Bait Protein: | MLP2 |
Organism: | Saccharomyces cerevisiae |
Publication: | Keck JM, Jones MH, Wong CC, Binkley J, Chen D, Jaspersen SL, Holinger EP, Xu T, Niepel M, Rout MP, Vogel J, Sidow A, Yates JR, Winey M., A Cell Cycle Phosphoproteome of the Yeast Centrosome, Science 24 June 2011: 1557-1561. |
Comments: | #29 Asynchronous Prep5-TiO2 Flowthrough |
Raw Data: |
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FILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
YIL002W-A | Putative protein of unknown function; identified by expression profiling and mass spectrometry | 31 | 32 | 92.8% | 0.0873 | 7729 |
[ |
CMD1 | Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, act... | 12 | 13 | 85.0% | 0.0166 | 16135 |
[ |
MLP2 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 257 | 294 | 84.2% | 0.033 | 195140 |
[ |
SPC42 | Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate att... | 51 | 60 | 81.0% | 0.0311 | 42271 |
[ |
SPC110 | Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nu... | 137 | 152 | 78.2% | 0.0303 | 111782 |
[ |
CDC31 | Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication i... | 17 | 18 | 76.4% | 0.021 | 18751 |
[ |
SPC29 | Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inn... | 18 | 19 | 74.3% | 0.0141 | 29280 |
[ |
CNM67 | Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclea... | 66 | 72 | 66.6% | 0.0233 | 67400 |
[ |
DCI1 | Peroxisomal protein; identification as a delta(3,5)-delta(2,4)-dienoyl-CoA isomerase involved in fat... | 3 | 3 | 44.6% | 0.00208 | 30058 |
[ |
ATP5 | Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserv... | 3 | 3 | 44.3% | 0.00266 | 22814 |
[ |
BFA1 | Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pa... | 20 | 23 | 41.5% | 0.00754 | 66087 |
[ |
ATP20 | Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosp... | 2 | 2 | 34.8% | 0.00327 | 12921 |
[ |
NUD1 | Component of the spindle pole body outer plaque, required for exit from mitosis | 28 | 30 | 34.2% | 0.00664 | 94104 |
[ |
GPI15 | Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the firs... | 2 | 2 | 34.1% | 0.00164 | 26817 |
[ |
HTB1 | Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly id... | 2 | 2 | 28.2% | 0.00287 | 14252 |
[ |
HTB2 | Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly id... | 2 | 2 | 28.2% | 0.00287 | 14237 |
[ |
DOG1 | 2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight... | 2 | 2 | 26.8% | 0.00153 | 27100 |
[ |
RRP15 | Nucleolar protein, constituent of pre-60S ribosomal particles; required for proper processing of the... | 2 | 2 | 25.6% | 0.00151 | 28212 |
[ |
BUD20 | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of ... | 2 | 2 | 24.1% | 0.00227 | 18517 |
[ |
COX10 | Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A pr... | 2 | 2 | 23.8% | 8.15E-4 | 52148 |
[ |
HPA3 | D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mec... | 2 | 2 | 22.9% | 0.0021 | 20699 |
[ |
MUM2 | Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, whi... | 4 | 4 | 21.0% | 0.00206 | 41433 |
[ |
MRPL20 | Mitochondrial ribosomal protein of the large subunit | 2 | 2 | 21.0% | 0.00193 | 22392 |
[ |
YSR3 | Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; ha... | 3 | 3 | 20.5% | 0.0014 | 46488 |
[ |
SSF2 | Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member o... | 2 | 2 | 20.3% | 8.31E-4 | 51856 |
[ |
NFU1 | Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required fo... | 3 | 3 | 19.9% | 0.00221 | 29174 |
[ |
CDC14 | Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR ... | 5 | 5 | 19.2% | 0.00171 | 61907 |
[ |
MTF2 | Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymeras... | 3 | 3 | 18.9% | 0.00128 | 51192 |
[ |
NTR2 | Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box ... | 2 | 2 | 18.3% | 0.00117 | 36647 |
[ |
ARG8 | Acetylornithine aminotransferase, catalyzes the fourth step in the biosynthesis of the arginine prec... | 2 | 2 | 18.2% | 8.9E-4 | 46681 |
[ |
YML037C | Putative protein of unknown function with some characteristics of a transcriptional activator; may b... | 2 | 2 | 17.9% | 0.00111 | 38023 |
[ |
NOP8 | Nucleolar protein required for 60S ribosomal subunit biogenesis | 3 | 3 | 17.8% | 0.00117 | 56966 |
[ |
YNR048W | Protein that interacts specifically in vivo with phospholipid translocase (flippase) Dnf3p; similar ... | 2 | 2 | 17.8% | 9.58E-4 | 44542 |
[ |
YJR107W | Putative protein of unknown function; has sequence or structural similarity to lipases | 2 | 2 | 17.7% | 0.00115 | 37261 |
[ |
NKP1 | Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-O... | 2 | 2 | 17.6% | 0.00158 | 26976 |
[ |
TIM23 | Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved... | 2 | 2 | 17.6% | 0.0017 | 23244 |
[ |
RDR1 | Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expr... | 3 | 3 | 17.4% | 0.00103 | 61287 |
[ |
MOD5 | Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the mod... | 3 | 3 | 16.6% | 0.00132 | 50237 |
[ |
BNI5 | Protein involved in organization of septins at the mother-bud neck, may interact directly with the C... | 2 | 2 | 16.3% | 8.4E-4 | 49694 |
[ |
ADE12 | Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from ino... | 3 | 3 | 16.2% | 0.0013 | 48279 |
[ |
COX18 | Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p... | 2 | 2 | 16.1% | 0.00119 | 35650 |
[ |
SUI3 | Beta subunit of the translation initiation factor eIF2, involved in the identification of the start ... | 2 | 2 | 16.1% | 0.00132 | 31574 |
[ |
NBP1 | Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuc... | 3 | 3 | 16.0% | 0.00177 | 37354 |
[ |
MOB2 | Component of the RAM signaling network, that activates the Cbk1p kinase, thereby facilitating the Ac... | 2 | 2 | 15.7% | 0.00131 | 33276 |
[ |
PAM16 | Constituent of the import motor (PAM complex) component of the Translocase of the Inner Mitochondria... | 2 | 2 | 15.4% | 0.00253 | 16216 |
[ |
STE7 | Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, ... | 2 | 2 | 15.3% | 7.31E-4 | 57709 |
[ |
ADE16 | Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotid... | 3 | 3 | 15.2% | 9.56E-4 | 65283 |
[ |
HSP60 | Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides... | 2 | 2 | 15.2% | 6.58E-4 | 60752 |
[ |
YKR018C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 3 | 3 | 15.0% | 7.79E-4 | 81754 |
[ |
IPL1 | Aurora kinase subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p)... | 2 | 2 | 15.0% | 0.00103 | 42946 |
[ |
TOF2 | Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase act... | 4 | 4 | 14.9% | 9.77E-4 | 86366 |
[ |
PPZ1 | Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transp... | 2 | 2 | 14.9% | 5.44E-4 | 77491 |
[ |
ODC1 | Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochond... | 2 | 2 | 14.8% | 0.00121 | 34206 |
[ |
HSP33 | Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, ... | 2 | 2 | 14.8% | 0.00159 | 25926 |
[ |
SHM1 | Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahy... | 2 | 2 | 14.3% | 7.68E-4 | 53686 |
[ |
YDL114W | Putative protein of unknown function with similarity to acyl-carrier-protein reductases; YDL114W is ... | 2 | 2 | 14.3% | 0.00122 | 34295 |
[ |
PEX21 | Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p;... | 2 | 2 | 14.2% | 0.00131 | 33050 |
[ |
YGR210C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 14.1% | 9.16E-4 | 45214 |
[ |
NOP12 | Nucleolar protein involved in pre-25S rRNA processing and biogenesis of large 60S ribosomal subunit;... | 2 | 2 | 13.9% | 8.2E-4 | 51942 |
[ |
YOL107W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 13.7% | 0.0011 | 39742 |
[ |
MEP3 | Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic m... | 2 | 2 | 13.5% | 7.7E-4 | 53690 |
[ |
CMK1 | Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan depend... | 2 | 2 | 13.5% | 8.44E-4 | 50296 |
[ |
TIP41 | Protein that interacts physically and genetically with Tap42p, which regulates protein phosphatase 2... | 2 | 2 | 13.5% | 0.00106 | 41020 |
[ |
AIM44 | Protein of unknown function; GFP-fusion protein localizes to the bud neck; transcription is regulate... | 4 | 4 | 13.3% | 9.93E-4 | 84846 |
[ |
SCW11 | Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based ... | 2 | 2 | 13.3% | 6.95E-4 | 56447 |
[ |
YBL029W | Non-essential protein of unknown function | 2 | 2 | 13.3% | 0.001 | 42604 |
[ |
KCC4 | Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, n... | 4 | 4 | 13.2% | 7.26E-4 | 116475 |
[ |
YGR054W | Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribos... | 2 | 2 | 13.2% | 5.86E-4 | 71305 |
[ |
NMT1 | N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the ... | 2 | 2 | 13.2% | 8.27E-4 | 52838 |
[ |
FRA1 | Protein involved in negative regulation of transcription of iron regulon; forms an iron independent ... | 2 | 2 | 12.7% | 5.03E-4 | 84924 |
[ |
CAD1 | AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron m... | 3 | 3 | 12.5% | 0.00138 | 45752 |
[ |
AIM18 | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... | 2 | 2 | 12.5% | 0.00117 | 36502 |
[ |
PRE10 | Alpha 7 subunit of the 20S proteasome | 2 | 2 | 12.5% | 0.00131 | 31536 |
[ |
ERG12 | Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from m... | 2 | 2 | 12.4% | 8.5E-4 | 48460 |
[ |
TUB4 | Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of th... | 2 | 2 | 12.3% | 7.96E-4 | 52628 |
[ |
YPL068C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus... | 2 | 2 | 12.3% | 0.00128 | 33098 |
[ |
OLA1 | P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacti... | 2 | 2 | 12.2% | 9.56E-4 | 44174 |
[ |
RPC82 | RNA polymerase III subunit C82 | 3 | 3 | 12.1% | 8.63E-4 | 74017 |
[ |
SPC72 | Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them... | 5 | 5 | 12.1% | 0.00151 | 72105 |
[ |
MPC54 | Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytopl... | 2 | 2 | 12.1% | 8.11E-4 | 54358 |
[ |
TAF7 | TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation | 3 | 3 | 12.0% | 9.57E-4 | 67556 |
[ |
SIF2 | WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middl... | 2 | 2 | 12.0% | 7.04E-4 | 59161 |
[ |
HRB1 | Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; sim... | 2 | 2 | 11.9% | 8.78E-4 | 49142 |
[ |
SER1 | 3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyru... | 2 | 2 | 11.9% | 9.53E-4 | 43416 |
[ |
DAK2 | Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress a... | 3 | 3 | 11.7% | 9.56E-4 | 62135 |
[ |
CCM1 | Mitochondrial 15s rRNA-binding protein; required for intron removal of COB and COX1 pre-mRNAs; conta... | 4 | 4 | 11.6% | 8.71E-4 | 101422 |
[ |
SPT20 | Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the... | 2 | 2 | 11.6% | 6.23E-4 | 67797 |
[ |
ROK1 | ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis | 3 | 3 | 11.5% | 0.001 | 63653 |
[ |
PPN1 | Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer | 3 | 3 | 11.4% | 8.38E-4 | 78344 |
[ |
FPR3 | Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by cas... | 2 | 2 | 11.4% | 9.16E-4 | 46553 |
[ |
TYS1 | Cytoplasmic tyrosyl-tRNA synthetase, required for cytoplasmic protein synthesis; interacts with posi... | 2 | 2 | 11.4% | 9.56E-4 | 44020 |
[ |
PPZ2 | Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transp... | 3 | 3 | 11.3% | 7.95E-4 | 78492 |
[ |
ARX1 | Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interact... | 3 | 3 | 11.3% | 9.52E-4 | 65213 |
[ |
PRP31 | Splicing factor, component of the U4/U6-U5 snRNP complex | 2 | 2 | 11.3% | 7.62E-4 | 56303 |
[ |
TMA46 | Protein of unknown function that associates with ribosomes; interacts with GTPase Rbg1p | 2 | 2 | 11.3% | 0.00109 | 39514 |
[ |
MCH2 | Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of m... | 2 | 2 | 11.2% | 7.96E-4 | 52342 |
[ |
SLF1 | RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA trans... | 2 | 2 | 11.2% | 8.42E-4 | 50943 |
[ |
TOK1 | Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of ... | 3 | 3 | 11.1% | 8.17E-4 | 77408 |
[ |
CIK1 | Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts s... | 2 | 2 | 11.1% | 6.34E-4 | 69070 |
[ |
BSP1 | Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton | 3 | 3 | 11.1% | 9.8E-4 | 64666 |
[ |
ILV1 | Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under genera... | 2 | 2 | 11.1% | 6.54E-4 | 63831 |
[ |
CCT8 | Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of... | 2 | 2 | 11.1% | 6.63E-4 | 61662 |
[ |
GOR1 | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic,... | 2 | 2 | 11.1% | 0.00108 | 38831 |
[ |
HOM6 | Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third... | 2 | 2 | 11.1% | 0.00105 | 38502 |
[ |
DIC1 | Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate ... | 2 | 2 | 11.1% | 0.00126 | 32992 |
[ |
FAR1 | Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also for... | 4 | 4 | 11.0% | 9.07E-4 | 94572 |
[ |
TUB1 | Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form... | 2 | 2 | 11.0% | 8.42E-4 | 49800 |
[ |
PSR1 | Plasma membrane associated protein phosphatase involved in the general stress response; required alo... | 2 | 2 | 11.0% | 8.82E-4 | 47931 |
[ |
UTP23 | Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40... | 2 | 2 | 11.0% | 0.00148 | 28801 |
[ |
YJR056C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to bo... | 2 | 2 | 11.0% | 0.0016 | 27361 |
[ |
PPQ1 | Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational su... | 2 | 2 | 10.9% | 6.86E-4 | 61421 |
[ |
TMS1 | Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain ele... | 2 | 2 | 10.8% | 7.96E-4 | 52230 |
[ |
KGD2 | Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase com... | 2 | 2 | 10.8% | 8.13E-4 | 50431 |
[ |
BRF1 | TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor... | 3 | 3 | 10.7% | 9.47E-4 | 66907 |
[ |
SAM1 | S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom ... | 2 | 2 | 10.7% | 9.86E-4 | 41818 |
[ |
CAM1 | Nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other... | 2 | 2 | 10.6% | 9.07E-4 | 47088 |
[ |
OSH7 | Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members ha... | 2 | 2 | 10.5% | 8.61E-4 | 49805 |
[ |
RIB5 | Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway | 2 | 2 | 10.5% | 0.00158 | 26196 |
[ |
MAK10 | Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of ... | 2 | 2 | 10.4% | 5.14E-4 | 84302 |
[ |
MNE1 | Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase | 3 | 3 | 10.4% | 8.52E-4 | 77230 |
[ |
RLF2 | Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles ... | 2 | 2 | 10.4% | 6.21E-4 | 70210 |
[ |
ZUO1 | Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a ch... | 2 | 2 | 10.4% | 8.69E-4 | 49020 |
[ |
SPO1 | Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation... | 2 | 2 | 10.3% | 5.97E-4 | 72187 |
[ |
DOS2 | Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytopla... | 2 | 2 | 10.3% | 0.00121 | 35964 |
[ |
ILV2 | Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is ... | 3 | 3 | 10.2% | 8.22E-4 | 74937 |
[ |
TDA7 | Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p | 3 | 3 | 10.2% | 8.88E-4 | 67357 |
[ |
RSM28 | Mitochondrial ribosomal protein of the small subunit; genetic interactions suggest a possible role i... | 2 | 2 | 10.2% | 0.00104 | 41216 |
[ |
YLR283W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mi... | 2 | 2 | 10.2% | 0.0012 | 36574 |
[ |
FHL1 | Regulator of ribosomal protein transcription; has forkhead associated domain that binds phosphorylat... | 3 | 3 | 10.1% | 6.03E-4 | 103502 |
[ |
YEN1 | Holliday junction resolvase; localization is cell-cycle dependent and regulated by Cdc28p phosphoryl... | 2 | 2 | 10.1% | 4.96E-4 | 87390 |
[ |
MSK1 | Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms... | 2 | 2 | 10.1% | 6.54E-4 | 66128 |
[ |
EBP2 | Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, locali... | 2 | 2 | 10.1% | 8.82E-4 | 49734 |
[ |
YKL050C | Protein of unknown function; the YKL050W protein is a target of the SCFCdc4 ubiquitin ligase complex... | 4 | 4 | 10.0% | 8.17E-4 | 103144 |
[ |
UTP25 | Nucleolar protein that cosediments with the 40S ribosomal subunit and is required for its biogenesis... | 3 | 3 | 10.0% | 7.83E-4 | 83991 |
[ |
AIM21 | Protein of unknown function involved in mitochondrial migration along actin filament; may interact w... | 3 | 3 | 10.0% | 8.32E-4 | 74763 |
[ |
CRZ1 | Transcription factor that activates transcription of genes involved in stress response; nuclear loca... | 2 | 2 | 9.9% | 5.55E-4 | 76301 |
[ |
KIP2 | Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by ta... | 2 | 2 | 9.8% | 5.33E-4 | 78378 |
[ |
ADH2 | Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; i... | 2 | 2 | 9.8% | 0.00108 | 36732 |
[ |
MAG2 | Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated pro... | 3 | 3 | 9.7% | 8.43E-4 | 76317 |
[ |
ATG20 | Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for en... | 2 | 2 | 9.7% | 5.88E-4 | 72546 |
[ |
NSE5 | Essential subunit of the Mms21-Smc5-Smc6 complex; required for cell viability and DNA repair | 2 | 2 | 9.7% | 6.77E-4 | 64013 |
[ |
ZPR1 | Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to th... | 2 | 2 | 9.7% | 7.75E-4 | 55072 |
[ |
TIM44 | Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); tethers ... | 2 | 2 | 9.5% | 8.73E-4 | 48854 |
[ |
AVO2 | Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regu... | 2 | 2 | 9.4% | 8.84E-4 | 47140 |
[ |
AIM24 | Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria ... | 2 | 2 | 9.4% | 9.56E-4 | 44428 |
[ |
MPS1 | Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint func... | 3 | 3 | 9.3% | 7.39E-4 | 86828 |
[ |
MUK1 | Cytoplasmic protein of unknown function containing a Vps9 domain; computational analysis of large-sc... | 2 | 2 | 9.3% | 6.15E-4 | 69539 |
[ |
DIG1 | Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mati... | 2 | 2 | 9.3% | 8.33E-4 | 49356 |
[ |
AIF1 | Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli,... | 3 | 3 | 9.3% | 0.00149 | 41335 |
[ |
GIP3 | Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromo... | 5 | 5 | 9.2% | 7.38E-4 | 140891 |
[ |
SMC6 | Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 comp... | 3 | 3 | 9.2% | 5.07E-4 | 128008 |
[ |
RGR1 | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ... | 3 | 3 | 9.1% | 5.22E-4 | 123358 |
[ |
NTH2 | Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellula... | 2 | 2 | 9.1% | 4.83E-4 | 89679 |
[ |
ATG32 | Mitochondrial-anchored transmembrane receptor that interacts with the autophagy adaptor protein, Atg... | 3 | 3 | 9.1% | 0.00107 | 58969 |
[ |
YBL055C | 3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian ... | 2 | 2 | 9.1% | 9.01E-4 | 47390 |
[ |
MAK32 | Protein necessary for structural stability of L-A double-stranded RNA-containing particles | 2 | 2 | 9.1% | 0.00104 | 40783 |
[ |
NPL4 | Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recog... | 2 | 2 | 9.0% | 6.49E-4 | 65782 |
[ |
SPE4 | Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pa... | 2 | 2 | 9.0% | 0.00125 | 34091 |
[ |
RFX1 | Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p t... | 3 | 3 | 8.9% | 6.96E-4 | 90584 |
[ |
GYL1 | Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gy... | 3 | 3 | 8.9% | 7.84E-4 | 82131 |
[ |
DBP7 | Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis; essenti... | 3 | 3 | 8.8% | 7.61E-4 | 83308 |
[ |
TEC1 | Transcription factor required for full Ty1 expression, Ty1-mediated gene activation, and haploid inv... | 2 | 2 | 8.8% | 7.75E-4 | 55158 |
[ |
TYR1 | Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine... | 3 | 3 | 8.8% | 0.00125 | 50923 |
[ |
RSF2 | Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, man... | 3 | 3 | 8.7% | 4.09E-4 | 155062 |
[ |
MSH1 | DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity... | 3 | 3 | 8.7% | 5.89E-4 | 109408 |
[ |
YPP1 | Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4; ... | 2 | 2 | 8.7% | 4.61E-4 | 95366 |
[ |
YMR031C | Protein of unknown function with similarity to Ykl050cp and Uso1p; the authentic, non-tagged protein... | 5 | 5 | 8.7% | 0.00112 | 93345 |
[ |
IME4 | Probable mRNA N6-adenosine methyltransferase required for entry into meiosis; transcribed in diploid... | 2 | 2 | 8.7% | 6.27E-4 | 69396 |
[ |
SFI1 | Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the ... | 3 | 3 | 8.6% | 5.97E-4 | 112978 |
[ |
IBA57 | Mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondria... | 2 | 2 | 8.5% | 7.57E-4 | 57055 |
[ |
YJL193W | Putative protein of unknown function, predicted to encode a triose phosphate transporter subfamily m... | 2 | 2 | 8.5% | 9.36E-4 | 45937 |
[ |
MLP1 | Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the... | 11 | 11 | 8.4% | 0.0011 | 218454 |
[ |
NNF2 | Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polyme... | 3 | 3 | 8.4% | 6.03E-4 | 106465 |
[ |
SIZ1 | SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to p... | 2 | 2 | 8.4% | 4.16E-4 | 100796 |
[ |
PRP5 | RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNP... | 2 | 2 | 8.4% | 4.43E-4 | 96359 |
[ |
TCO89 | Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates growth in response to... | 3 | 3 | 8.4% | 7.07E-4 | 88845 |
[ |
SNG1 | Protein involved in resistance to nitrosoguanidine (MNNG) and 6-azauracil (6-AU); expression is regu... | 2 | 2 | 8.4% | 6.88E-4 | 61294 |
[ |
RSC1 | Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-s... | 4 | 4 | 8.3% | 8.11E-4 | 106669 |
[ |
LYP1 | Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of c... | 2 | 2 | 8.3% | 6.16E-4 | 68090 |
[ |
HPC2 | Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene tra... | 2 | 2 | 8.3% | 6.04E-4 | 67517 |
[ |
AFG1 | Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochr... | 2 | 2 | 8.3% | 7.4E-4 | 58265 |
[ |
SAS2 | Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acet... | 2 | 2 | 8.3% | 0.00111 | 39206 |
[ |
PDR10 | ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resis... | 5 | 5 | 8.2% | 6.02E-4 | 176460 |
[ |
PBP1 | Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assem... | 3 | 3 | 8.2% | 7.82E-4 | 78782 |
[ |
HMI1 | Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of t... | 2 | 2 | 8.1% | 5.33E-4 | 80576 |
[ |
RSM22 | Mitochondrial ribosomal protein of the small subunit; also predicted to be an S-adenosylmethionine-d... | 3 | 3 | 8.1% | 8.99E-4 | 72190 |
[ |
ARA1 | NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer;... | 2 | 2 | 8.1% | 0.00109 | 38884 |
[ |
SPT2 | Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits... | 2 | 2 | 8.1% | 0.00113 | 38551 |
[ |
BEM3 | Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets... | 3 | 3 | 8.0% | 5.01E-4 | 124913 |
[ |
YJR061W | Putative protein of unknown function; non-essential gene with similarity to Mnn4, a putative membran... | 2 | 2 | 8.0% | 4.03E-4 | 108427 |
[ |
SDS23 | One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implic... | 2 | 2 | 8.0% | 7.14E-4 | 58112 |
[ |
DNM1 | Dynamin-related GTPase required for mitochondrial fission and morphology; assembles on the cytoplasm... | 2 | 2 | 7.9% | 4.97E-4 | 84972 |
[ |
AGE1 | ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory an... | 2 | 2 | 7.9% | 7.81E-4 | 54494 |
[ |
IMP4 | Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10... | 2 | 2 | 7.9% | 0.0013 | 33482 |
[ |
ADE3 | Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism ... | 3 | 3 | 7.8% | 5.97E-4 | 102205 |
[ |
STU2 | Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics duri... | 2 | 2 | 7.8% | 4.24E-4 | 100918 |
[ |
PMS1 | ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer ... | 3 | 3 | 7.8% | 6.47E-4 | 99355 |
[ |
NUP84 | Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13... | 3 | 3 | 7.7% | 7.78E-4 | 83635 |
[ |
ATM1 | Mitochondrial inner membrane ATP-binding cassette (ABC) transporter, exports mitochondrially synthes... | 2 | 2 | 7.7% | 5.46E-4 | 77522 |
[ |
BNA5 | Kynureninase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expressio... | 2 | 2 | 7.7% | 8.31E-4 | 51032 |
[ |
ATP3 | Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily ... | 2 | 2 | 7.7% | 0.00121 | 34351 |
[ |
ATG11 | Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; directs receptor... | 3 | 3 | 7.6% | 4.79E-4 | 135025 |
[ |
LCD1 | Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1... | 3 | 3 | 7.6% | 7.56E-4 | 86425 |
[ |
UTP5 | Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA a... | 2 | 2 | 7.6% | 5.85E-4 | 72002 |
[ |
YCK1 | Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p i... | 2 | 2 | 7.6% | 7.0E-4 | 61715 |
[ |
SWI4 | DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert ... | 4 | 4 | 7.5% | 6.89E-4 | 123806 |
[ |
YMR086W | Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ... | 3 | 3 | 7.5% | 5.88E-4 | 105874 |
[ |
HUL4 | Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability | 3 | 3 | 7.5% | 6.33E-4 | 103457 |
[ |
LEU9 | Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leuc... | 2 | 2 | 7.5% | 6.23E-4 | 67200 |
[ |
DEG1 | tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for m... | 2 | 2 | 7.5% | 8.52E-4 | 50889 |
[ |
TAF4 | TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p sub... | 2 | 2 | 7.5% | 9.7E-4 | 42336 |
[ |
BOI2 | Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence ... | 3 | 3 | 7.4% | 5.43E-4 | 115688 |
[ |
SWE1 | Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes... | 3 | 3 | 7.4% | 6.9E-4 | 92468 |
[ |
INP52 | Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI... | 2 | 2 | 7.3% | 3.18E-4 | 133331 |
[ |
FUN30 | Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Sn... | 4 | 4 | 7.3% | 6.66E-4 | 128507 |
[ |
HMG2 | One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in... | 4 | 4 | 7.3% | 7.21E-4 | 115692 |
[ |
BAS1 | Myb-related transcription factor involved in regulating basal and induced expression of genes of the... | 3 | 3 | 7.3% | 6.96E-4 | 89604 |
[ |
GIP2 | Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; conta... | 2 | 2 | 7.3% | 6.87E-4 | 62319 |
[ |
JHD1 | JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mous... | 2 | 2 | 7.3% | 7.65E-4 | 56530 |
[ |
MPH1 | Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that in... | 3 | 3 | 7.2% | 5.69E-4 | 114058 |
[ |
SRO77 | Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Gol... | 3 | 3 | 7.2% | 5.59E-4 | 111678 |
[ |
PUS1 | tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA... | 2 | 2 | 7.2% | 6.92E-4 | 62143 |
[ |
NUP1 | Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possibl... | 2 | 2 | 7.1% | 3.5E-4 | 113581 |
[ |
RSN1 | Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant cell... | 2 | 2 | 7.1% | 3.95E-4 | 107672 |
[ |
KAR3 | Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle... | 2 | 2 | 7.1% | 5.16E-4 | 84004 |
[ |
SKY1 | SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation home... | 2 | 2 | 7.1% | 5.07E-4 | 83238 |
[ |
STT3 | Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked ... | 2 | 2 | 7.1% | 5.24E-4 | 81529 |
[ |
ALY1 | Protein proposed to regulate the endocytosis of plasma membrane proteins by recruiting the ubiquitin... | 3 | 3 | 7.0% | 6.17E-4 | 102540 |
[ |
MKT1 | Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO endonu... | 3 | 3 | 7.0% | 6.8E-4 | 94494 |
[ |
MNN1 | Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for add... | 2 | 2 | 7.0% | 4.94E-4 | 88529 |
[ |
HDA3 | Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that ... | 2 | 2 | 7.0% | 5.75E-4 | 75463 |
[ |
ECM38 | Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of elec... | 2 | 2 | 7.0% | 5.7E-4 | 73181 |
[ |
STE5 | Pheromone-response scaffold protein; binds Ste11p, Ste7p, and Fus3p kinases, forming a MAPK cascade ... | 3 | 3 | 6.9% | 6.16E-4 | 102727 |
[ |
KIN4 | Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle positi... | 2 | 2 | 6.9% | 4.71E-4 | 90088 |
[ |
SMY2 | Protein of unknown function involved in COPII vesicle formation; interacts with the Sec23p/Sec24p su... | 2 | 2 | 6.9% | 5.09E-4 | 81397 |
[ |
ELM1 | Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokine... | 2 | 2 | 6.9% | 5.88E-4 | 72150 |
[ |
MPP10 | Component of the SSU processome and 90S preribosome, required for pre-18S rRNA processing, interacts... | 2 | 2 | 6.9% | 6.35E-4 | 66953 |
[ |
GUA1 | GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-ph... | 2 | 2 | 6.9% | 7.17E-4 | 58482 |
[ |
GCR2 | Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-bind... | 2 | 2 | 6.9% | 7.05E-4 | 58062 |
[ |
OCT1 | Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon impor... | 2 | 2 | 6.8% | 4.89E-4 | 87997 |
[ |
GLR1 | Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glu... | 2 | 2 | 6.8% | 7.79E-4 | 53441 |
[ |
COR1 | Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of ... | 2 | 2 | 6.8% | 8.24E-4 | 50228 |
[ |
SMC2 | Subunit of the condensin complex; essential SMC chromosomal ATPase family member that forms a comple... | 3 | 3 | 6.7% | 4.83E-4 | 133928 |
[ |
HSF1 | Trimeric heat shock transcription factor, activates multiple genes in response to stresses that incl... | 2 | 2 | 6.7% | 4.52E-4 | 93282 |
[ |
HSP78 | Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotoleranc... | 2 | 2 | 6.7% | 4.64E-4 | 91336 |
[ |
APL1 | Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle m... | 2 | 2 | 6.7% | 5.38E-4 | 80453 |
[ |
YOL075C | Putative ABC transporter | 3 | 3 | 6.6% | 4.36E-4 | 145157 |
[ |
RPN1 | Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the... | 2 | 2 | 6.6% | 3.79E-4 | 109492 |
[ |
SXM1 | Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucle... | 3 | 3 | 6.6% | 5.98E-4 | 108405 |
[ |
SYP1 | Protein of unknown function that is involved in endocytic site formation; may regulate assembly and ... | 2 | 2 | 6.6% | 4.33E-4 | 96137 |
[ |
YGL114W | Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family ... | 2 | 2 | 6.6% | 5.19E-4 | 80009 |
[ |
FRT1 | Tail-anchored, endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcine... | 2 | 2 | 6.6% | 6.25E-4 | 67293 |
[ |
UTP15 | Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is ... | 2 | 2 | 6.6% | 7.34E-4 | 57686 |
[ |
FAR11 | Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent... | 2 | 2 | 6.5% | 3.95E-4 | 109793 |
[ |
MYO2 | One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; requi... | 3 | 3 | 6.4% | 3.59E-4 | 180679 |
[ |
UFD4 | Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle ... | 3 | 3 | 6.4% | 3.81E-4 | 167842 |
[ |
POL3 | Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis a... | 2 | 2 | 6.4% | 3.43E-4 | 124591 |
[ |
ZDS1 | Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencin... | 2 | 2 | 6.4% | 4.11E-4 | 103358 |
[ |
YHR182W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 6.4% | 4.8E-4 | 90109 |
[ |
ADH3 | Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to ... | 2 | 2 | 6.4% | 0.001 | 40370 |
[ |
NPR3 | Component, with Npr2p, of an evolutionarily conserved complex that mediates downregulation of TOR Co... | 2 | 2 | 6.3% | 3.29E-4 | 129973 |
[ |
PMA1 | Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... | 2 | 2 | 6.3% | 4.1E-4 | 99619 |
[ |
PGM3 | Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcr... | 2 | 2 | 6.3% | 6.05E-4 | 71069 |
[ |
GCN2 | Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in re... | 4 | 4 | 6.2% | 4.54E-4 | 190193 |
[ |
DSE4 | Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the d... | 2 | 2 | 6.2% | 3.37E-4 | 121064 |
[ |
PSP2 | Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splic... | 2 | 2 | 6.2% | 6.35E-4 | 65584 |
[ |
PMA2 | Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator ... | 2 | 2 | 6.1% | 3.98E-4 | 102172 |
[ |
MSB1 | Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway... | 3 | 3 | 6.1% | 4.97E-4 | 129971 |
[ |
SEC5 | Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p,... | 2 | 2 | 6.1% | 3.88E-4 | 112121 |
[ |
SIN4 | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ... | 2 | 2 | 6.1% | 3.87E-4 | 111297 |
[ |
FOX2 | Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA d... | 2 | 2 | 6.1% | 4.18E-4 | 98703 |
[ |
DEF1 | RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and prot... | 2 | 2 | 6.1% | 5.1E-4 | 83973 |
[ |
FRE8 | Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion m... | 2 | 2 | 6.1% | 5.49E-4 | 78949 |
[ |
ORC2 | Subunit of the origin recognition complex, which directs DNA replication by binding to replication o... | 2 | 2 | 6.1% | 6.07E-4 | 71238 |
[ |
RFT1 | Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from th... | 2 | 2 | 6.1% | 6.56E-4 | 66211 |
[ |
YLR419W | Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged pr... | 3 | 3 | 6.0% | 3.94E-4 | 163044 |
[ |
RSC3 | Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper... | 2 | 2 | 6.0% | 4.25E-4 | 101720 |
[ |
MCM2 | Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin ... | 3 | 3 | 6.0% | 6.51E-4 | 98779 |
[ |
RPA135 | RNA polymerase I second largest subunit A135 | 2 | 2 | 5.9% | 3.13E-4 | 135742 |
[ |
NMD5 | Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog | 3 | 3 | 5.9% | 5.39E-4 | 119983 |
[ |
MGM1 | Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required f... | 2 | 2 | 5.9% | 4.17E-4 | 101523 |
[ |
GIS1 | JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes... | 2 | 2 | 5.9% | 4.21E-4 | 99481 |
[ |
APL4 | Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; invo... | 3 | 3 | 5.9% | 6.79E-4 | 93624 |
[ |
MEF1 | Mitochondrial elongation factor involved in translational elongation | 2 | 2 | 5.9% | 4.95E-4 | 84574 |
[ |
VBA2 | Permease of basic amino acids in the vacuolar membrane | 2 | 2 | 5.9% | 7.94E-4 | 51677 |
[ |
AIM22 | Putative lipoate-protein ligase, required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2... | 2 | 2 | 5.9% | 9.2E-4 | 47003 |
[ |
PIR1 | O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-gluc... | 2 | 2 | 5.9% | 0.0011 | 34622 |
[ |
SEN1 | Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs; h... | 5 | 5 | 5.8% | 4.22E-4 | 252495 |
[ |
DOP1 | Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, ... | 4 | 4 | 5.8% | 4.43E-4 | 194686 |
[ |
YOR1 | Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of man... | 3 | 3 | 5.8% | 3.82E-4 | 166727 |
[ |
SNT1 | Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; puta... | 2 | 2 | 5.8% | 3.07E-4 | 138397 |
[ |
POL5 | DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-t... | 2 | 2 | 5.8% | 3.68E-4 | 115894 |
[ |
POP1 | Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursor... | 2 | 2 | 5.8% | 4.3E-4 | 100395 |
[ |
VAC14 | Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some protei... | 2 | 2 | 5.8% | 4.28E-4 | 99773 |
[ |
PEX8 | Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal ... | 2 | 2 | 5.8% | 6.39E-4 | 68165 |
[ |
MEC1 | Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for... | 5 | 5 | 5.7% | 3.97E-4 | 273340 |
[ |
IRR1 | Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and m... | 2 | 2 | 5.7% | 3.27E-4 | 133009 |
[ |
MNR2 | Vacuolar membrane protein required for magnesium homeostasis; putative magnesium transporter; has si... | 2 | 2 | 5.7% | 3.89E-4 | 109736 |
[ |
RIX7 | Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucl... | 3 | 3 | 5.7% | 6.75E-4 | 93069 |
[ |
YER077C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 5.7% | 5.47E-4 | 79548 |
[ |
YLL058W | Putative protein of unknown function with similarity to Str2p, which is a cystathionine gamma-syntha... | 2 | 2 | 5.7% | 6.55E-4 | 64223 |
[ |
YHR097C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 5.7% | 0.00103 | 40663 |
[ |
BEM2 | Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cell... | 6 | 6 | 5.6% | 5.21E-4 | 245428 |
[ |
GDB1 | Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, ... | 3 | 3 | 5.5% | 3.68E-4 | 174971 |
[ |
BNR1 | Formin, nucleates the formation of linear actin filaments, involved in cell processes such as buddin... | 2 | 2 | 5.5% | 2.74E-4 | 156851 |
[ |
CAF120 | Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in control... | 2 | 2 | 5.5% | 3.55E-4 | 118280 |
[ |
HUL5 | Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins; works in op... | 2 | 2 | 5.5% | 4.14E-4 | 105566 |
[ |
SOV1 | Mitochondrial protein of unknown function | 2 | 2 | 5.5% | 4.19E-4 | 104748 |
[ |
PKH3 | Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh... | 2 | 2 | 5.5% | 4.19E-4 | 100476 |
[ |
PUF3 | Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anter... | 2 | 2 | 5.5% | 4.28E-4 | 98068 |
[ |
RRM3 | DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at... | 3 | 3 | 5.5% | 7.81E-4 | 81581 |
[ |
RPN4 | Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regula... | 2 | 2 | 5.5% | 7.09E-4 | 60153 |
[ |
RKR1 | Nuclear RING domain protein with functional connections to chromatin modification; may interact with... | 4 | 4 | 5.4% | 4.82E-4 | 180185 |
[ |
SWI1 | Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chr... | 2 | 2 | 5.4% | 2.87E-4 | 147937 |
[ |
COP1 | Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secr... | 2 | 2 | 5.4% | 3.13E-4 | 135607 |
[ |
NET1 | Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase e... | 3 | 3 | 5.4% | 4.75E-4 | 128531 |
[ |
RGA2 | GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of se... | 2 | 2 | 5.4% | 3.73E-4 | 113291 |
[ |
HSL7 | Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization ... | 2 | 2 | 5.4% | 4.55E-4 | 95153 |
[ |
ECM27 | Non-essential protein of unknown function | 2 | 2 | 5.4% | 5.19E-4 | 80657 |
[ |
DAS1 | Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and gene... | 2 | 2 | 5.4% | 5.68E-4 | 77367 |
[ |
BCK1 | Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathwa... | 3 | 3 | 5.3% | 3.82E-4 | 164195 |
[ |
MSH6 | Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair bo... | 2 | 2 | 5.3% | 3.03E-4 | 140080 |
[ |
ECM21 | Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrat... | 2 | 2 | 5.3% | 3.37E-4 | 123609 |
[ |
KAP114 | Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino termin... | 3 | 3 | 5.3% | 5.62E-4 | 113921 |
[ |
UPC2 | Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of... | 2 | 2 | 5.3% | 4.12E-4 | 100339 |
[ |
CUE3 | Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecu... | 2 | 2 | 5.3% | 6.03E-4 | 72043 |
[ |
VTH2 | Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in ... | 2 | 2 | 5.2% | 2.43E-4 | 174401 |
[ |
MDM1 | Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds;... | 2 | 2 | 5.2% | 3.34E-4 | 129981 |
[ |
CYM1 | Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin f... | 2 | 2 | 5.2% | 3.81E-4 | 112180 |
[ |
XRS2 | Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand ... | 2 | 2 | 5.2% | 4.41E-4 | 96364 |
[ |
IES1 | Subunit of the INO80 chromatin remodeling complex | 2 | 2 | 5.2% | 5.44E-4 | 78753 |
[ |
NCA2 | Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of th... | 3 | 3 | 5.2% | 9.17E-4 | 70862 |
[ |
HRP1 | Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation o... | 2 | 2 | 5.2% | 7.05E-4 | 59650 |
[ |
HSP150 | O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta... | 2 | 2 | 5.2% | 9.73E-4 | 38619 |
[ |
STE23 | Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature... | 2 | 2 | 5.1% | 3.67E-4 | 117579 |
[ |
SLA2 | Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization... | 2 | 2 | 5.1% | 3.89E-4 | 108996 |
[ |
SBE2 | Protein involved in the transport of cell wall components from the Golgi to the cell surface; requir... | 2 | 2 | 5.1% | 4.36E-4 | 98971 |
[ |
MES1 | Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which in... | 2 | 2 | 5.1% | 5.01E-4 | 85678 |
[ |
NOP4 | Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subun... | 2 | 2 | 5.1% | 5.5E-4 | 77825 |
[ |
ACS2 | Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histo... | 2 | 2 | 5.1% | 5.51E-4 | 75492 |
[ |
ALA1 | Cytoplasmic and mitochondrial alanyl-tRNA synthetase, required for protein synthesis; point mutation... | 2 | 2 | 5.0% | 3.93E-4 | 107277 |
[ |
CCZ1 | Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway | 2 | 2 | 5.0% | 5.35E-4 | 80732 |
[ |
MYO1 | Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the... | 3 | 3 | 4.9% | 2.93E-4 | 223634 |
[ |
HSL1 | Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates wit... | 3 | 3 | 4.9% | 3.72E-4 | 169592 |
[ |
SKI2 | Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic e... | 4 | 4 | 4.9% | 5.85E-4 | 146058 |
[ |
SLA1 | Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; inter... | 2 | 2 | 4.9% | 3.03E-4 | 135848 |
[ |
PCA1 | Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized ... | 2 | 2 | 4.9% | 3.1E-4 | 131839 |
[ |
CHS1 | Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-ac... | 2 | 2 | 4.9% | 3.33E-4 | 129919 |
[ |
HEF3 | Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates ... | 2 | 2 | 4.9% | 3.61E-4 | 115869 |
[ |
APE2 | Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; sequence coord... | 2 | 2 | 4.9% | 4.03E-4 | 105585 |
[ |
MOT2 | Subunit of the CCR4-NOT complex, which has roles in transcription regulation, mRNA degradation, and ... | 2 | 2 | 4.9% | 6.41E-4 | 65354 |
[ |
SAK1 | Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; mem... | 3 | 3 | 4.8% | 4.94E-4 | 126872 |
[ |
BUD2 | GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutan... | 2 | 2 | 4.8% | 3.41E-4 | 126663 |
[ |
PUF2 | Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that ... | 2 | 2 | 4.8% | 3.5E-4 | 119508 |
[ |
NUP116 | Subunit of the Nup82 subcomplex of the nuclear pore complex; localized to both sides of the pore; co... | 2 | 2 | 4.8% | 3.38E-4 | 116234 |
[ |
YTA12 | Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation ... | 2 | 2 | 4.8% | 4.56E-4 | 93276 |
[ |
EAF1 | Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 sub... | 2 | 2 | 4.7% | 3.83E-4 | 112502 |
[ |
CEX1 | Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nu... | 2 | 2 | 4.7% | 4.95E-4 | 84769 |
[ |
SPT21 | Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not... | 2 | 2 | 4.7% | 4.97E-4 | 84697 |
[ |
BDP1 | Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcri... | 2 | 2 | 4.7% | 6.34E-4 | 67688 |
[ |
MYO5 | One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletio... | 2 | 2 | 4.6% | 3.09E-4 | 136899 |
[ |
CHS3 | Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for ... | 2 | 2 | 4.6% | 3.23E-4 | 131601 |
[ |
ERB1 | Constituent of 66S pre-ribosomal particles, forms a complex with Nop7p and Ytm1p that is required fo... | 2 | 2 | 4.6% | 4.67E-4 | 91705 |
[ |
HO | Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) thr... | 2 | 2 | 4.6% | 6.42E-4 | 66089 |
[ |
DPL1 | Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base p... | 2 | 2 | 4.6% | 6.39E-4 | 65566 |
[ |
FKS1 | Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... | 3 | 3 | 4.5% | 3.01E-4 | 214849 |
[ |
VPS15 | Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a m... | 4 | 4 | 4.5% | 5.18E-4 | 166358 |
[ |
NUP157 | Abundant subunit of the nuclear pore complex (NPC), present on both sides of the NPC; has similarity... | 3 | 3 | 4.5% | 4.06E-4 | 156649 |
[ |
PMR1 | High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in C... | 2 | 2 | 4.5% | 3.96E-4 | 104571 |
[ |
SHE10 | Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression cau... | 2 | 2 | 4.5% | 6.52E-4 | 66862 |
[ |
RPA190 | RNA polymerase I largest subunit A190 | 2 | 2 | 4.4% | 2.26E-4 | 186431 |
[ |
BUD3 | Protein involved in bud-site selection and required for axial budding pattern; localizes with septin... | 3 | 3 | 4.4% | 3.45E-4 | 184718 |
[ |
BBC1 | Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las1... | 3 | 3 | 4.4% | 4.88E-4 | 128296 |
[ |
RAD26 | Protein involved in transcription-coupled nucleotide excision repair of UV-induced DNA lesions; recr... | 2 | 2 | 4.4% | 3.47E-4 | 124527 |
[ |
PFK2 | Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaero... | 3 | 3 | 4.4% | 5.89E-4 | 104618 |
[ |
STB6 | Protein that binds Sin3p in a two-hybrid assay | 2 | 2 | 4.4% | 4.91E-4 | 88836 |
[ |
SFL1 | Transcriptional repressor and activator; involved in repression of flocculation-related genes, and a... | 2 | 2 | 4.4% | 4.91E-4 | 83317 |
[ |
BZZ1 | SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polym... | 2 | 2 | 4.4% | 5.95E-4 | 71171 |
[ |
CDC20 | Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required fo... | 2 | 2 | 4.4% | 6.17E-4 | 67360 |
[ |
ATG21 | Phosphoinositide binding protein required for vesicle formation in the cytoplasm-to-vacuole targetin... | 2 | 2 | 4.4% | 7.59E-4 | 55188 |
[ |
YTP1 | Probable type-III integral membrane protein of unknown function, has regions of similarity to mitoch... | 2 | 2 | 4.4% | 8.2E-4 | 51644 |
[ |
GCN1 | Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate ... | 5 | 5 | 4.3% | 3.52E-4 | 296697 |
[ |
YGR109W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 4.3% | 2.43E-4 | 178419 |
[ |
ECM5 | Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibi... | 2 | 2 | 4.3% | 2.67E-4 | 162700 |
[ |
PAN1 | Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on th... | 3 | 3 | 4.3% | 3.82E-4 | 160266 |
[ |
TRZ1 | tRNA 3'-end processing endonuclease tRNase Z; also localized to mitochondria and interacts genetical... | 2 | 2 | 4.3% | 4.49E-4 | 96816 |
[ |
AI1 | Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intro... | 2 | 2 | 4.3% | 4.51E-4 | 96079 |
[ |
NOP14 | Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S rib... | 2 | 2 | 4.3% | 4.65E-4 | 94302 |
[ |
YFL054C | Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the prese... | 2 | 2 | 4.3% | 5.83E-4 | 70507 |
[ |
EXO5 | Mitochondrial 5'-3' exonuclease and sliding exonuclease, required for mitochondrial genome maintenan... | 2 | 2 | 4.3% | 6.44E-4 | 67570 |
[ |
GEA2 | Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transp... | 2 | 2 | 4.2% | 2.58E-4 | 165667 |
[ |
POL2 | Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhi... | 3 | 3 | 4.1% | 2.54E-4 | 255669 |
[ |
FAS1 | Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty a... | 2 | 2 | 4.1% | 1.84E-4 | 228689 |
[ |
RIM15 | Glucose-repressible protein kinase involved in signal transduction during cell proliferation in resp... | 3 | 3 | 4.1% | 3.19E-4 | 196530 |
[ |
CMR2 | Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-induc... | 2 | 2 | 4.1% | 2.28E-4 | 186906 |
[ |
SSK2 | MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, lead... | 4 | 4 | 4.1% | 4.77E-4 | 180527 |
[ |
INP51 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sa... | 2 | 2 | 4.1% | 3.98E-4 | 108430 |
[ |
GYP5 | GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; e... | 2 | 2 | 4.1% | 4.21E-4 | 101800 |
[ |
HBS1 | GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha... | 2 | 2 | 4.1% | 6.16E-4 | 68730 |
[ |
EXG2 | Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma me... | 2 | 2 | 4.1% | 6.7E-4 | 63508 |
[ |
DGA1 | Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acyl... | 2 | 2 | 4.1% | 9.01E-4 | 47711 |
[ |
SPT6 | Transcription elongation factor required for the maintenance of chromatin structure during transcrip... | 3 | 3 | 4.0% | 3.89E-4 | 168291 |
[ |
MDS3 | Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expr... | 3 | 3 | 4.0% | 3.8E-4 | 167074 |
[ |
MCM4 | Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexe... | 2 | 2 | 4.0% | 4.04E-4 | 105003 |
[ |
RAD54 | DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; i... | 2 | 2 | 4.0% | 4.19E-4 | 101754 |
[ |
HAL5 | Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disrupt... | 2 | 2 | 4.0% | 4.4E-4 | 95455 |
[ |
RAD53 | Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autopho... | 2 | 2 | 4.0% | 4.59E-4 | 91962 |
[ |
STT4 | Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for norma... | 3 | 3 | 3.9% | 2.97E-4 | 214605 |
[ |
AMS1 | Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vac... | 2 | 2 | 3.9% | 3.48E-4 | 124499 |
[ |
TSL1 | Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts ... | 2 | 2 | 3.9% | 3.43E-4 | 123018 |
[ |
ILS1 | Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A | 2 | 2 | 3.9% | 3.51E-4 | 122983 |
[ |
MTR4 | ATP-dependent 3'-5' RNA helicase, involved in nuclear RNA processing and degredation both as a compo... | 2 | 2 | 3.9% | 3.51E-4 | 122055 |
[ |
BUD27 | Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by TOR ki... | 2 | 2 | 3.9% | 4.73E-4 | 91422 |
[ |
RIF1 | Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telom... | 5 | 5 | 3.8% | 4.91E-4 | 217959 |
[ |
CDC25 | Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates ... | 2 | 2 | 3.8% | 2.37E-4 | 179091 |
[ |
SNT2 | DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a ... | 3 | 3 | 3.8% | 4.02E-4 | 163203 |
[ |
YOR296W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 3 | 3 | 3.8% | 4.38E-4 | 147426 |
[ |
NST1 | Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the spli... | 2 | 2 | 3.8% | 3.04E-4 | 141514 |
[ |
NEW1 | ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the s... | 2 | 2 | 3.8% | 3.15E-4 | 134331 |
[ |
ZRG8 | Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondr... | 2 | 2 | 3.8% | 3.5E-4 | 119350 |
[ |
WAR1 | Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induc... | 2 | 2 | 3.8% | 3.99E-4 | 107560 |
[ |
NOT3 | Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcrip... | 2 | 2 | 3.8% | 4.5E-4 | 94403 |
[ |
VID27 | Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not esse... | 2 | 2 | 3.8% | 4.81E-4 | 88846 |
[ |
RGD1 | GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytosk... | 2 | 2 | 3.8% | 5.65E-4 | 74619 |
[ |
SIT1 | Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize sid... | 2 | 2 | 3.8% | 5.99E-4 | 70562 |
[ |
HBT1 | Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); m... | 2 | 2 | 3.7% | 3.6E-4 | 113616 |
[ |
VID22 | Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,... | 2 | 2 | 3.7% | 4.18E-4 | 102499 |
[ |
YSH1 | Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex; req... | 3 | 3 | 3.7% | 7.25E-4 | 87674 |
[ |
TOR2 | PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth i... | 3 | 3 | 3.6% | 2.28E-4 | 281566 |
[ |
RPO21 | RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapep... | 3 | 3 | 3.6% | 3.26E-4 | 191610 |
[ |
SIN3 | Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and... | 2 | 2 | 3.6% | 2.45E-4 | 174838 |
[ |
ARO1 | Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which i... | 2 | 2 | 3.6% | 2.37E-4 | 174754 |
[ |
RAV1 | Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym... | 2 | 2 | 3.6% | 2.77E-4 | 154932 |
[ |
NUP145 | Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that ass... | 2 | 2 | 3.6% | 2.86E-4 | 145661 |
[ |
RRP12 | Protein required for export of the ribosomal subunits; associates with the RNA components of the pre... | 2 | 2 | 3.6% | 3.07E-4 | 137508 |
[ |
YMR196W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 2 | 3.6% | 3.46E-4 | 126624 |
[ |
STE20 | Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family; involved in phe... | 2 | 2 | 3.6% | 4.01E-4 | 102362 |
[ |
APC1 | Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein li... | 3 | 3 | 3.5% | 3.23E-4 | 196143 |
[ |
IRC20 | Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene;... | 2 | 2 | 3.5% | 2.42E-4 | 180343 |
[ |
PDR15 | Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress res... | 2 | 2 | 3.5% | 2.46E-4 | 172255 |
[ |
SSN2 | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ... | 2 | 2 | 3.5% | 2.65E-4 | 160000 |
[ |
ADE6 | Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucle... | 2 | 2 | 3.5% | 2.77E-4 | 148904 |
[ |
FUN12 | GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes a... | 2 | 2 | 3.5% | 3.76E-4 | 112268 |
[ |
SPC98 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 2 | 2 | 3.5% | 4.45E-4 | 98227 |
[ |
SPC97 | Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the... | 2 | 2 | 3.5% | 4.57E-4 | 96825 |
[ |
VPH1 | Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V... | 2 | 2 | 3.5% | 4.48E-4 | 95529 |
[ |
MBP1 | Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a co... | 2 | 2 | 3.5% | 4.52E-4 | 93908 |
[ |
YLL054C | Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional ac... | 2 | 2 | 3.5% | 4.9E-4 | 89163 |
[ |
UTP4 | Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in pr... | 2 | 2 | 3.5% | 4.85E-4 | 87801 |
[ |
DCR2 | Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via de... | 2 | 2 | 3.5% | 6.51E-4 | 66463 |
[ |
SCC2 | Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes... | 2 | 2 | 3.4% | 2.52E-4 | 171101 |
[ |
PEP5 | Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein tra... | 2 | 2 | 3.4% | 3.66E-4 | 117477 |
[ |
COG4 | Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tet... | 2 | 2 | 3.4% | 4.37E-4 | 98665 |
[ |
RAD4 | Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subun... | 2 | 2 | 3.4% | 4.99E-4 | 87204 |
[ |
FMP27 | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... | 4 | 4 | 3.3% | 2.87E-4 | 303478 |
[ |
SEC3 | Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which me... | 3 | 3 | 3.3% | 4.23E-4 | 154694 |
[ |
BMS1 | GTPase required for synthesis of 40S ribosomal subunits and for processing the 35S pre-rRNA at sites... | 2 | 2 | 3.3% | 3.18E-4 | 135571 |
[ |
MET18 | DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymeras... | 2 | 2 | 3.3% | 3.65E-4 | 117882 |
[ |
VPS13 | Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated wit... | 3 | 3 | 3.2% | 1.8E-4 | 357850 |
[ |
PMD1 | Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expr... | 3 | 3 | 3.2% | 3.22E-4 | 195382 |
[ |
ULS1 | RING finger protein involved in proteolytic control of sumoylated substrates; interacts with SUMO (S... | 3 | 3 | 3.2% | 3.49E-4 | 184404 |
[ |
YDL073W | Putative protein of unknown function; YDL073W is not an essential gene | 2 | 2 | 3.2% | 3.83E-4 | 113891 |
[ |
YNL313C | Essential protein of unknown function; fluorescent protein (GFP or YFP)-tagged protein localizes to ... | 2 | 2 | 3.2% | 4.16E-4 | 102336 |
[ |
APL6 | Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the ... | 2 | 2 | 3.2% | 4.65E-4 | 91607 |
[ |
ACC1 | Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to f... | 2 | 2 | 3.1% | 1.69E-4 | 250351 |
[ |
SEC7 | Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of t... | 2 | 2 | 3.1% | 1.87E-4 | 226884 |
[ |
MYO3 | One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect o... | 2 | 2 | 3.1% | 2.96E-4 | 142507 |
[ |
RIA1 | Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongat... | 2 | 2 | 3.1% | 3.39E-4 | 124464 |
[ |
UBP7 | Ubiquitin-specific protease that cleaves ubiquitin-protein fusions | 2 | 2 | 3.1% | 3.52E-4 | 123134 |
[ |
YPL150W | Putative protein kinase of unknown cellular role | 2 | 2 | 3.1% | 4.18E-4 | 100646 |
[ |
TRP3 | Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase a... | 2 | 2 | 3.1% | 7.78E-4 | 53489 |
[ |
GSC2 | Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore... | 3 | 3 | 3.0% | 2.98E-4 | 216988 |
[ |
YIL177C | Putative protein of unknown function; similarity to DNA helicases that are encoded within subtelomer... | 4 | 4 | 3.0% | 4.28E-4 | 197511 |
[ |
YJL225C | Putative protein of unknown function; similarity to DNA helicases that are also encoded within subte... | 4 | 4 | 3.0% | 4.28E-4 | 197564 |
[ |
STU1 | Component of the mitotic spindle that binds to interpolar microtubules via its association with beta... | 4 | 4 | 3.0% | 4.98E-4 | 174176 |
[ |
TOF1 | Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled rep... | 2 | 2 | 3.0% | 3.04E-4 | 141120 |
[ |
GIN4 | Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-depen... | 2 | 2 | 3.0% | 3.3E-4 | 129858 |
[ |
HOS4 | Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes tha... | 2 | 2 | 3.0% | 3.48E-4 | 123556 |
[ |
KRE33 | Essential protein, required for biogenesis of the small ribosomal subunit; heterozygous mutant shows... | 2 | 2 | 3.0% | 3.57E-4 | 119347 |
[ |
UTP14 | Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA a... | 2 | 2 | 3.0% | 4.19E-4 | 103023 |
[ |
MYO4 | One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; requi... | 2 | 2 | 2.9% | 2.56E-4 | 169343 |
[ |
NAT1 | Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many... | 2 | 2 | 2.9% | 4.41E-4 | 98905 |
[ |
PUT3 | Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter ... | 2 | 2 | 2.8% | 3.85E-4 | 111414 |
[ |
MOT1 | Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA vi... | 2 | 2 | 2.7% | 2.02E-4 | 209975 |
[ |
NFT1 | Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs Y... | 2 | 2 | 2.7% | 3.09E-4 | 137996 |
[ |
BUL1 | Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, d... | 2 | 4 | 2.7% | 7.71E-4 | 109174 |
[ |
VPS52 | Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, wh... | 2 | 2 | 2.7% | 5.87E-4 | 74333 |
[ |
BNI1 | Formin, nucleates the formation of linear actin filaments, involved in cell processes such as buddin... | 2 | 2 | 2.6% | 1.93E-4 | 219701 |
[ |
YHL009W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.6% | 2.09E-4 | 207969 |
[ |
CHD1 | Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a ch... | 2 | 2 | 2.6% | 2.56E-4 | 168240 |
[ |
TAF2 | TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation | 2 | 2 | 2.6% | 2.68E-4 | 161470 |
[ |
SPO71 | Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; ... | 2 | 2 | 2.6% | 3.02E-4 | 145181 |
[ |
PRP8 | Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutation... | 2 | 2 | 2.5% | 1.56E-4 | 279502 |
[ |
LAA1 | AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endos... | 2 | 2 | 2.5% | 1.87E-4 | 229898 |
[ |
CYR1 | Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAM... | 3 | 3 | 2.5% | 2.79E-4 | 227832 |
[ |
YER138C | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.5% | 2.15E-4 | 198561 |
[ |
YDR316W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.5% | 2.15E-4 | 198526 |
[ |
YDR098C-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.5% | 2.15E-4 | 198594 |
[ |
YGR038C-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.5% | 2.15E-4 | 198520 |
[ |
YER160C | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 2 | 2 | 2.5% | 2.15E-4 | 198568 |
[ |
KRE5 | Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and sever... | 3 | 3 | 2.5% | 4.14E-4 | 156477 |
[ |
PDS5 | Protein required for establishment and maintenance of sister chromatid condensation and cohesion, co... | 2 | 2 | 2.5% | 2.95E-4 | 147041 |
[ |
PDR12 | Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter re... | 2 | 2 | 2.4% | 2.49E-4 | 171064 |
[ |
SKI3 | Ski complex component and TPR protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; nu... | 2 | 2 | 2.4% | 2.63E-4 | 163725 |
[ |
PSK1 | One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein... | 2 | 2 | 2.4% | 2.78E-4 | 152330 |
[ |
UBP15 | Ubiquitin-specific protease that may play a role in ubiquitin precursor processing | 2 | 2 | 2.4% | 3.06E-4 | 143563 |
[ |
OXP1 | 5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green... | 2 | 2 | 2.4% | 2.93E-4 | 140427 |
[ |
VPS35 | Endosomal subunit of membrane-associated retromer complex required for retrograde transport; recepto... | 2 | 2 | 2.4% | 3.99E-4 | 109142 |
[ |
ADY3 | Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structu... | 2 | 2 | 2.4% | 4.77E-4 | 91740 |
[ |
SPO14 | Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic... | 2 | 2 | 2.3% | 2.24E-4 | 195203 |
[ |
BUD4 | Protein involved in bud-site selection and required for axial budding pattern; localizes with septin... | 2 | 2 | 2.3% | 2.6E-4 | 165023 |
[ |
NUP133 | Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the N... | 2 | 2 | 2.3% | 3.25E-4 | 133320 |
[ |
RAT1 | Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snR... | 2 | 2 | 2.3% | 3.74E-4 | 115934 |
[ |
ROD1 | Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers r... | 2 | 2 | 2.3% | 4.5E-4 | 92349 |
[ |
URA2 | Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes t... | 2 | 2 | 2.2% | 1.7E-4 | 245123 |
[ |
PRP22 | DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates befor... | 2 | 2 | 2.2% | 3.29E-4 | 130010 |
[ |
YKL105C | Putative protein of unknown function | 2 | 2 | 2.2% | 3.33E-4 | 125593 |
[ |
ENA5 | Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family | 2 | 2 | 2.2% | 3.45E-4 | 120296 |
[ |
ENA1 | P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance | 2 | 2 | 2.2% | 3.45E-4 | 120357 |
[ |
ENA2 | P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li... | 2 | 2 | 2.2% | 3.45E-4 | 120317 |
[ |
SLH1 | Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; req... | 2 | 2 | 2.1% | 1.91E-4 | 224828 |
[ |
NUP188 | Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex an... | 2 | 2 | 2.1% | 2.27E-4 | 188576 |
[ |
IML1 | Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuola... | 2 | 2 | 2.0% | 2.38E-4 | 181948 |
[ |
RAD50 | Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in ve... | 2 | 2 | 2.0% | 2.87E-4 | 152568 |
[ |
SMC1 | Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation an... | 2 | 2 | 2.0% | 3.07E-4 | 141280 |
[ |
YLR422W | Protein of unknown function with similarity to human DOCK proteins (guanine nucleotide exchange fact... | 2 | 2 | 1.9% | 1.95E-4 | 221562 |
[ |
YBL100W-B | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 3 | 3 | 1.9% | 3.19E-4 | 202214 |
[ |
STH1 | ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic g... | 2 | 2 | 1.9% | 2.77E-4 | 156742 |
[ |
TEL1 | Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoin... | 2 | 2 | 1.8% | 1.35E-4 | 321568 |
[ |
TOR1 | PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in... | 3 | 3 | 1.8% | 2.29E-4 | 281138 |
[ |
FAB1 | 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylino... | 3 | 3 | 1.8% | 2.48E-4 | 257447 |
[ |
DNF3 | Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secre... | 2 | 2 | 1.8% | 2.27E-4 | 188318 |
[ |
TRK1 | Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter... | 2 | 2 | 1.8% | 3.05E-4 | 141073 |
[ |
CSF1 | Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected ... | 3 | 4 | 1.7% | 2.55E-4 | 338258 |
[ |
UTP20 | Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA | 2 | 2 | 1.7% | 1.51E-4 | 287559 |
[ |
ECM16 | Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in ... | 2 | 2 | 1.7% | 2.97E-4 | 144954 |
[ |
CHC1 | Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport ... | 2 | 2 | 1.6% | 2.28E-4 | 187233 |
[ |
SSM4 | Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear en... | 2 | 2 | 1.6% | 2.85E-4 | 151454 |
[ |
NUM1 | Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may med... | 2 | 2 | 1.5% | 1.37E-4 | 313032 |
[ |
GLT1 | NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglut... | 2 | 2 | 1.5% | 1.76E-4 | 238100 |
[ |
PMC1 | Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activ... | 2 | 2 | 1.5% | 3.21E-4 | 130861 |
[ |
BRR2 | RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in nativ... | 2 | 2 | 1.4% | 1.74E-4 | 246183 |
[ |
YPR117W | Putative protein of unknown function | 2 | 2 | 1.3% | 1.51E-4 | 285902 |
[ |
TAO3 | Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular... | 2 | 2 | 1.3% | 1.58E-4 | 269856 |
[ |
DYN1 | Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation;... | 2 | 2 | 0.8% | 9.2E-5 | 471351 |
[ |
TOM1 | E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may reg... | 2 | 2 | 0.6% | 1.15E-4 | 374186 |