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The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. The process by which a cell in a multicellular organism interprets its surroundings. The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. The process by which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis. The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: recognition of apoptotic cell
Acc: GO:0043654
Aspect: Biological Process
Desc: The process by which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.
Synonyms:
  • recognition of cell corpse
  • recognition of apoptotic cell corpse
  • detection of apoptotic cell
  • detection of apoptotic cell corpse
  • detection of cell corpse
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043654 - recognition of apoptotic cell (interactive image map)

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