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The regrowth of axons following their loss or damage. The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage. Any process that modulates the frequency, rate or extent of a response to an external stimulus. Any process that stops, prevents or reduces the frequency, rate or extent of a response to an external stimulus. Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Any process that stops, prevents or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus. Any process that stops, prevents or reduces the frequency, rate or extent of sprouting of an injured axon. Any process that modulates the frequency, rate or extent of axon regeneration. Any process that stops, prevents or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. Any process that stops, prevents or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons. Any process that stops, prevents or reduces the frequency, rate or extent of axon regeneration. Any process that stops, prevents or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). Any process that stops, prevents or reduces the frequency, rate or extent of axonogenesis. Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of axon regeneration
Acc: GO:0048681
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of axon regeneration.
Synonyms:
  • down-regulation of axon regeneration
  • down regulation of axon regeneration
  • inhibition of axon regeneration
  • downregulation of axon regeneration
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048681 - negative regulation of axon regeneration (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle