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Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell. A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The process by which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tRNA gene clustering
Acc: GO:0070058
Aspect: Biological Process
Desc: The process by which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070058 - tRNA gene clustering (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle