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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
Acc: GO:0070032
Aspect: Cellular Component
Desc: A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).
Synonyms:
  • Vamp2-Snap25-Stx1a-Cplx1 complex
  • SNARE complex (Vamp2, Snap25, Stx1a, Cplx1)
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070032 - synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex (interactive image map)

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Created and Maintained by: Michael Riffle