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The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. Any process that activates or increases the frequency, rate, or extent of mast cell activation. Any process that stops, prevents or reduces the frequency, rate, or extent of mast cell activation. Any process that modulates the frequency, rate, or extent of mast cell activation. A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mast cell activation
Acc: GO:0045576
Aspect: Biological Process
Desc: The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 57 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045576 - mast cell activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle