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The binding of a cell to the extracellular matrix via adhesion molecules. A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. The attachment of a cell to the underlying substrate via adhesion molecules. The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions. Any process that stops, prevents or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: focal adhesion assembly
Acc: GO:0048041
Aspect: Biological Process
Desc: The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
Synonyms:
  • focal adhesion formation
Proteins in PDR annotated with:
   This term: 24 [Search]
   Term or descendants: 47 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048041 - focal adhesion assembly (interactive image map)

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