3.39E-4 | 80692 |
[ |
NOP58 | Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the ... | 2 | 2 | 6.3% | 4.64E-4 | 56956 |
[ |
INO80 | ATPase, subunit of a complex containing actin and several actin-related proteins that has chromatin ... | 4 | 4 | 6.2% | 3.19E-4 | 171454 |
[ |
INP53 | Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in t... | 4 | 4 | 6.2% | 4.29E-4 | 124577 |
[ |
PRP16 | RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-... | 2 | 2 | 6.2% | 2.22E-4 | 121652 |
[ |
YFL034W | Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal ... | 3 | 3 | 6.2% | 3.32E-4 | 119496 |
[ |
SRO7 | Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis a... | 2 | 2 | 6.2% | 2.3E-4 | 114513 |
[ |
PFK1 | Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaer... | 3 | 3 | 6.2% | 3.61E-4 | 107970 |
[ |
SCY1 | Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase | 2 | 2 | 6.2% | 2.95E-4 | 91001 |
[ |
URC2 | Putative Zn(II)2Cys6 motif containing transcription factor; non-essential gene identified in a scree... | 2 | 2 | 6.2% | 3.07E-4 | 88648 |
[ |
SIR2 | Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespa... | 3 | 3 | 6.2% | 6.33E-4 | 63262 |
[ |
UTR1 | ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of fer... | 2 | 2 | 6.2% | 4.48E-4 | 59469 |
[ |
KGD1 | Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step... | 2 | 2 | 6.1% | 2.34E-4 | 114416 |
[ |
TMA108 | Protein that associates with ribosomes; putative metalloprotease | 3 | 3 | 6.1% | 3.76E-4 | 107723 |
[ |
STE13 | Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repe... | 2 | 2 | 6.1% | 2.55E-4 | 107200 |
[ |
UTP21 | Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in pr... | 2 | 2 | 6.1% | 2.53E-4 | 104791 |
[ |
YRM1 | Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; par... | 2 | 2 | 6.1% | 3.02E-4 | 91084 |
[ |
NSP1 | Essential component of the nuclear pore complex, which mediates nuclear import and export, found in ... | 3 | 3 | 6.1% | 4.32E-4 | 86516 |
[ |
KIN82 | Putative serine/threonine protein kinase implicated in the regulation of phospholipid asymmetry thro... | 2 | 2 | 6.1% | 3.3E-4 | 81494 |
[ |
ESBP6 | Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of mon... | 2 | 2 | 6.1% | 3.53E-4 | 73802 |
[ |
MCM10 | Essential chromatin-associated protein involved in the initiation of DNA replication; required for t... | 2 | 2 | 6.1% | 4.16E-4 | 65815 |
[ |
CDC25 | Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates ... | 4 | 4 | 6.0% | 2.99E-4 | 179091 |
[ |
ADE6 | Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucle... | 4 | 4 | 6.0% | 3.49E-4 | 148904 |
[ |
PUF2 | Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that ... | 4 | 4 | 6.0% | 4.41E-4 | 119508 |
[ |
POL5 | DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-t... | 2 | 2 | 6.0% | 2.32E-4 | 115894 |
[ |
APL3 | Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle ... | 2 | 2 | 6.0% | 2.31E-4 | 115012 |
[ |
NIP100 | Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between... | 2 | 2 | 6.0% | 2.73E-4 | 100290 |
[ |
PXA1 | Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), requi... | 2 | 2 | 6.0% | 2.73E-4 | 100025 |
[ |
NIC96 | Component of the nuclear pore complex, required for nuclear pore formation; forms a subcomplex with ... | 2 | 2 | 6.0% | 2.83E-4 | 96174 |
[ |
YER184C | Putative zinc cluster protein; deletion confers sensitivity to Calcufluor white, and prevents growth... | 2 | 2 | 6.0% | 2.99E-4 | 91077 |
[ |
TSR1 | Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal ... | 2 | 2 | 6.0% | 3.01E-4 | 90748 |
[ |
LDB19 | Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquit... | 2 | 2 | 6.0% | 2.9E-4 | 89826 |
[ |
SLI15 | Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regula... | 2 | 2 | 6.0% | 3.4E-4 | 79186 |
[ |
NOP4 | Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subun... | 2 | 2 | 6.0% | 3.46E-4 | 77825 |
[ |
GRS2 | Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for ... | 2 | 2 | 6.0% | 3.84E-4 | 71019 |
[ |
RMA1 | Putative dihydrofolate synthetase; has similarity to Fol3p and to E. coli folylpolyglutamate synthet... | 2 | 2 | 6.0% | 5.52E-4 | 48143 |
[ |
BNI1 | Formin, nucleates the formation of linear actin filaments, involved in cell processes such as buddin... | 5 | 5 | 5.9% | 3.04E-4 | 219701 |
[ |
CHC1 | Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport ... | 4 | 4 | 5.9% | 2.87E-4 | 187233 |
[ |
OXP1 | 5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green... | 3 | 3 | 5.9% | 2.77E-4 | 140427 |
[ |
CTR9 | Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II;... | 2 | 2 | 5.9% | 2.2E-4 | 124655 |
[ |
AKL1 | Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocyto... | 3 | 3 | 5.9% | 3.21E-4 | 123989 |
[ |
YBL104C | Putative protein of unknown function, promoter contains multiple GCN4 binding sites | 2 | 2 | 5.9% | 2.29E-4 | 117636 |
[ |
STB2 | Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with ... | 2 | 2 | 5.9% | 2.79E-4 | 97828 |
[ |
BCK2 | Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which ... | 2 | 2 | 5.9% | 2.79E-4 | 93738 |
[ |
APL4 | Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; invo... | 2 | 2 | 5.9% | 2.85E-4 | 93624 |
[ |
YGR237C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 3 | 3 | 5.9% | 4.53E-4 | 89241 |
[ |
SPT21 | Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not... | 2 | 2 | 5.9% | 3.13E-4 | 84697 |
[ |
EST1 | TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the ... | 3 | 3 | 5.9% | 5.09E-4 | 81800 |
[ |
CDC1 | Putative lipid phosphatase of the endoplasmic reticulum; shows Mn2+ dependence and may affect Ca2+ s... | 2 | 2 | 5.9% | 4.83E-4 | 57147 |
[ |
CDC50 | Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essent... | 2 | 2 | 5.9% | 6.07E-4 | 44982 |
[ |
ESP1 | Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating di... | 5 | 5 | 5.8% | 3.64E-4 | 187445 |
[ |
KHA1 | Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Gol... | 2 | 2 | 5.8% | 2.72E-4 | 97111 |
[ |
AIM44 | Protein of unknown function; GFP-fusion protein localizes to the bud neck; transcription is regulate... | 2 | 2 | 5.8% | 3.13E-4 | 84846 |
[ |
AFG3 | Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation... | 2 | 2 | 5.8% | 3.12E-4 | 84544 |
[ |
YAP1 | Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated ... | 2 | 2 | 5.8% | 3.65E-4 | 72533 |
[ |
BZZ1 | SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polym... | 2 | 2 | 5.8% | 3.75E-4 | 71171 |
[ |
DCC1 | Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, re... | 2 | 2 | 5.8% | 6.24E-4 | 44074 |
[ |
REV3 | Catalytic subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication ... | 3 | 3 | 5.7% | 2.37E-4 | 172956 |
[ |
TUS1 | Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the ce... | 2 | 2 | 5.7% | 1.82E-4 | 149112 |
[ |
YOR296W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 5.7% | 1.84E-4 | 147426 |
[ |
GDE1 | Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphospha... | 3 | 3 | 5.7% | 2.91E-4 | 138014 |
[ |
YAK1 | Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control ... | 3 | 3 | 5.7% | 4.41E-4 | 91245 |
[ |
GTB1 | Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two gl... | 2 | 2 | 5.7% | 3.38E-4 | 79908 |
[ |
YPR045C | Protein of unknown function; involvement in splicing based on pre-mRNA accumulation defect for many ... | 2 | 2 | 5.7% | 5.05E-4 | 53719 |
[ |
SPA2 | Component of the polarisome, which functions in actin cytoskeletal organization during polarized gro... | 3 | 3 | 5.6% | 2.43E-4 | 163142 |
[ |
RAV1 | Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym... | 3 | 3 | 5.6% | 2.62E-4 | 154932 |
[ |
GEF1 | Voltage-gated chloride channel localized to the golgi, the endosomal system, and plasma membrane, an... | 2 | 2 | 5.6% | 3.05E-4 | 87592 |
[ |
YJL132W | Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated t... | 2 | 2 | 5.6% | 3.16E-4 | 84466 |
[ |
SMY1 | Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-terminal domain is relat... | 2 | 2 | 5.6% | 3.62E-4 | 73799 |
[ |
SAC3 | Nuclear pore-associated protein, required for biogenesis of the small ribosomal subunit; forms a com... | 2 | 2 | 5.5% | 1.82E-4 | 149568 |
[ |
MSH6 | Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair bo... | 3 | 3 | 5.5% | 2.87E-4 | 140080 |
[ |
ISW2 | ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, f... | 2 | 2 | 5.5% | 2.12E-4 | 130327 |
[ |
MSH3 | Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutati... | 3 | 3 | 5.5% | 3.4E-4 | 119753 |
[ |
MDR1 | Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involve... | 2 | 2 | 5.5% | 2.5E-4 | 109259 |
[ |
DIP2 | Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein c... | 2 | 2 | 5.5% | 2.52E-4 | 106342 |
[ |
GPH1 | Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulate... | 2 | 2 | 5.5% | 2.63E-4 | 103275 |
[ |
MDM20 | Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes N-acetylation of pro... | 2 | 2 | 5.5% | 2.98E-4 | 92809 |
[ |
CEX1 | Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nu... | 2 | 2 | 5.5% | 3.12E-4 | 84769 |
[ |
GPT2 | Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located... | 3 | 3 | 5.5% | 4.79E-4 | 83645 |
[ |
AGP2 | High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down... | 2 | 2 | 5.5% | 3.98E-4 | 67262 |
[ |
CET1 | Beta (RNA 5'-triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is... | 2 | 2 | 5.5% | 4.32E-4 | 61850 |
[ |
SMM1 | Dihydrouridine synthase, member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3... | 2 | 2 | 5.5% | 6.18E-4 | 42816 |
[ |
POL2 | Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhi... | 5 | 5 | 5.4% | 2.67E-4 | 255669 |
[ |
SPP41 | Protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3 | 2 | 2 | 5.4% | 1.65E-4 | 161596 |
[ |
RET1 | Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and... | 2 | 2 | 5.4% | 2.07E-4 | 129456 |
[ |
YMR196W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 3 | 3 | 5.4% | 3.27E-4 | 126624 |
[ |
ALY1 | Protein proposed to regulate the endocytosis of plasma membrane proteins by recruiting the ubiquitin... | 3 | 3 | 5.4% | 3.89E-4 | 102540 |
[ |
HIR1 | Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene tra... | 2 | 2 | 5.4% | 2.82E-4 | 93890 |
[ |
ACS2 | Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histo... | 3 | 3 | 5.4% | 5.21E-4 | 75492 |
[ |
THI20 | Multifunctional protein with hydroxymethylpyrimidine phosphate (HMP-P) kinase and thiaminase activit... | 2 | 2 | 5.4% | 4.31E-4 | 61269 |
[ |
BFR2 | Essential protein that is a component of 90S preribosomes; may be involved in rRNA processing; multi... | 2 | 2 | 5.4% | 4.44E-4 | 61203 |
[ |
UTP20 | Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA | 6 | 6 | 5.3% | 2.86E-4 | 287559 |
[ |
MAK5 | Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA vir... | 2 | 2 | 5.3% | 3.07E-4 | 87048 |
[ |
YMR085W | Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains | 2 | 2 | 5.3% | 5.49E-4 | 48502 |
[ |
GCN1 | Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate ... | 7 | 7 | 5.2% | 3.11E-4 | 296697 |
[ |
SEC3 | Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which me... | 3 | 3 | 5.2% | 2.66E-4 | 154694 |
[ |
PIK1 | Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-... | 3 | 3 | 5.2% | 3.34E-4 | 119923 |
[ |
FUN12 | GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes a... | 3 | 3 | 5.2% | 3.55E-4 | 112268 |
[ |
SKT5 | Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p;... | 2 | 2 | 5.2% | 3.41E-4 | 77066 |
[ |
YDR266C | Protein of unknown function that may interact with ribosomes, based on co-purification experiments;g... | 3 | 3 | 5.2% | 5.57E-4 | 72756 |
[ |
RAD2 | Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to e... | 2 | 2 | 5.1% | 2.3E-4 | 117838 |
[ |
SFI1 | Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the ... | 3 | 3 | 5.1% | 3.76E-4 | 112978 |
[ |
KAR9 | Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplas... | 2 | 2 | 5.1% | 3.68E-4 | 74245 |
[ |
TRM1 | tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localiz... | 2 | 2 | 5.1% | 4.16E-4 | 64052 |
[ |
JLP1 | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use... | 2 | 2 | 5.1% | 5.76E-4 | 46983 |
[ |
DNF2 | Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contribute... | 4 | 4 | 5.0% | 2.94E-4 | 182617 |
[ |
TTI1 | Putative protein of unknown function; subunit of the ASTRA complex which is part of the chromatin re... | 3 | 3 | 5.0% | 3.43E-4 | 118889 |
[ |
TIF4631 | Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that al... | 2 | 2 | 5.0% | 2.49E-4 | 107101 |
[ |
SOV1 | Mitochondrial protein of unknown function | 2 | 2 | 5.0% | 2.64E-4 | 104748 |
[ |
PIF1 | DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation... | 2 | 2 | 5.0% | 2.76E-4 | 97682 |
[ |
HIS4 | Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrol... | 2 | 2 | 5.0% | 2.97E-4 | 87721 |
[ |
GSH1 | Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expres... | 2 | 2 | 5.0% | 3.5E-4 | 78254 |
[ |
SDH1 | Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxid... | 2 | 2 | 5.0% | 3.71E-4 | 70229 |
[ |
SNF2 | Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation... | 5 | 5 | 4.9% | 3.48E-4 | 194050 |
[ |
RPA190 | RNA polymerase I largest subunit A190 | 4 | 4 | 4.9% | 2.85E-4 | 186431 |
[ |
THO2 | Subunit of the THO complex, which is required for efficient transcription elongation and involved in... | 2 | 2 | 4.9% | 1.49E-4 | 183930 |
[ |
POM152 | Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore... | 3 | 3 | 4.9% | 2.66E-4 | 151652 |
[ |
TRS120 | One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates... | 2 | 2 | 4.9% | 1.84E-4 | 147662 |
[ |
SPO71 | Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; ... | 2 | 2 | 4.9% | 1.91E-4 | 145181 |
[ |
ENA1 | P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance | 3 | 3 | 4.9% | 3.26E-4 | 120357 |
[ |
STE20 | Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family; involved in phe... | 2 | 2 | 4.9% | 2.53E-4 | 102362 |
[ |
SEC27 | Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport... | 2 | 2 | 4.9% | 2.67E-4 | 99445 |
[ |
TYW1 | Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adja... | 2 | 2 | 4.9% | 2.93E-4 | 89805 |
[ |
RAD4 | Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subun... | 2 | 2 | 4.9% | 3.15E-4 | 87204 |
[ |
BOP2 | Protein of unknown function | 2 | 2 | 4.9% | 4.16E-4 | 66344 |
[ |
ARO1 | Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which i... | 4 | 4 | 4.8% | 2.99E-4 | 174754 |
[ |
HER1 | Protein of unknown function required for proliferation or remodeling of the ER that is caused by ove... | 2 | 2 | 4.8% | 1.9E-4 | 139457 |
[ |
NFT1 | Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs Y... | 3 | 3 | 4.8% | 2.92E-4 | 137996 |
[ |
YPR097W | Protein that contains a Phox homology (PX) domain and binds phosphoinositides; the authentic, non-ta... | 2 | 2 | 4.8% | 2.21E-4 | 123054 |
[ |
CDC15 | Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anap... | 2 | 2 | 4.8% | 2.44E-4 | 110285 |
[ |
FLC1 | Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wa... | 2 | 2 | 4.8% | 2.99E-4 | 89291 |
[ |
QNS1 | Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid ade... | 2 | 2 | 4.8% | 3.32E-4 | 80686 |
[ |
RMD8 | Cytosolic protein required for sporulation | 2 | 2 | 4.8% | 3.58E-4 | 75914 |
[ |
CYS3 | Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathw... | 2 | 2 | 4.8% | 6.02E-4 | 42542 |
[ |
SUL2 | High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p an... | 3 | 3 | 4.7% | 3.99E-4 | 99651 |
[ |
SYH1 | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 2 | 2 | 4.7% | 2.79E-4 | 94356 |
[ |
BCH2 | Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), t... | 2 | 3 | 4.7% | 4.65E-4 | 88044 |
[ |
LAP4 | Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often... | 2 | 2 | 4.7% | 4.62E-4 | 57093 |
[ |
NUP192 | Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery o... | 3 | 3 | 4.6% | 2.11E-4 | 191534 |
[ |
PEP1 | Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golg... | 2 | 2 | 4.6% | 1.5E-4 | 177777 |
[ |
ATG26 | UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside m... | 3 | 3 | 4.6% | 2.97E-4 | 136054 |
[ |
RTT107 | Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation ... | 2 | 2 | 4.6% | 2.22E-4 | 123017 |
[ |
CIN1 | Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased... | 2 | 2 | 4.6% | 2.34E-4 | 116648 |
[ |
HSH155 | U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice... | 2 | 2 | 4.6% | 2.44E-4 | 110028 |
[ |
GFA1 | Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glut... | 3 | 3 | 4.6% | 4.96E-4 | 80047 |
[ |
RAD24 | Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; ... | 2 | 2 | 4.6% | 3.6E-4 | 75727 |
[ |
TMA64 | Protein of unknown function that associates with ribosomes; has a putative RNA binding domain | 2 | 2 | 4.6% | 4.2E-4 | 63992 |
[ |
BRR2 | RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in nativ... | 3 | 3 | 4.5% | 1.65E-4 | 246183 |
[ |
CAT8 | Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fe... | 2 | 2 | 4.5% | 1.66E-4 | 160485 |
[ |
MIP1 | Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for ... | 2 | 2 | 4.5% | 1.89E-4 | 143502 |
[ |
FUN30 | Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Sn... | 2 | 2 | 4.5% | 2.1E-4 | 128507 |
[ |
HBT1 | Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); m... | 2 | 2 | 4.5% | 2.27E-4 | 113616 |
[ |
MCM2 | Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin ... | 2 | 2 | 4.5% | 2.73E-4 | 98779 |
[ |
ARG5,6 | Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-gl... | 2 | 2 | 4.5% | 2.75E-4 | 94869 |
[ |
SAP4 | Protein required for function of the Sit4p protein phosphatase, member of a family of similar protei... | 2 | 2 | 4.5% | 2.9E-4 | 94729 |
[ |
WHI4 | Putative RNA binding protein and partially redundant Whi3p homolog that regulates the cell size requ... | 2 | 2 | 4.5% | 3.66E-4 | 70690 |
[ |
ACK1 | Protein that functions upstream of Pkc1p in the cell wall integrity pathway; GFP-fusion protein expr... | 2 | 2 | 4.5% | 3.81E-4 | 69371 |
[ |
ORC1 | Largest subunit of the origin recognition complex, which directs DNA replication by binding to repli... | 2 | 2 | 4.4% | 2.6E-4 | 104400 |
[ |
PUF3 | Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anter... | 2 | 2 | 4.4% | 2.7E-4 | 98068 |
[ |
MCM7 | Component of the hexameric MCM complex, which is important for priming origins of DNA replication in... | 2 | 2 | 4.4% | 2.81E-4 | 94875 |
[ |
IRC8 | Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent tran... | 2 | 2 | 4.4% | 2.89E-4 | 91256 |
[ |
CTF3 | Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to s... | 2 | 2 | 4.4% | 3.24E-4 | 84252 |
[ |
PXL1 | LIM domain-containing protein that localizes to sites of polarized growth, required for selection an... | 2 | 2 | 4.4% | 3.36E-4 | 79448 |
[ |
SMF2 | Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valen... | 2 | 2 | 4.4% | 4.32E-4 | 59768 |
[ |
COP1 | Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secr... | 2 | 2 | 4.3% | 1.98E-4 | 135607 |
[ |
KIN2 | Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic f... | 3 | 3 | 4.3% | 3.1E-4 | 128338 |
[ |
VAC7 | Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p k... | 2 | 2 | 4.3% | 2.04E-4 | 128140 |
[ |
RAT1 | Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snR... | 2 | 2 | 4.3% | 2.36E-4 | 115934 |
[ |
MSH1 | DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity... | 2 | 2 | 4.3% | 2.47E-4 | 109408 |
[ |
IMH1 | Protein involved in vesicular transport, mediates transport between an endosomal compartment and the... | 2 | 2 | 4.3% | 2.6E-4 | 105225 |
[ |
COS111 | Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtel... | 2 | 2 | 4.3% | 2.57E-4 | 104505 |
[ |
OAF3 | Zinc cluster protein; regulates transcription in response to oleate levels; the authentic, non-tagge... | 2 | 2 | 4.3% | 2.75E-4 | 101825 |
[ |
YIL092W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 4.3% | 3.75E-4 | 71006 |
[ |
ARO9 | Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine ca... | 2 | 2 | 4.3% | 4.63E-4 | 58528 |
[ |
SMC4 | Subunit of the condensin complex; reorganizes chromosomes during cell division; forms a complex with... | 3 | 3 | 4.2% | 2.51E-4 | 162188 |
[ |
EDS1 | Putative zinc cluster protein; YBR033W is not an essential gene | 2 | 2 | 4.2% | 2.58E-4 | 103397 |
[ |
PRT1 | eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translati... | 2 | 2 | 4.2% | 3.11E-4 | 88130 |
[ |
MLH3 | Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a comp... | 2 | 2 | 4.2% | 3.32E-4 | 82001 |
[ |
NUM1 | Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may med... | 5 | 5 | 4.1% | 2.16E-4 | 313032 |
[ |
YJR029W | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 4.1% | 2.03E-4 | 198616 |
[ |
YBL005W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 4.1% | 2.03E-4 | 198968 |
[ |
YMR045C | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 4.1% | 2.03E-4 | 198898 |
[ |
YGR027W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 4.1% | 2.03E-4 | 198656 |
[ |
YNL284C-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 4.1% | 2.03E-4 | 198997 |
[ |
BPT1 | ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the t... | 2 | 2 | 4.1% | 1.52E-4 | 176873 |
[ |
PSK1 | One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein... | 2 | 2 | 4.1% | 1.75E-4 | 152330 |
[ |
KEL1 | Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to ne... | 2 | 2 | 4.1% | 2.04E-4 | 131094 |
[ |
HSP104 | Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate pre... | 2 | 2 | 4.1% | 2.61E-4 | 102035 |
[ |
ZIP1 | Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recom... | 2 | 2 | 4.1% | 2.71E-4 | 100035 |
[ |
COG6 | Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering com... | 3 | 3 | 4.1% | 4.24E-4 | 96976 |
[ |
PRP5 | RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNP... | 2 | 2 | 4.1% | 2.79E-4 | 96359 |
[ |
IOC3 | Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses ... | 2 | 2 | 4.1% | 3.01E-4 | 90897 |
[ |
NOC3 | Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate th... | 2 | 2 | 4.1% | 3.58E-4 | 75582 |
[ |
SSC1 | Hsp70 family ATPase, constituent of the import motor component of the Translocase of the Inner Mitoc... | 3 | 4 | 4.1% | 7.26E-4 | 70628 |
[ |
DBP1 | Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability o... | 2 | 2 | 4.1% | 3.85E-4 | 67917 |
[ |
RIT1 | 2'-O-ribosyl phosphate transferase, modifies the initiator methionine tRNA at position 64 to disting... | 2 | 2 | 4.1% | 4.63E-4 | 58882 |
[ |
MOT1 | Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA vi... | 3 | 3 | 4.0% | 1.91E-4 | 209975 |
[ |
YCF1 | Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detox... | 2 | 2 | 4.0% | 1.57E-4 | 171120 |
[ |
SNT2 | DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a ... | 3 | 3 | 4.0% | 2.54E-4 | 163203 |
[ |
NST1 | Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the spli... | 2 | 2 | 4.0% | 1.91E-4 | 141514 |
[ |
KSP1 | Ser/thr protein kinase; nuclear translocation required for haploid filamentous growth; regulates fil... | 2 | 2 | 4.0% | 2.31E-4 | 117082 |
[ |
MPH1 | Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that in... | 2 | 2 | 4.0% | 2.39E-4 | 114058 |
[ |
NUP85 | Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for assembly of the sub... | 2 | 2 | 4.0% | 3.19E-4 | 84898 |
[ |
MSC6 | Protein of unknown function; mutant is defective in directing meiotic recombination events to homolo... | 2 | 2 | 4.0% | 3.43E-4 | 79947 |
[ |
NDT80 | Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombin... | 2 | 2 | 4.0% | 3.78E-4 | 71480 |
[ |
HFA1 | Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondria... | 3 | 3 | 3.9% | 1.68E-4 | 241784 |
[ |
RPO21 | RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapep... | 3 | 3 | 3.9% | 2.05E-4 | 191610 |
[ |
MYO4 | One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; requi... | 2 | 2 | 3.9% | 1.61E-4 | 169343 |
[ |
NCR1 | Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, i... | 2 | 2 | 3.9% | 2.03E-4 | 132645 |
[ |
KIN1 | Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic f... | 2 | 2 | 3.9% | 2.23E-4 | 120071 |
[ |
ZRG8 | Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondr... | 2 | 3 | 3.9% | 3.31E-4 | 119350 |
[ |
REV1 | Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p;... | 2 | 2 | 3.9% | 2.41E-4 | 112227 |
[ |
YDR514C | Putative protein of unknown function | 2 | 2 | 3.9% | 4.91E-4 | 55490 |
[ |
LTV1 | Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; req... | 2 | 2 | 3.9% | 5.12E-4 | 53390 |
[ |
TSC11 | Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates... | 3 | 3 | 3.8% | 2.49E-4 | 164368 |
[ |
PDR18 | Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resist... | 3 | 3 | 3.8% | 2.67E-4 | 149750 |
[ |
YOL036W | Protein of unknown function; potential Cdc28p substrate | 2 | 2 | 3.8% | 3.12E-4 | 84352 |
[ |
PPZ2 | Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transp... | 2 | 2 | 3.8% | 3.34E-4 | 78492 |
[ |
ARE1 | Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the... | 2 | 2 | 3.8% | 3.89E-4 | 71613 |
[ |
IRA1 | GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bo... | 5 | 5 | 3.7% | 1.92E-4 | 350980 |
[ |
FMP27 | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... | 3 | 3 | 3.7% | 1.35E-4 | 303478 |
[ |
FAB1 | 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylino... | 3 | 3 | 3.7% | 1.56E-4 | 257447 |
[ |
FAS2 | Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty ... | 3 | 3 | 3.7% | 1.89E-4 | 206945 |
[ |
CHD1 | Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a ch... | 2 | 2 | 3.7% | 1.62E-4 | 168240 |
[ |
BCK1 | Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathwa... | 3 | 3 | 3.7% | 2.41E-4 | 164195 |
[ |
SGS1 | Nucleolar DNA helicase of the RecQ family involved in genome integrity maintenance; regulates chromo... | 2 | 2 | 3.7% | 1.64E-4 | 163837 |
[ |
ALY2 | Protein proposed to regulate the endocytosis of plasma membrane proteins; interacts with the cyclin ... | 2 | 2 | 3.7% | 2.27E-4 | 117216 |
[ |
ULP2 | Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion ... | 3 | 3 | 3.7% | 3.44E-4 | 116882 |
[ |
KAP114 | Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino termin... | 2 | 2 | 3.7% | 2.36E-4 | 113921 |
[ |
DIS3 | Exosome core complex catalytic subunit; possesses both endonuclease and 3'-5' exonuclease activity; ... | 2 | 2 | 3.7% | 2.37E-4 | 113707 |
[ |
ALP1 | Arginine transporter; expression is normally very low and it is unclear what conditions would induce... | 2 | 2 | 3.7% | 4.14E-4 | 64014 |
[ |
GAT1 | Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-typ... | 2 | 2 | 3.7% | 4.65E-4 | 56328 |
[ |
YIL082W-A | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 3.7% | 2.38E-4 | 172454 |
[ |
MYO1 | Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the... | 3 | 3 | 3.6% | 1.85E-4 | 223634 |
[ |
CMR2 | Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-induc... | 2 | 2 | 3.6% | 1.44E-4 | 186906 |
[ |
MYO2 | One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; requi... | 2 | 2 | 3.6% | 1.51E-4 | 180679 |
[ |
YGR109W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 3.6% | 2.3E-4 | 178419 |
[ |
OSH2 | Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members ha... | 4 | 4 | 3.6% | 3.7E-4 | 145796 |
[ |
HMG2 | One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in... | 3 | 3 | 3.6% | 3.41E-4 | 115692 |
[ |
MET10 | Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide | 2 | 2 | 3.6% | 2.29E-4 | 114829 |
[ |
PIP2 | Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)... | 2 | 2 | 3.6% | 2.38E-4 | 114710 |
[ |
FLO5 | Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the s... | 2 | 2 | 3.6% | 2.21E-4 | 111981 |
[ |
PWP2 | Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA... | 2 | 2 | 3.6% | 2.57E-4 | 103983 |
[ |
SSK22 | MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; functionally redundant wit... | 2 | 2 | 3.5% | 1.78E-4 | 152717 |
[ |
STE6 | Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyze... | 2 | 2 | 3.5% | 1.84E-4 | 144765 |
[ |
SIP3 | Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has... | 2 | 2 | 3.5% | 1.93E-4 | 142819 |
[ |
SMC3 | Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells;... | 2 | 2 | 3.5% | 1.93E-4 | 141336 |
[ |
MTR4 | ATP-dependent 3'-5' RNA helicase, involved in nuclear RNA processing and degredation both as a compo... | 2 | 2 | 3.5% | 2.21E-4 | 122055 |
[ |
PFK2 | Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaero... | 2 | 2 | 3.5% | 2.47E-4 | 104618 |
[ |
DEF1 | RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and prot... | 2 | 2 | 3.5% | 3.22E-4 | 83973 |
[ |
PDS5 | Protein required for establishment and maintenance of sister chromatid condensation and cohesion, co... | 2 | 2 | 3.4% | 1.86E-4 | 147041 |
[ |
CHS2 | Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of ... | 2 | 2 | 3.4% | 2.46E-4 | 109882 |
[ |
RPN1 | Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the... | 2 | 2 | 3.4% | 2.39E-4 | 109492 |
[ |
GIS1 | JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes... | 2 | 2 | 3.4% | 2.65E-4 | 99481 |
[ |
SAS3 | Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in ... | 2 | 2 | 3.4% | 2.86E-4 | 97582 |
[ |
UBP10 | Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing ... | 2 | 2 | 3.4% | 3.0E-4 | 88517 |
[ |
GCR1 | Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and fu... | 2 | 2 | 3.4% | 3.02E-4 | 87729 |
[ |
VPS13 | Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated wit... | 4 | 4 | 3.3% | 1.51E-4 | 357850 |
[ |
MEC1 | Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for... | 2 | 2 | 3.3% | 1.0E-4 | 273340 |
[ |
GSC2 | Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore... | 3 | 3 | 3.3% | 1.88E-4 | 216988 |
[ |
IQG1 | Essential protein required for determination of budding pattern, promotes localization of axial mark... | 2 | 2 | 3.3% | 1.59E-4 | 172830 |
[ |
AUS1 | Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth | 2 | 2 | 3.3% | 1.7E-4 | 157750 |
[ |
PKH2 | Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls en... | 2 | 2 | 3.3% | 2.19E-4 | 121660 |
[ |
USA1 | Protein involved in ER-associated protein degradation (ERAD); component of the Hrd1p complex; intera... | 2 | 2 | 3.3% | 2.83E-4 | 96653 |
[ |
CDC53 | Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box pr... | 2 | 2 | 3.3% | 2.91E-4 | 93944 |
[ |
MSS116 | DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar ... | 2 | 2 | 3.3% | 3.57E-4 | 76269 |
[ |
DNA2 | Tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease,... | 2 | 2 | 3.2% | 1.56E-4 | 171694 |
[ |
CFT1 | RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recogn... | 2 | 2 | 3.2% | 1.75E-4 | 153404 |
[ |
SLA1 | Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; inter... | 2 | 2 | 3.2% | 1.91E-4 | 135848 |
[ |
YCS4 | Subunit of the condensin complex; required for establishment and maintenance of chromosome condensat... | 2 | 2 | 3.2% | 2.02E-4 | 132967 |
[ |
PRP22 | DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates befor... | 2 | 2 | 3.2% | 2.07E-4 | 130010 |
[ |
RIM15 | Glucose-repressible protein kinase involved in signal transduction during cell proliferation in resp... | 3 | 3 | 3.1% | 2.01E-4 | 196530 |
[ |
DOP1 | Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, ... | 3 | 3 | 3.1% | 2.1E-4 | 194686 |
[ |
GDB1 | Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, ... | 3 | 3 | 3.1% | 2.32E-4 | 174971 |
[ |
LYS2 | Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-... | 2 | 2 | 3.1% | 1.7E-4 | 155345 |
[ |
ADR1 | Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose... | 2 | 2 | 3.1% | 1.79E-4 | 150941 |
[ |
TCB2 | Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from... | 2 | 2 | 3.1% | 2.01E-4 | 132509 |
[ |
PKC1 | Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites... | 2 | 2 | 3.1% | 2.06E-4 | 131519 |
[ |
REG1 | Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-r... | 2 | 2 | 3.1% | 2.34E-4 | 112616 |
[ |
FOX2 | Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA d... | 2 | 2 | 3.1% | 2.64E-4 | 98703 |
[ |
FAS1 | Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty a... | 2 | 2 | 3.0% | 1.16E-4 | 228689 |
[ |
STU1 | Component of the mitotic spindle that binds to interpolar microtubules via its association with beta... | 3 | 3 | 3.0% | 2.35E-4 | 174176 |
[ |
MMS22 | Protein that acts with Mms1p in a repair pathway that may be involved in resolving replication inter... | 2 | 2 | 3.0% | 1.63E-4 | 167682 |
[ |
BMS1 | GTPase required for synthesis of 40S ribosomal subunits and for processing the 35S pre-rRNA at sites... | 2 | 2 | 3.0% | 2.01E-4 | 135571 |
[ |
APC1 | Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein li... | 2 | 2 | 2.9% | 1.36E-4 | 196143 |
[ |
SCC2 | Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes... | 2 | 2 | 2.9% | 1.59E-4 | 171101 |
[ |
ESL2 | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 2 | 2 | 2.9% | 1.99E-4 | 137491 |
[ |
TFC4 | One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part... | 2 | 2 | 2.9% | 2.31E-4 | 120229 |
[ |
GLT1 | NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglut... | 2 | 2 | 2.8% | 1.11E-4 | 238100 |
[ |
KOG1 | Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or To... | 2 | 2 | 2.8% | 1.52E-4 | 177608 |
[ |
BUD4 | Protein involved in bud-site selection and required for axial budding pattern; localizes with septin... | 2 | 2 | 2.8% | 1.64E-4 | 165023 |
[ |
ASE1 | Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for s... | 2 | 2 | 2.8% | 2.68E-4 | 101624 |
[ |
IRA2 | GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bo... | 5 | 5 | 2.7% | 1.93E-4 | 351669 |
[ |
FKS1 | Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... | 3 | 3 | 2.7% | 1.9E-4 | 214849 |
[ |
IML1 | Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuola... | 2 | 2 | 2.7% | 1.5E-4 | 181948 |
[ |
MDM1 | Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds;... | 2 | 2 | 2.7% | 2.11E-4 | 129981 |
[ |
HEF3 | Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates ... | 2 | 2 | 2.7% | 2.27E-4 | 115869 |
[ |
TOR2 | PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth i... | 2 | 2 | 2.6% | 9.59E-5 | 281566 |
[ |
PAN1 | Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on th... | 2 | 2 | 2.6% | 1.6E-4 | 160266 |
[ |
RPB2 | RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subun... | 2 | 2 | 2.6% | 1.94E-4 | 138751 |
[ |
UBR2 | Cytoplasmic ubiquitin-protein ligase (E3); required for ubiquitylation of Rpn4p; mediates formation ... | 2 | 2 | 2.5% | 1.27E-4 | 216777 |
[ |
RPO31 | RNA polymerase III largest subunit C160, part of core enzyme; similar to bacterial beta-prime subuni... | 2 | 2 | 2.5% | 1.63E-4 | 162301 |
[ |
BUL1 | Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, d... | 2 | 7 | 2.5% | 8.51E-4 | 109174 |
[ |
APE2 | Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; sequence coord... | 2 | 2 | 2.5% | 2.54E-4 | 105585 |
[ |
HAP1 | Zinc finger transcription factor involved in the complex regulation of gene expression in response t... | 2 | 2 | 2.4% | 1.58E-4 | 166107 |
[ |
TOP2 | Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the pho... | 2 | 2 | 2.4% | 1.66E-4 | 164214 |
[ |
SWI1 | Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chr... | 2 | 2 | 2.4% | 1.81E-4 | 147937 |
[ |
MRC1 | S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stal... | 2 | 2 | 2.4% | 2.16E-4 | 124326 |
[ |
UBP7 | Ubiquitin-specific protease that cleaves ubiquitin-protein fusions | 2 | 2 | 2.4% | 2.22E-4 | 123134 |
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MGM1 | Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required f... | 2 | 2 | 2.4% | 2.63E-4 | 101523 |
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YPR158C-D | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.3% | 1.35E-4 | 198373 |
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VTH2 | Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in ... | 2 | 2 | 2.3% | 1.53E-4 | 174401 |
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VTH1 | Putative membrane glycoprotein with strong similarity to Vth2p and Pep1p/Vps10p, may be involved in ... | 2 | 2 | 2.3% | 1.53E-4 | 174427 |
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GEA1 | Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transp... | 2 | 2 | 2.3% | 1.69E-4 | 159437 |
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TRK1 | Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter... | 2 | 2 | 2.3% | 1.92E-4 | 141073 |
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VMR1 | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 2 | 2 | 2.2% | 1.49E-4 | 180925 |
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RAD50 | Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in ve... | 2 | 2 | 2.2% | 1.81E-4 | 152568 |
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SAP1 | Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hyb... | 2 | 2 | 2.2% | 2.65E-4 | 100332 |
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MDN1 | Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex... | 5 | 5 | 2.1% | 1.21E-4 | 559316 |
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TOR1 | PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in... | 4 | 4 | 2.1% | 1.92E-4 | 281138 |
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URA2 | Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes t... | 3 | 3 | 2.1% | 1.61E-4 | 245123 |
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USO1 | Essential protein involved in the vesicle-mediated ER to Golgi transport step of secretion; binds me... | 2 | 2 | 2.1% | 1.33E-4 | 206450 |
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NTE1 | Serine esterase, homolog of human neuropathy target esterase (NTE); Nte1p-mediated phosphatidylcholi... | 2 | 2 | 2.1% | 1.41E-4 | 187132 |
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SEC16 | COPII vesicle coat protein required for ER transport vesicle budding; Sec16p is bound to the periphe... | 2 | 2 | 1.9% | 1.08E-4 | 241694 |
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CDC39 | Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regu... | 3 | 3 | 1.9% | 1.69E-4 | 240277 |
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GCN2 | Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in re... | 2 | 2 | 1.9% | 1.43E-4 | 190193 |
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GEA2 | Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transp... | 2 | 2 | 1.9% | 1.63E-4 | 165667 |
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BEM2 | Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cell... | 2 | 2 | 1.8% | 1.09E-4 | 245428 |
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YJL113W | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 1.8% | 1.32E-4 | 207708 |
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CHS3 | Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for ... | 2 | 2 | 1.8% | 2.04E-4 | 131601 |
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APL5 | Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport... | 2 | 2 | 1.8% | 2.55E-4 | 106924 |
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AI1 | Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intro... | 2 | 2 | 1.8% | 2.84E-4 | 96079 |
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FLO9 | Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation | 2 | 2 | 1.5% | 1.79E-4 | 138072 |
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DYN1 | Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation;... | 3 | 3 | 1.4% | 8.7E-5 | 471351 |
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CSF1 | Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected ... | 4 | 4 | 1.4% | 1.6E-4 | 338258 |
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YLR422W | Protein of unknown function with similarity to human DOCK proteins (guanine nucleotide exchange fact... | 2 | 2 | 1.4% | 1.23E-4 | 221562 |
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PMD1 | Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expr... | 2 | 2 | 1.4% | 1.35E-4 | 195382 |