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The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin moiety, or multiple ubiquitin moieties, to the protein. The process of directing proteins towards a membrane, usually using signals contained within the protein. The process of directing proteins towards a membrane using signals contained within the protein, occurring during ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway
Acc: GO:0043329
Aspect: Biological Process
Desc: The process of directing proteins towards a membrane using signals contained within the protein, occurring during ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway.
Synonyms:
  • protein membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway
  • protein-membrane targeting during ubiquitin-dependent protein degradation via the MVB pathway
  • protein targeting to membrane during ubiquitin-dependent protein degradation via the MVB pathway
  • protein membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway
  • protein-membrane targeting during ubiquitin-dependent protein breakdown via the MVB pathway
  • protein-membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway
  • protein targeting to membrane during ubiquitin-dependent protein breakdown via the MVB pathway
  • protein-membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043329 - protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle