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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that modulates the frequency, rate or extent of a signaling pathway. Any process that modulates the frequency, rate or extent of the sevenless signaling pathway. The series of molecular signals generated as a consequence of the sevenless receptor binding to one of its physiological ligands. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Any process that modulates the frequency, rate or extent of R7 differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of the sevenless signaling pathway. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. The process whereby the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of sevenless signaling pathway
Acc: GO:0045873
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the sevenless signaling pathway.
Synonyms:
  • negative regulation of sev signaling pathway
  • inhibition of sevenless signaling pathway
  • down regulation of sevenless signaling pathway
  • downregulation of sevenless signaling pathway
  • negative regulation of sevenless signalling pathway
  • down-regulation of sevenless signaling pathway
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045873 - negative regulation of sevenless signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle