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A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. A plasma membrane part that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. A cell junction that forms a connection between two cells; excludes direct cytoplasmic junctions such as ring canals. The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells. The apical end of the lateral plasma membrane of epithelial cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: subapical complex
Acc: GO:0035003
Aspect: Cellular Component
Desc: The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
Synonyms:
  • SAC
Proteins in PDR annotated with:
   This term: 31 [Search]
   Term or descendants: 31 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035003 - subapical complex (interactive image map)
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