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Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. The aggregation, arrangement and bonding together of a cellular component. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. The process by which a cellular component is synthesized, aggregates, and bonds together. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. The formation of the bundles of intermediate filaments, known as tonofilaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: intermediate filament bundle assembly
Acc: GO:0045110
Aspect: Biological Process
Desc: The formation of the bundles of intermediate filaments, known as tonofilaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.
Synonyms:
  • tonofilament assembly
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045110 - intermediate filament bundle assembly (interactive image map)

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