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Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound. Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor. Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: glutathione dehydrogenase (ascorbate) activity
Acc: GO:0045174
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
Synonyms:
  • dehydroascorbic acid reductase activity
  • GDOR
  • dehydroascorbic reductase activity
  • glutathione dehydroascorbate reductase activity
  • glutathione:dehydroascorbate oxidoreductase activity
  • dehydroascorbate reductase activity
  • DHA reductase activity
  • glutathione:dehydroascorbic acid oxidoreductase activity
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045174 - glutathione dehydrogenase (ascorbate) activity (interactive image map)

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