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The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. Complex formation involves dimerization of a receptor protein tyrosine kinase followed by the association of several different intracellular signaling molecules with the cytoplasmic tails of the receptors. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). The process whose specific outcome is the progression of the neuromuscular junction over time, from its formation to the mature structure. Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. The maintenance of membrane composition in a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The accumulation of acetylcholine receptors (AChRs) in a narrow, central region of muscle fibers, in apposition to nerve terminals.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: skeletal muscle nicotinic acetylcholine receptor clustering
Acc: GO:0071340
Aspect: Biological Process
Desc: The accumulation of acetylcholine receptors (AChRs) in a narrow, central region of muscle fibers, in apposition to nerve terminals.
Synonyms:
  • skeletal muscle AChR clustering
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0071340 - skeletal muscle nicotinic acetylcholine receptor clustering (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle