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The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. Any process that stops, prevents or reduces the frequency, rate or extent of global transcription from an RNA polymerase II promoter. Any process that modulates the frequency, rate or extent of global transcription from Pol II promoter. Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of transcription from RNA polymerase II promoter, global
Acc: GO:0045816
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of global transcription from an RNA polymerase II promoter.
Synonyms:
  • downregulation of global transcription from RNA polymerase II promoter
  • inhibition of global transcription from RNA polymerase II promoter
  • down regulation of global transcription from RNA polymerase II promoter
  • down-regulation of global transcription from RNA polymerase II promoter
  • negative regulation of global transcription from Pol II promoter
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045816 - negative regulation of transcription from RNA polymerase II promoter, global (interactive image map)
YRC Informatics Platform - Version 3.0
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