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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that decreases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that stops, prevents or reduces the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B, which occurs as a result of a single trigger reaction or compound. Any process that modulates the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of protein kinase B signaling cascade
Acc: GO:0051898
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
Synonyms:
  • down regulation of protein kinase B signaling cascade
  • negative regulation of PKB signaling cascade
  • downregulation of protein kinase B signaling cascade
  • negative regulation of PKB signalling cascade
  • negative regulation of protein kinase B signalling cascade
  • inhibition of protein kinase B signaling cascade
  • negative regulation of AKT signalling cascade
  • negative regulation of AKT signaling cascade
  • down-regulation of protein kinase B signaling cascade
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 23 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051898 - negative regulation of protein kinase B signaling cascade (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle