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The cell cycle process whereby paired chromosomes are detached from each other. In budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process by which sister chromatids are physically detached from each other during mitosis. A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. The process by which sister chromatids are physically detached from each other during mitosis. The process by which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mitotic sister chromatid separation
Acc: GO:0051306
Aspect: Biological Process
Desc: The process by which sister chromatids are physically detached from each other during mitosis.
Synonyms:
  • sister chromatid separation during mitosis
  • mitotic chromosome separation
  • chromosome separation during mitosis
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051306 - mitotic sister chromatid separation (interactive image map)
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